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Items: 13

Select item 96915421.

Co-opted genes of algal origin protect C. elegans against cyanogenic toxins

Bingying Wang, Taruna Pandey, Yong Long, Sofia E. Delgado-Rodriguez, Matthew D. Daugherty, Dengke K. Ma

Curr Biol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: Curr Biol. 2022 Nov 21; 32(22): 4941–4948.e3. Published online 2022 Oct 11. doi: 10.1016/j.cub.2022.09.041

PMCID:: PMC9691542

Abstract Article PDF–1.9M

Select item 95791512.

The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans

Mehul Vora, Stephanie M. Pyonteck, Tatiana Popovitchenko, Tarmie L. Matlack, Aparna Prashar, Nanci S. Kane, John Favate, Premal Shah, Christopher Rongo

Nat Commun. 2022; 13: 6168. Published online 2022 Oct 18. doi: 10.1038/s41467-022-33849-x

PMCID:: PMC9579151

Abstract Article PDF–2.9M

Select item 95481813.

Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents

Alan D. Winter, Elissa Tjahjono, Leonardo J. Beltrán, Iain L. Johnstone, Neil J. Bulleid, Antony P. Page

BMC Biol. 2022; 20: 228. Published online 2022 Oct 8. doi: 10.1186/s12915-022-01415-y

PMCID:: PMC9548181

Abstract Article PDF–2.5M

Select item 87531224.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 77329225.

Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response

Joseph C.P. Kruempel, Hillary A. Miller, Megan L. Schaller, Abrielle Fretz, Marshall Howington, Marjana Sarker, Shijiao Huang, Scott F. Leiser

GeroScience. 2020 Dec; 42(6): 1621–1633. Published online 2020 May 12. doi: 10.1007/s11357-020-00194-0

PMCID:: PMC7732922

Abstract Article PDF–1.2M

Select item 71420826.

Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection

Nicholas O. Burton, Cristian Riccio, Alexandra Dallaire, Jonathan Price, Benjamin Jenkins, Albert Koulman, Eric A. Miska

Nat Commun. 2020; 11: 1741. Published online 2020 Apr 8. doi: 10.1038/s41467-020-15555-8

PMCID:: PMC7142082

Abstract Article PDF–1.0M

Select item 67819077.

A Novel Mechanism To Prevent H₂S Toxicity in Caenorhabditis elegans

Joseph W. Horsman, Frazer I. Heinis, Dana L. Miller

Genetics. 2019 Oct; 213(2): 481–490. Published online 2019 Aug 1. doi: 10.1534/genetics.119.302326

PMCID:: PMC6781907

Abstract Article PDF–1.2M

Select item 56760698.

Genetic interaction with temperature is an important determinant of nematode longevity

Hillary Miller, Marissa Fletcher, Melissa Primitivo, Alison Leonard, George L. Sutphin, Nicholas Rintala, Matt Kaeberlein, Scott F. Leiser

Aging Cell. 2017 Dec; 16(6): 1425–1429. Published online 2017 Sep 21. doi: 10.1111/acel.12658

PMCID:: PMC5676069

Abstract Article PDF–884K

Select item 33211729.

Hypoxia regulates glutamate receptor trafficking through an HIF-independent mechanism

Eun Chan Park, Piya Ghose, Zhiyong Shao, Qi Ye, Lijun Kang, X Z Shawn Xu, Jo Anne Powell-Coffman, Christopher Rongo

EMBO J. 2012 Mar 21; 31(6): 1379–1393. Published online 2012 Jan 17. doi: 10.1038/emboj.2011.499

Correction in:: EMBO J. 2012 Mar 21; 31(6): 1618–1619.

PMCID:: PMC3321172

Abstract Article PDF–2.5M

Select item 330581310.

CYSL-1 Interacts with the O₂-sensing Hydroxylase EGL-9 to Promote H₂S-modulated Hypoxia-induced Behavioral Plasticity in C. elegans

Dengke K. Ma, Roman Vozdek, Nikhil Bhatla, H. Robert Horvitz

Neuron. Author manuscript; available in PMC 2013 Mar 8.

Published in final edited form as: Neuron. 2012 Mar 8; 73(5): 925–940. doi: 10.1016/j.neuron.2011.12.037

PMCID:: PMC3305813

Abstract Article PDF–5.2M

Select item 292881611.

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1

Zhiyong Shao, Yi Zhang, Qi Ye, Jenifer Neeta Saldanha, Jo Anne Powell-Coffman

PLoS Pathog. 2010 Aug; 6(8): e1001075. Published online 2010 Aug 26. doi: 10.1371/journal.ppat.1001075

PMCID:: PMC2928816

Abstract Article PDF–1.1M

Select item 278547712.

Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans

Audrey Bellier, Chang-Shi Chen, Cheng-Yuan Kao, Hediye N. Cinar, Raffi V. Aroian

PLoS Pathog. 2009 Dec; 5(12): e1000689. Published online 2009 Dec 11. doi: 10.1371/journal.ppat.1000689

PMCID:: PMC2785477

Abstract Article PDF–1.2M

Select item 166707513.

The Caenorhabditis elegans rhy-1 Gene Inhibits HIF-1 Hypoxia-Inducible Factor Activity in a Negative Feedback Loop That Does Not Include vhl-1

Chuan Shen, Zhiyong Shao, Jo Anne Powell-Coffman

Genetics. 2006 Nov; 174(3): 1205–1214. doi: 10.1534/genetics.106.063594

PMCID:: PMC1667075

Abstract Article PDF–1.0M

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