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Select item 109871221.

YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD‐L1/VEGFA Axis

Jingyuan Wen, Lin Xue, Yi Wei, Junnan Liang, Wenlong Jia, Tuying Yong, Liang Chu, Han Li, Shenqi Han, Jingyu Liao, Zeyu Chen, Yiyang Liu, Qiumeng Liu, Zeyang Ding, Huifang Liang, Lu Gan, Xiaoping Chen, Zhao Huang, Bixiang Zhang

Adv Sci (Weinh) 2024 Apr; 11(13): 2307242. Published online 2024 Jan 21. doi: 10.1002/advs.202307242

PMCID:: PMC10987122

Abstract Article PDF–7.4M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104998213.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 99870994.

E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function

Yi Wei, Shenqi Han, Jingyuan Wen, Jingyu Liao, Junnan Liang, Jingjing Yu, Xiaoping Chen, Shuai Xiang, Zhao Huang, Bixiang Zhang

J Biomed Sci. 2023; 30: 17. Published online 2023 Mar 6. doi: 10.1186/s12929-023-00909-3

PMCID:: PMC9987099

Abstract Article PDF–8.4M

Select item 92543785.

ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2

Ming-Chuang Sun, Kang Fang, Zhao-Xing Li, Yuan Chu, Ai-Ping Xu, Zi-Ying Zhao, Zhu-Yun Leng, Yun-Wei Zhang, Ze-Hua Zhang, Li Zhang, Tao Chen, Mei-Dong Xu

Int J Med Sci. 2022; 19(6): 1072–1081. Published online 2022 Jun 21. doi: 10.7150/ijms.71892

PMCID:: PMC9254378

Abstract Article PDF–1.9M

Select item 89142836.

Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion

Jones K. Ofori, Alexandros Karagiannopoulos, Mototsugu Nagao, Efraim Westholm, Shaima Ramadan, Anna Wendt, Jonathan L.S. Esguerra, Lena Eliasson

Diabetes. 2022 Feb; 71(2): 275–284. Published online 2021 Nov 9. doi: 10.2337/db21-0077

PMCID:: PMC8914283

Abstract Article PDF–1.4M

Select item 88288957.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 85700118.

Biological and prognostic value of ETV5 in high-grade serous ovarian cancer

Lu Zhang, Ruiting Fu, Ping Liu, Lijun Wang, Weihua Liang, Hong Zou, Wei Jia, Lin Tao

J Ovarian Res. 2021; 14: 149. Published online 2021 Nov 4. doi: 10.1186/s13048-021-00899-6

PMCID:: PMC8570011

Abstract Article PDF–1.9M

Select item 85563369.

Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity

Ren-Dong Hu, Wen Zhang, Liang Li, Zu-Qi Zuo, Min Ma, Jin-Fen Ma, Ting-Ting Yin, Cai-Yue Gao, Shu-Han Yang, Zhi-Bin Zhao, Zi-Jun Li, Gui-Bin Qiao, Zhe-Xiong Lian, Kun Qu

Cell Death Dis. 2021 Nov; 12(11): 1023. Published online 2021 Oct 29. doi: 10.1038/s41419-021-04308-0

PMCID:: PMC8556336

Abstract Article PDF–4.4M

Select item 822039110.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808782212.

The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression

Yi Peng, Haoran Feng, Changgang Wang, Zijia Song, Yaqi Zhang, Kun Liu, Xi Cheng, Ren Zhao

Cell Death Dis. 2021 May; 12(5): 427. Published online 2021 Apr 30. doi: 10.1038/s41419-021-03717-5

PMCID:: PMC8087822

Abstract Article PDF–2.0M

Select item 808063113.

IP₆-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion

Hong Lin, Yuan Yan, Yifan Luo, Wing Yan So, Xiayun Wei, Xiaozhe Zhang, Xiaoli Yang, Jun Zhang, Yang Su, Xiuyan Yang, Bobo Zhang, Kangjun Zhang, Nan Jiang, Billy Kwok Chong Chow, Weiping Han, Fengchao Wang, Feng Rao

Nat Commun. 2021; 12: 2461. Published online 2021 Apr 28. doi: 10.1038/s41467-021-22941-3

PMCID:: PMC8080631

Abstract Article PDF–3.1M

Select item 800904814.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 738018215.

ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite ETS/E-box motifs

Fan Zhang, Shuwen Wang, Jiyue Zhu

J Biol Chem. 2020 Jul 17; 295(29): 10062–10075. Published online 2020 Jun 9. doi: 10.1074/jbc.RA119.012130

PMCID:: PMC7380182

Abstract Article PDF–2.5M

Select item 695922616.

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

Liselot M. Mus, Irina Lambertz, Shana Claeys, Candy Kumps, Wouter Van Loocke, Christophe Van Neste, Ganesh Umapathy, Marica Vaapil, Christoph Bartenhagen, Genevieve Laureys, Olivier De Wever, Daniel Bexell, Matthias Fischer, Bengt Hallberg, Johannes Schulte, Bram De Wilde, Kaat Durinck, Geertrui Denecker, Katleen De Preter, Frank Speleman

Sci Rep. 2020; 10: 218. Published online 2020 Jan 14. doi: 10.1038/s41598-019-57076-5

PMCID:: PMC6959226

Abstract Article PDF–2.3M

Select item 645094417.

ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer

Erica di Martino, Olivia Alder, Carolyn D. Hurst, Margaret A. Knowles

Sci Rep. 2019; 9: 5740. Published online 2019 Apr 5. doi: 10.1038/s41598-018-36456-3

PMCID:: PMC6450944

Abstract Article PDF–1.5M

Select item 607772218.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 599210419.

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins

James E. Tomkins, Sybille Dihanich, Alexandra Beilina, Raffaele Ferrari, Nicolò Ilacqua, Mark R. Cookson, Patrick A. Lewis, Claudia Manzoni

Proteomics. 2018 May; 18(10): 1700444. Published online 2018 Apr 17. doi: 10.1002/pmic.201700444

PMCID:: PMC5992104

Abstract Article PDF–1.2M

Select item 596375920.

Graph complexity analysis identifies an ETV5 tumor-specific network in human and murine low-grade glioma

Yuan Pan, Christina Duron, Erin C. Bush, Yu Ma, Peter A. Sims, David H. Gutmann, Ami Radunskaya, Johanna Hardin

PLoS One. 2018; 13(5): e0190001. Published online 2018 May 22. doi: 10.1371/journal.pone.0190001

PMCID:: PMC5963759

Abstract Article PDF–4.9M

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