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Select item 111569111.

m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation

Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I. Roumeliotis, Jyoti S. Choudhary, Anob M. Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos

Nat Commun. 2024; 15: 4819. Published online 2024 Jun 6. doi: 10.1038/s41467-024-49139-7

PMCID:: PMC11156911

Abstract Article PDF–3.5M

Select item 109489882.

LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1

Zhenghao Huang, Fan Shen, Jingwen Chen, Bumin Xie, Xi Chen, Yang Zhao, Shuo Chen

J Gynecol Oncol. 2024 Mar; 35(2): e21. Published online 2023 Nov 21. doi: 10.3802/jgo.2024.35.e21

PMCID:: PMC10948988

Abstract Article PDF–3.3M

Select item 109208423.

METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability

Xuefei Sun, Xiujiao Meng, Yu Piao, Shaojie Dong, Qianqian Dong

Int J Med Sci. 2024; 21(4): 664–673. Published online 2024 Feb 4. doi: 10.7150/ijms.90485

PMCID:: PMC10920842

Abstract Article PDF–3.5M

Select item 108596054.

Tumor suppressive function of IGF2BP1 in gastric cancer through decreasing MYC

Ning Ding, Guodong Cao, Zhuo Wang, Shengjun Xu, Wenwen Chen

Cancer Sci. 2024 Feb; 115(2): 427–438. Published online 2023 Dec 19. doi: 10.1111/cas.16047

PMCID:: PMC10859605

Abstract Article PDF–15M

Select item 107999035.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 107649586.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106259307.

m⁶A modification of AC026356.1 facilitates hepatocellular carcinoma progression by regulating the IGF2BP1-IL11 axis

Huamei Wei, Jinhun Yang, Rongzhou Lu, Yanyan Huang, Zheng Huang, Lizheng Huang, Min Zeng, Yunyu Wei, Zuoming Xu, Wenchuan Li, Jian Pu

Sci Rep. 2023; 13: 19124. Published online 2023 Nov 5. doi: 10.1038/s41598-023-45449-w

PMCID:: PMC10625930

Abstract Article PDF–4.5M

Select item 106176738.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105658769.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1038535610.

IGF2BP1—An Oncofetal RNA-Binding Protein Fuels Tumor Virus Propagation

Markus Glaß, Stefan Hüttelmaier

Viruses. 2023 Jul; 15(7): 1431. Published online 2023 Jun 24. doi: 10.3390/v15071431

PMCID:: PMC10385356

Abstract Article PDF–738K

Select item 1024380711.

MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity

Lydie Naulé, Alessandra Mancini, Sidney A. Pereira, Brandon M. Gassaway, John R. Lydeard, John C. Magnotto, Han Kyeol Kim, Joy Liang, Cynara Matos, Steven P. Gygi, Florian T. Merkle, Rona S. Carroll, Ana Paula Abreu, Ursula B. Kaiser

JCI Insight. 2023 Apr 24; 8(8): e164178. Published online 2023 Apr 24. doi: 10.1172/jci.insight.164178

PMCID:: PMC10243807

Abstract Article PDF–9.5M

Select item 1023505012.

RPS15 interacted with IGF2BP1 to promote esophageal squamous cell carcinoma development via recognizing m⁶A modification

Yahui Zhao, Yang Li, Rui Zhu, Riyue Feng, Heyang Cui, Xiao Yu, Furong Huang, Ruixiang Zhang, Xiankai Chen, Lei Li, Yinghui Chen, Yuhao Liu, Jinhua Wang, Guanhua Du, Zhihua Liu

Signal Transduct Target Ther. 2023; 8: 224. Published online 2023 Jun 2. doi: 10.1038/s41392-023-01428-1

PMCID:: PMC10235050

Abstract Article PDF–6.3M

Select item 1022626013.

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

Sven Hagemann, Danny Misiak, Jessica L. Bell, Tommy Fuchs, Marcell I. Lederer, Nadine Bley, Monika Hämmerle, Ehab Ghazy, Wolfgang Sippl, Johannes H. Schulte, Stefan Hüttelmaier

Mol Cancer. 2023; 22: 88. Published online 2023 May 29. doi: 10.1186/s12943-023-01792-0

PMCID:: PMC10226260

Abstract Article PDF–6.5M

Select item 1015862414.

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen

FASEB Bioadv. 2023 May; 5(5): 183–198. Published online 2023 Feb 21. doi: 10.1096/fba.2022-00115

PMCID:: PMC10158624

Abstract Article PDF–7.2M

Select item 1015485215.

Feedforward loop between IMP1 and YAP/TAZ promotes tumorigenesis and malignant progression in glioblastoma

Jia Yang, Xujia Wu, Jia Wang, Xing Guo, Junju Chen, Xuesong Yang, Jian Zhong, Xixi Li, Zhong Deng

Cancer Sci. 2023 May; 114(5): 2053–2062. Published online 2023 Mar 1. doi: 10.1111/cas.15636

PMCID:: PMC10154852

Abstract Article PDF–23M

Select item 1015161516.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1013893117.

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter

Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041

PMCID:: PMC10138931

Abstract Article PDF–4.0M

Select item 1012400618.

A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA

Pei Lu, Jie Yang, Mao Li, Shanshan Wen, Tianzhe Zhang, Chenchao Yan, Ran Liu, Yu Xiao, Xinghuan Wang, Wei Jiang

Genome Biol. 2023; 24: 92. Published online 2023 Apr 24. doi: 10.1186/s13059-023-02925-w

PMCID:: PMC10124006

Abstract Article PDF–5.9M

Select item 1007983319.

PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer

Yunxing Shi, Yi Niu, Yichuan Yuan, Kai Li, Chengrui Zhong, Zhiyu Qiu, Keren Li, Zhu Lin, Zhiwen Yang, Dinglan Zuo, Jiliang Qiu, Wei He, Chenwei Wang, Yadi Liao, Guocan Wang, Yunfei Yuan, Binkui Li

Nat Commun. 2023; 14: 1932. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37542-5

PMCID:: PMC10079833

Abstract Article PDF–3.5M

Select item 1006958420.

ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers

Zheng-Zheng Yu, Yun-Ya Liu, Wei Zhu, Ding Xiao, Wei Huang, Shan-Shan Lu, Hong Yi, Ting Zeng, Xue-Ping Feng, Li Yuan, Jie-Ya Qiu, Di Wu, Qi Wen, Jian-Hua Zhou, Wei Zhuang, Zhi-Qiang Xiao

J Immunother Cancer. 2023; 11(3): e006345. Published online 2023 Mar 31. doi: 10.1136/jitc-2022-006345