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Select item 104998211.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 80929602.

Overexpression of the Immunoreceptor CD300f Has a Neuroprotective Role in a Model of Acute Brain Injury

Hugo Peluffo, Daniela Alí‐Ruiz, Aroa Ejarque‐Ortíz, Victor Heras‐Alvarez, Emma Comas‐Casellas, Agueda Martínez‐Barriocanal, Andres Kamaid, Damiana Alvarez‐Errico, Maria Luciana Negro, Natalia Lago, Simó Schwartz Jr, Antonio Villaverde, Joan Sayós

Brain Pathol. 2012 May; 22(3): 318–328. Published online 2011 Oct 31. doi: 10.1111/j.1750-3639.2011.00537.x

PMCID:: PMC8092960

Abstract Article PDF–2.2M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71043694.

CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness

Natalia Lago, Fernanda N. Kaufmann, María Luciana Negro-Demontel, Daniela Alí-Ruiz, Gabriele Ghisleni, Natalia Rego, Andrea Arcas-García, Nathalia Vitureira, Karen Jansen, Luciano M. Souza, Ricardo A. Silva, Diogo R. Lara, Bruno Pannunzio, Juan Andrés Abin-Carriquiry, Jesús Amo-Aparicio, Celia Martin-Otal, Hugo Naya, Dorian B. McGavern, Joan Sayós, Rubèn López-Vales, Manuella P. Kaster, Hugo Peluffo

Proc Natl Acad Sci U S A. 2020 Mar 24; 117(12): 6651–6662. Published online 2020 Mar 9. doi: 10.1073/pnas.1911816117

PMCID:: PMC7104369

Abstract Article PDF–1.7M

Select item 69277545.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 60777226.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 56488727.

Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis

Águeda Martínez-Barriocanal, Andrea Arcas-García, Miriam Magallon-Lorenz, Aroa Ejarque-Ortíz, María Luciana Negro-Demontel, Emma Comas-Casellas, Simo Schwartz, Jr., Sunny Malhotra, Xavier Montalban, Hugo Peluffo, Margarita Martín, Manuel Comabella, Joan Sayós

Sci Rep. 2017; 7: 13544. Published online 2017 Oct 19. doi: 10.1038/s41598-017-12881-8

PMCID:: PMC5648872

Abstract Article PDF–3.7M

Select item 38420258.

A Multi-Ethnic Meta-Analysis of Genome-Wide Association Studies in Over 100,000 Subjects Identifies 23 Fibrinogen-Associated Loci but no Strong Evidence of a Causal Association between Circulating Fibrinogen and Cardiovascular Disease

Maria Sabater-Lleal, Jie Huang, Daniel Chasman, Silvia Naitza, Abbas Dehghan, Andrew D Johnson, Alexander Teumer, Alex P Reiner, Lasse Folkersen, Saonli Basu, Alicja R Rudnicka, Stella Trompet, Anders Mälarstig, Jens Baumert, Joshua C. Bis, Xiuqing Guo, Jouke J Hottenga, So-Youn Shin, Lorna M Lopez, Jari Lahti, Toshiko Tanaka, Lisa R Yanek, Tiphaine Oudot-Mellakh, James F Wilson, Pau Navarro, Jennifer E Huffman, Tatijana Zemunik, Susan Redline, Reena Mehra, Drazen Pulanic, Igor Rudan, Alan F Wright, Ivana Kolcic, Ozren Polasek, Sarah H Wild, Harry Campbell, J David Curb, Robert Wallace, Simin Liu, Charles B. Eaton, Diane M. Becker, Lewis C. Becker, Stefania Bandinelli, Katri Räikkönen, Elisabeth Widen, Aarno Palotie, Myriam Fornage, David Green, Myron Gross, Gail Davies, Sarah E Harris, David C Liewald, John M Starr, Frances M.K. Williams, P.J. Grant, Timothy D. Spector, Rona J Strawbridge, Angela Silveira, Bengt Sennblad, Fernando Rivadeneira, Andre G Uitterlinden, Oscar H Franco, Albert Hofman, Jenny van Dongen, G Willemsen, Dorret I Boomsma, Jie Yao, Nancy Swords Jenny, Talin Haritunians, Barbara McKnight, Thomas Lumley, Kent D Taylor, Jerome I Rotter, Bruce M Psaty, Annette Peters, Christian Gieger, Thomas Illig, Anne Grotevendt, Georg Homuth, Henry Völzke, Thomas Kocher, Anuj Goel, Maria Grazia Franzosi, Udo Seedorf, Robert Clarke, Maristella Steri, Kirill V Tarasov, Serena Sanna, David Schlessinger, David J Stott, Naveed Sattar, Brendan M Buckley, Ann Rumley, Gordon D Lowe, Wendy L McArdle, Ming-Huei Chen, Geoffrey H Tofler, Jaejoon Song, Eric Boerwinkle, Aaron R. Folsom, Lynda M. Rose, Anders Franco-Cereceda, Martina Teichert, M Arfan Ikram, Thomas H Mosley, Steve Bevan, Martin Dichgans, Peter M. Rothwell, Cathie L M Sudlow, Jemma C. Hopewell, John C. Chambers, Danish Saleheen, Jaspal S. Kooner, John Danesh, Christopher P Nelson, Jeanette Erdmann, Muredach P. Reilly, Sekar Kathiresan, Heribert Schunkert, Pierre-Emmanuel Morange, Luigi Ferrucci, Johan G Eriksson, David Jacobs, Ian J Deary, Nicole Soranzo, Jacqueline CM Witteman, Eco JC de Geus, Russell P. Tracy, Caroline Hayward, Wolfgang Koenig, Francesco Cucca, J Wouter Jukema, Per Eriksson, Sudha Seshadri, Hugh S. Markus, Hugh Watkins, Nilesh J Samani, VTE consortium, STROKE Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), C4D consortium, CARDIoGRAM consortium, Henri Wallaschofski, Nicholas L. Smith, David Tregouet, Paul M. Ridker, Weihong Tang, David P. Strachan, Anders Hamsten, Christopher J. O’Donnell

Circulation. Author manuscript; available in PMC 2014 Sep 17.

Published in final edited form as: Circulation. 2013 Sep 17; 128(12): 10.1161/CIRCULATIONAHA.113.002251. Published online 2013 Aug 22. doi: 10.1161/CIRCULATIONAHA.113.002251

PMCID:: PMC3842025

Abstract Article PDF–917K

Select item 33742769.

Synthetic peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling through activation of SHP and/or PI3K

S-M Lee, K Suk, W-H Lee

Clin Exp Immunol. 2012 Mar; 167(3): 438–446. doi: 10.1111/j.1365-2249.2011.04528.x

PMCID:: PMC3374276

Abstract Article PDF–766K

Select item 332297010.

Cloning and Characterization of CD300d, a Novel Member of the Human CD300 Family of Immune Receptors

Emma Comas-Casellas, Águeda Martínez-Barriocanal, Francesc Miró, Aroa Ejarque-Ortiz, Simo Schwartz, Jr., Margarita Martín, Joan Sayós

J Biol Chem. 2012 Mar 23; 287(13): 9682–9693. Published online 2012 Jan 30. doi: 10.1074/jbc.M111.279224

PMCID:: PMC3322970

Abstract Article PDF–2.9M

Select item 331104511.

CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines

Eun-Ju Kim, Sang-Min Lee, Kyoungho Suk, Won-Ha Lee

Immunology. 2012 Mar; 135(3): 226–235. doi: 10.1111/j.1365-2567.2011.03528.x

PMCID:: PMC3311045

Abstract Article PDF–546K

Select item 319082612.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300990614.

CD300 Heterocomplexes, a New and Family-restricted Mechanism for Myeloid Cell Signaling Regulation

Águeda Martínez-Barriocanal, Emma Comas-Casellas, Simo Schwartz, Jr, Margarita Martín, Joan Sayós

J Biol Chem. 2010 Dec 31; 285(53): 41781–41794. Published online 2010 Oct 19. doi: 10.1074/jbc.M110.140889

PMCID:: PMC3009906

Abstract Article PDF–2.1M

Select item 296296815.

Immune receptor expressed on myeloid cells 1 (IREM-1) inhibits B cell activation factor (BAFF)-mediated inflammatory regulation of THP-1 cells through modulation of the activities of extracellular regulated kinase (ERK)

S-M Lee, Y-P Nam, K Suk, W-H Lee

Clin Exp Immunol. 2010 Sep; 161(3): 504–511. doi: 10.1111/j.1365-2249.2010.04211.x

PMCID:: PMC2962968

Abstract Article PDF–458K

Select item 274951316.

Multiple Novel Loci, Including Those Related to Crohn’s Disease, Psoriasis and Inflammation, Identified in a Genome-Wide Association Study of Fibrinogen in 17,686 Women: the Women’s Genome Health Study

Jacqueline S. Danik, Guillaume Pare, Daniel I. Chasman, Robert Y.L. Zee, David J. Kwiatkowski, Alex Parker, Joseph P. Miletich, Paul M Ridker

Circ Cardiovasc Genet. Author manuscript; available in PMC 2010 Apr 1.

Published in final edited form as: Circ Cardiovasc Genet. 2009 Apr; 2(2): 134–141. Published online 2009 Feb 12. doi: 10.1161/CIRCGENETICS.108.825273

PMCID:: PMC2749513

Abstract Article PDF–423K

Select item 228655117.

Signal peptide prediction based on analysis of experimentally verified cleavage sites

Zemin Zhang, William J. Henzel

Protein Sci. 2004 Oct; 13(10): 2819–2824. doi: 10.1110/ps.04682504

PMCID:: PMC2286551

Abstract Article PDF–125K

Select item 135612918.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 51531620.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Abstract Article PDF–181K

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