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Select item 115159181.

Hypoxic Upregulation of IER2 Increases Paracrine GMFG Signaling of Endoplasmic Reticulum Stress‐CAF to Promote Chordoma Progression via Targeting ITGB1

Tao‐Lan Zhang, Bo‐Wen Zheng, Chao Xia, Peng‐Fei Wu, Bo‐Yv Zheng, Ling‐Xiang Jiang, Jing Li, Guo‐Hua Lv, Hong Zhou, Wei Huang, Ming‐Xiang Zou

Adv Sci (Weinh) 2024 Oct; 11(40): 2405421. Published online 2024 Aug 29. doi: 10.1002/advs.202405421

PMCID:: PMC11515918

Abstract Article PDF–15M

Select item 114638572.

α₉β₁ integrin & its ligands as new potential biomarkers in FMF

Pınar Ellergezen, Belkıs Nihan Coşkun, Zeynep Yılmaz Bozkurt, Gülce Sevdar Çeçen, Harun Ağca, Yavuz Pehlivan, Hüseyin Ediz Dalkılıç, Sinan Çavun, Yusuf Berkcan Yanar

Indian J Med Res. 2024 Jul; 160(1): 102–108. Published online 2024 Sep 30. doi: 10.25259/ijmr_985_23

PMCID:: PMC11463857

Abstract Article PDF–367K

Select item 114472563.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 114363784.

The VLA-4 integrin is constitutively active in circulating chronic lymphocytic leukemia cells via BCR autonomous signaling: a novel anchor-independent mechanism exploiting soluble blood-borne ligands

Erika Tissino, Annalisa Gaglio, Antonella Nicolò, Federico Pozzo, Tamara Bittolo, Francesca Maria Rossi, Riccardo Bomben, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Anna Maria Zimbo, Giulia Ianna, Guido Capasso, Gabriela Forestieri, Riccardo Moia, Moumita Datta, Andrea Härzschel, Jacopo Olivieri, Giovanni D’Arena, Luca Laurenti, Francesco Zaja, Annalisa Chiarenza, Giuseppe A. Palumbo, Enrica Antonia Martino, Massimo Gentile, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, Roberta Laureana, Maria Ilaria Del Principe, Palash C. Maity, Hassan Jumaa, Tanja Nicole Hartmann, Antonella Zucchetto, Valter Gattei

Leukemia. 2024; 38(10): 2127–2140. Published online 2024 Aug 14. doi: 10.1038/s41375-024-02376-7

PMCID:: PMC11436378

Abstract Article PDF–3.0M

Select item 114289155.

Tetraspanin 3 promotes NSCLC cell proliferation via regulation of β1 integrin intracellular recycling

Yao Zhang, Chenglong Wang, Yitong Xu, Hongbo Su

Cell Mol Biol Lett. 2024; 29: 124. Published online 2024 Sep 27. doi: 10.1186/s11658-024-00639-w

PMCID:: PMC11428915

Abstract Article PDF–6.2M

Select item 113735996.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113159297.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 112969148.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112099359.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 1117233910.

ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins

Kasper J. Mygind, Denise Nikodemus, Sebastian Gnosa, Ramya Kweder, Nicolai J. Wewer Albrechtsen, Marie Kveiborg, Janine T. Erler, Reidar Albrechtsen

Int J Mol Sci. 2024 Jun; 25(11): 5871. Published online 2024 May 28. doi: 10.3390/ijms25115871

PMCID:: PMC11172339

Abstract Article PDF–2.5M

Select item 1117180111.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 1115781912.

Integrin αVβ1-activated PYK2 promotes the progression of non-small-cell lung cancer via the STAT3-VGF axis

Zhengyan Wu, Min Jiao, Chenying Shu, Saiqun Zhang, Jiajia Wang, Jianhong Pu, Jianjie Zhu, Yuanyuan Zeng, Yehan Zhu, Zeyi Liu

Cell Commun Signal. 2024; 22: 313. Published online 2024 Jun 6. doi: 10.1186/s12964-024-01639-1

PMCID:: PMC11157819

Abstract Article PDF–10M

Select item 1114853713.

ACSL4-Mediated Membrane Phospholipid Remodeling Induces Integrin β1 Activation to Facilitate Triple-Negative Breast Cancer Metastasis

Yuxiang Qiu, Xing Wang, Yan Sun, Ting Jin, Rui Tang, Xinyue Zhou, Ming Xu, Yubi Gan, Rui Wang, Haojun Luo, Manran Liu, Xi Tang

Cancer Res. 2024 Jun 4; 84(11): 1856–1871. Published online 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-2491

PMCID:: PMC11148537

Abstract Article PDF–29M

Select item 1114193514.

Blocking the angiopoietin-2–dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis

Lydia Meder, Charlotte Isabelle Orschel, Christoph Julius Otto, Mirjam Koker, Johannes Brägelmann, Meryem S. Ercanoglu, Sabrina Dähling, Anik Compes, Carolin Selenz, Marieke Nill, Felix Dietlein, Alexandra Florin, Marie-Lisa Eich, Sven Borchmann, Margarete Odenthal, Raquel Blazquez, Frank Hilberg, Florian Klein, Michael Hallek, Reinhard Büttner, H. Christian Reinhardt, Roland T. Ullrich

JCI Insight. 2024 May 22; 9(10): e166402. Published online 2024 May 22. doi: 10.1172/jci.insight.166402

PMCID:: PMC11141935

Abstract Article PDF–6.7M

Select item 1108605215.

Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells

Md Saimon Mia, Delowar Hossain, Emerson Woodbury, Sean Kelleher, Riya. J. Palamuttam, Reena Rao, Preston Steen, Yagna PR Jarajapu, Sijo Mathew

Eur J Cell Biol. Author manuscript; available in PMC 2024 May 10.

Published in final edited form as: Eur J Cell Biol. 2023 Jun; 102(2): 151316. Published online 2023 Apr 18. doi: 10.1016/j.ejcb.2023.151316

PMCID:: PMC11086052

Abstract Article PDF–1.9M

Select item 1106340216.

Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT

Nilesh Pandey, Harpreet Kaur, Mehul R. Chorawala, Sumit Kumar Anand, Lakshmi Chandaluri, Megan E. Butler, Richa Aishwarya, Shiva J. Gaddam, Xinggui Shen, Mabruka Alfaidi, Jian Wang, Xiaolu Zhang, Kavitha Beedupalli, Md. Shenuarin Bhuiyan, Mohammad Alfrad Nobel Bhuiyan, Prabandh Buchhanolla, Prashant Rai, Rahul Shah, Himanshu Chokhawala, J. Dedrick Jordan, Tarek Magdy, A. Wayne Orr, Karen Y. Stokes, Oren Rom, Nirav Dhanesha

Blood Adv. 2024 May 14; 8(9): 2104–2117. Published online 2024 Mar 27. doi: 10.1182/bloodadvances.2023012282

PMCID:: PMC11063402

Abstract Article PDF–4.8M

Select item 1105524017.

Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease

Junhua Huang, Chuanmei Zhao, Shuwan Zhang

BMC Pediatr. 2024; 24: 285. Published online 2024 Apr 27. doi: 10.1186/s12887-024-04766-3

PMCID:: PMC11055240

Abstract Article PDF–2.2M

Select item 1103423518.

β1 Integrin triggering affects leukemic cell line sensitivity to natural killer cells

Gonzalo Rubio, Xabier Ferez, Ana Mora, Jesus Galvez, Antonio Chicano, Pilar Garcia-Peñarrubia

Cancer Immunol Immunother. 2002 May; 51(3): 130–138. Published online 2002 Feb 28. doi: 10.1007/s00262-002-0264-8

PMCID:: PMC11034235

Abstract Article PDF–182K

Select item 1099027719.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 1096468320.

A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

Mingming Xue, Lingyu Xing, Yilin Yang, Mian Shao, Fengqing Liao, Feixiang Xu, Yumei Chen, Sheng Wang, Bin Chen, Chenling Yao, Guorong Gu, Chaoyang Tong

BMC Cardiovasc Disord. 2024; 24: 180. Published online 2024 Mar 26. doi: 10.1186/s12872-024-03778-2

PMCID:: PMC10964683

Abstract Article PDF–4.4M

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