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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 106978162.

Expression and function of Caenorhabditis elegans UNCP-18, a paralog of the SM protein UNC-18

Marion Boeglin, Eduardo Leyva-Díaz, Oliver Hobert

Genetics. 2023 Dec; 225(4): iyad180. Published online 2023 Oct 5. doi: 10.1093/genetics/iyad180

PMCID:: PMC10697816

Abstract Article PDF–6.1M

Select item 103356763.

Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

Zhongliang Hu, Yamei Luo, Yuting Liu, Yaru Luo, Liangce Wang, Shengsong Gou, Yuling Peng, Rui Wei, Da Jia, Yuan Wang, Shangbang Gao, Yan Zhang

PLoS Biol. 2023 Jul; 21(7): e3002165. Published online 2023 Jul 11. doi: 10.1371/journal.pbio.3002165

PMCID:: PMC10335676

Abstract Article PDF–2.2M

Select item 101015004.

The active zone protein Clarinet regulates synaptic sorting of ATG-9 and presynaptic autophagy

Zhao Xuan, Sisi Yang, Benjamin Clark, Sarah E. Hill, Laura Manning, Daniel A. Colón-Ramos

PLoS Biol. 2023 Apr; 21(4): e3002030. Published online 2023 Apr 13. doi: 10.1371/journal.pbio.3002030

PMCID:: PMC10101500

Abstract Article PDF–4.4M

Select item 97709885.

GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans

Jieyu Wu, Liuyang Wang, John F. Ervin, Shih-Hsiu J. Wang, Erik Soderblom, Dennis Ko, Dong Yan

Sci Adv. 2022 Dec; 8(51): eadc9236. Published online 2022 Dec 21. doi: 10.1126/sciadv.adc9236

PMCID:: PMC9770988

Abstract Article PDF–2.2M

Select item 95309236.

The use of CRISPR to generate a whole-gene humanized MAPT and the examination of P301L and G272V clinical variants, along with the creation of deletion null alleles of ptl-1, pgrn-1 and alfa-1 loci

Jeremy Lins, Christopher E. Hopkins, Trisha Brock, Anne C. Hart

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000615. Published online 2022 Sep 19. doi: 10.17912/micropub.biology.000615

PMCID:: PMC9530923

Abstract Article PDF–443K

Select item 94378487.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 92137048.

Interspecies complementation identifies a pathway to assemble SNAREs

Leonardo A. Parra-Rivas, Mark T. Palfreyman, Thien N. Vu, Erik M. Jorgensen

iScience. 2022 Jul 15; 25(7): 104506. Published online 2022 Jun 2. doi: 10.1016/j.isci.2022.104506

PMCID:: PMC9213704

Abstract Article PDF–12M

Select item 90170689.

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

Sisi Yang, Daehun Park, Laura Manning, Sarah E. Hill, Mian Cao, Zhao Xuan, Ian Gonzalez, Yongming Dong, Benjamin Clark, Lin Shao, Ifechukwu Okeke, Agustin Almoril-Porras, Jihong Bai, Pietro De Camilli, Daniel A. Colón-Ramos

Neuron. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: Neuron. 2022 Mar 2; 110(5): 824–840.e10. Published online 2022 Jan 21. doi: 10.1016/j.neuron.2021.12.031

PMCID:: PMC9017068

Abstract Article PDF–3.3M

Select item 861412110.

Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized Caenorhabditis elegans

Bangfu Zhu, Jennifer C. H. Mak, Andrew P. Morris, Anthony G. Marson, Jeff W. Barclay, Graeme J. Sills, Alan Morgan

Epilepsia. 2020 Apr; 61(4): 810–821. Published online 2020 Feb 29. doi: 10.1111/epi.16464

PMCID:: PMC8614121

Abstract Article PDF–1.1M

Select item 852750611.

Conditional immobilization for live imaging Caenorhabditis elegans using auxin-dependent protein depletion

Cori K Cahoon, Diana E Libuda

G3 (Bethesda) 2021 Nov; 11(11): jkab310. Published online 2021 Sep 2. doi: 10.1093/g3journal/jkab310

PMCID:: PMC8527506

Abstract Article PDF–2.0M

Select item 844679312.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 833118313.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517614.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4