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Select item 108757761.

Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling

Haoqing Li, Yingyu Liu, Fengyan Meng, Junan Chen, Xingfa Han

BMC Genomics. 2024; 25: 190. Published online 2024 Feb 19. doi: 10.1186/s12864-024-10107-6

PMCID:: PMC10875776

Abstract Article PDF–5.8M

Select item 107153162.

Lanosterol Synthase Prevents EMT During Lens Epithelial Fibrosis Via Regulating SREBP1

Pengjuan Ma, Jingqi Huang, Baoxin Chen, Mi Huang, Lang Xiong, Jieping Chen, Shan Huang, Yizhi Liu

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 12. Published online 2023 Dec 11. doi: 10.1167/iovs.64.15.12

PMCID:: PMC10715316

Abstract Article PDF–6.0M

Select item 100265963.

Early growth response-1 transcription factor promotes hepatic fibrosis and steatosis in long-term ethanol-fed Long-Evans rats

Zoltan Derdak, Kristine A. Villegas, Jack R. Wands

Liver Int. Author manuscript; available in PMC 2023 Mar 20.

Published in final edited form as: Liver Int. 2012 May; 32(5): 761–770. Published online 2012 Jan 31. doi: 10.1111/j.1478-3231.2012.02752.x

PMCID:: PMC10026596

Abstract Article PDF–1.3M

Select item 71817384.

Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment

Uk-Il Ju, Do-Won Jeong, Jieun Seo, Jun Bum Park, Jong-Wan Park, Kyung-Suk Suh, Jae Bum Kim, Yang-Sook Chun

Cell Death Dis. 2020 Apr; 11(4): 283. Published online 2020 Apr 24. doi: 10.1038/s41419-020-2472-6

PMCID:: PMC7181738

Abstract Article PDF–2.1M

Select item 67922155.

Down-regulated of SREBP-1 in circulating leukocyte is a risk factor for atherosclerosis: a case control study

Chunyan Peng, Pan Lei, Xiandong Li, Huaqiang Xie, Xiaowen Yang, Tao Zhang, Zheng Cao, Jicai Zhang

Lipids Health Dis. 2019; 18: 177. Published online 2019 Oct 14. doi: 10.1186/s12944-019-1125-1

PMCID:: PMC6792215

Abstract Article PDF–697K

Select item 66108116.

Effect of Nanoformulated Copper/Zinc Superoxide Dismutase on Chronic Ethanol-Induced Alterations in Liver and Adipose Tissue

Gopalakrishnan Natarajan, Curtis Perriotte-Olson, Carol A Casey, Terrence M. Donohue, Jr., Geoffrey A Talmon, Edward N Harris, Alexander V Kabanov, Viswanathan Saraswathi

Alcohol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Alcohol. 2019 Sep; 79: 71–79. Published online 2019 Jan 3. doi: 10.1016/j.alcohol.2018.12.005

PMCID:: PMC6610811

Abstract Article PDF–2.4M

Select item 61012177.

SREBP1 is required for the induction by glucose of pancreatic β-cell genes involved in glucose sensing

Frederique Diraison, Magalie A. Ravier, Sarah K. Richards, Richard M. Smith, Hitoshi Shimano, Guy A. Rutter

J Lipid Res. Author manuscript; available in PMC 2018 Aug 20.

Published in final edited form as: J Lipid Res. 2008 Apr; 49(4): 814–822. Published online 2008 Jan 4. doi: 10.1194/jlr.M700533-JLR200

PMCID:: PMC6101217

Abstract Article PDF–1.2M

Select item 60529328.

Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis

Ying-Bin Hu, Xin-Yu Liu, Wei Zhan

Drug Des Devel Ther. 2018; 12: 2213–2221. Published online 2018 Jul 16. doi: 10.2147/DDDT.S170518

PMCID:: PMC6052932

Abstract Article PDF–2.0M

Select item 60236089.

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver

Jing Tian, Jiaxi Wu, Xiang Chen, Tong Guo, Zhijian J Chen, Joseph L Goldstein, Michael S Brown

eLife. 2018; 7: e36826. Published online 2018 Jun 27. doi: 10.7554/eLife.36826

PMCID:: PMC6023608

Abstract Article PDF–1.7M

Select item 590762410.

Eicosapentaenoic Acid Improves Polycystic Ovary Syndrome in Rats via Sterol Regulatory Element-Binding Protein 1 (SREBP-1)/Toll-Like Receptor 4 (TLR4) Pathway

Yanting Wang, Jinying He, Jing Yang

Med Sci Monit. 2018; 24: 2091–2097. Published online 2018 Apr 8. doi: 10.12659/MSM.909098

PMCID:: PMC5907624

Abstract Article PDF–1.8M

Select item 585464211.

(–)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B

Wei Wang, Zheng-Zhu Zhang, Yan Wu, Ru-Qing Wang, Jin-Wu Chen, Jing Chen, Yan Zhang, Ya-Jun Chen, Ming Geng, Zhong-Dong Xu, Min Dai, Jin-Hua Li, Li-Long Pan

Front Pharmacol. 2018; 9: 195. Published online 2018 Mar 9. doi: 10.3389/fphar.2018.00195

Correction in:: Front Pharmacol. 2018; 9: 459.

PMCID:: PMC5854642

Abstract Article PDF–1.1M

Select item 549176612.

Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes

Natsumi Tajima-Shirasaki, Kiyo-aki Ishii, Hiroaki Takayama, Takayoshi Shirasaki, Hisakazu Iwama, Keita Chikamoto, Yoshiro Saito, Yasumasa Iwasaki, Atsushi Teraguchi, Fei Lan, Akihiro Kikuchi, Yumie Takeshita, Koji Murao, Seiichi Matsugo, Shuichi Kaneko, Hirofumi Misu, Toshinari Takamura

J Biol Chem. 2017 Jun 30; 292(26): 10791–10800. Published online 2017 May 2. doi: 10.1074/jbc.M116.747006

PMCID:: PMC5491766

Abstract Article PDF–539K

Select item 541675713.

Sterol Regulatory Element-Binding Proteins Are Regulators of the NIS Gene in Thyroid Cells

Robert Ringseis, Christine Rauer, Susanne Rothe, Denise K. Gessner, Lisa-Marie Schütz, Sebastian Luci, Gaiping Wen, Klaus Eder

Mol Endocrinol. May 1, 2013; 27(5): 781–800. Published online 2013 Mar 29. doi: 10.1210/me.2012-1269

PMCID:: PMC5416757

Abstract Article

Select item 537286114.

The Combination of Blueberry Juice and Probiotics Ameliorate Non-Alcoholic Steatohepatitis (NASH) by Affecting SREBP-1c/PNPLA-3 Pathway via PPAR-α

Tingting Ren, Juanjuan Zhu, Lili Zhu, Mingliang Cheng

Nutrients. 2017 Mar; 9(3): 198. Published online 2017 Feb 27. doi: 10.3390/nu9030198

PMCID:: PMC5372861

Abstract Article PDF–6.7M

Select item 537028915.

Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study

Luis M. Pérez-Belmonte, Inmaculada Moreno-Santos, Fernando Cabrera-Bueno, Gemma Sánchez-Espín, Daniel Castellano, Miguel Such, María G Crespo-Leiro, Fernando Carrasco-Chinchilla, Luis Alonso-Pulpón, Miguel López-Garrido, Amalio Ruiz-Salas, Víctor M. Becerra-Muñoz, Juan J. Gómez-Doblas, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro

Int J Med Sci. 2017; 14(3): 268–274. Published online 2017 Feb 23. doi: 10.7150/ijms.17821

PMCID:: PMC5370289

Abstract Article PDF–325K

Select item 496115116.

Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex

Jing Tian, Joseph L. Goldstein, Michael S. Brown

Proc Natl Acad Sci U S A. 2016 Jul 19; 113(29): 8182–8187. Published online 2016 Jul 5. doi: 10.1073/pnas.1608987113

PMCID:: PMC4961151

Abstract Article PDF–1.0M

Select item 476683417.

Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and NFκB in rodent diabetic liver and relationships to hyperlipidemia and insulin resistance

M. P. Sajan, M. L. Standaert, J. Rivas, A. Miura, Y. Kanoh, J. Soto, C.M. Taniguchi, C.R. Kahn, R.V. Farese

Diabetologia. Author manuscript; available in PMC 2016 Feb 25.

Published in final edited form as: Diabetologia. 2009 Jun; 52(6): 1197–1207. Published online 2009 Apr 9. doi: 10.1007/s00125-009-1336-5

PMCID:: PMC4766834

Abstract Article PDF–1.1M

Select item 471851018.

Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation

Qingming Dong, Francesco Giorgianni, Sarka Beranova-Giorgianni, Xiong Deng, Robert N. O'Meally, Dave Bridges, Edwards A. Park, Robert N. Cole, Marshall B. Elam, Rajendra Raghow

Biosci Rep. 2016 Feb; 36(1): e00284. Prepublished online 2015 Nov 20. Published online 2016 Jan 15. doi: 10.1042/BSR20150234

PMCID:: PMC4718510

Abstract Article PDF–1.6M

Select item 471199519.

Identification of miR-148a as a novel regulator of cholesterol metabolism

Leigh Goedeke, Noemi Rotllan, Alberto Canfrán-Duque, Juan F. Aranda, Cristina M. Ramírez, Elisa Araldi, Chin-Sheng Lin, Norma N. Anderson, Alexandre Wagschal, Rafael de Cabo, Jay D. Horton, Miguel A. Lasunción, Anders M. Näär, Yajaira Suárez, Carlos Fernández-Hernando

Nat Med. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Nat Med. 2015 Nov; 21(11): 1280–1289. Published online 2015 Oct 5. doi: 10.1038/nm.3949

PMCID:: PMC4711995

Abstract Article PDF–1.4M

Select item 457892720.

Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis

Haiyan Zhang, Yihang Li, Jie Hu, Wen-Jun Shen, Madhurima Singh, Xiaoming Hou, Alex Bittner, Stefanie Bittner, Yuan Cortez, Juveria Tabassum, Fredric B. Kraemer, Salman Azhar

PLoS One. 2015; 10(9): e0138203. Published online 2015 Sep 22. doi: 10.1371/journal.pone.0138203

PMCID:: PMC4578927

Abstract Article PDF–1.4M

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