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Select item 100590251.

Secretory Phospholipase A2 and Interleukin-6 Levels as Predictive Markers of the Severity and Outcome of Patients with COVID-19 Infections

Stanislav Urazov, Alexandr Chernov, Oleg Popov, Natalya Klenkova, Natalya Sushentseva, Irina Polkovnikova, Svetlana Apalko, Kseniya Kislyuk, Dragana Pavlovich, Andrey Ivanov, Sergey Shcherbak

Int J Mol Sci. 2023 Mar; 24(6): 5540. Published online 2023 Mar 14. doi: 10.3390/ijms24065540

PMCID:: PMC10059025

Abstract Article PDF–3.0M

Select item 98451492.

Interplay between C1-inhibitor and group IIA secreted phospholipase A₂ impairs their respective function

Anne Lise Ferrara, Maria Bova, Angelica Petraroli, Daniela Marasco, Christine Payré, Sara Fortuna, Francesco Palestra, Renato Ciardi, Gianni Marone, Giuseppe Spadaro, Gérard Lambeau, Stefania Loffredo

Immunol Res. 2023; 71(1): 70–82. Published online 2022 Nov 17. doi: 10.1007/s12026-022-09331-7

PMCID:: PMC9845149

Abstract Article PDF–1.5M

Select item 97725583.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 95704064.

PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation

Mingquan Zhang, Rong Xiang, Christophe Glorieux, Peng Huang

Int J Mol Sci. 2022 Oct; 23(19): 11721. Published online 2022 Oct 3. doi: 10.3390/ijms231911721

PMCID:: PMC9570406

Abstract Article PDF–3.4M

Select item 89318855.

Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma

EVANGELOS FALIDAS, EIRINI KITSIOULI, DESPOINA SPYROPOULOU, EVANGELOS TSIAMBAS, ASIMINA KALOGIROU, GEORGE TSOUVELAS, STYLIANOS PAPADOPOULOS, MICHAIL MITSIS, MARILENA LEKKA, SOFIANIKI MASTRONIKOLI, DIMITRIOS PESCHOS, ODYSSEAS DIMAS, KONSTANTINOS VLACHOS

In Vivo. 2022 Mar-Apr; 36(2): 738–742. Published online 2022 Mar 3. doi: 10.21873/invivo.12760

PMCID:: PMC8931885

Abstract Article PDF–749K

Select item 87155976.

Elevated lipoprotein(a) and lipoprotein-associated phospholipase A₂ are associated with unfavorable functional outcomes in patients with ischemic stroke

Xue Jiang, Jie Xu, Xiwa Hao, Jing Xue, Ke Li, Aoming Jin, Jinxi Lin, Xia Meng, Lemin Zheng, Yongjun Wang

J Neuroinflammation. 2021; 18: 307. Published online 2021 Dec 28. doi: 10.1186/s12974-021-02359-w

PMCID:: PMC8715597

Abstract Article PDF–961K

Select item 85515427.

Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A₂s

Daiki Hayashi, Varnavas D. Mouchlis, Edward A. Dennis

J Lipid Res. 2021; 62: 100113. Published online 2021 Aug 30. doi: 10.1016/j.jlr.2021.100113

PMCID:: PMC8551542

Abstract Article PDF–2.0M

Select item 84837528.

Group IIA secreted phospholipase A₂ is associated with the pathobiology leading to COVID-19 mortality

Justin M. Snider, Jeehyun Karen You, Xia Wang, Ashley J. Snider, Brian Hallmark, Manja M. Zec, Michael C. Seeds, Susan Sergeant, Laurel Johnstone, Qiuming Wang, Ryan Sprissler, Tara F. Carr, Karen Lutrick, Sairam Parthasarathy, Christian Bime, Hao Helen Zhang, Chiara Luberto, Richard R. Kew, Yusuf A. Hannun, Stefano Guerra, Charles E. McCall, Guang Yao, Maurizio Del Poeta, Floyd H. Chilton

J Clin Invest. 2021 Oct 1; 131(19): e149236. Published online 2021 Oct 1. doi: 10.1172/JCI149236

PMCID:: PMC8483752

Abstract Article PDF–3.2M

Select item 81283089.

A novel prognosis prediction model, including cytotoxic T lymphocyte‐associated antigen‐4, ischemia‐modified albumin, lipoprotein‐associated phospholipase A2, glial fibrillary acidic protein, and homocysteine, for ischemic stroke in the Chinese hypertensive population

Jin Ma, Likui Shen, Lei Bao, Hua Yuan, Yingxin Wang, Hua Liu, Qiang Wang

J Clin Lab Anal. 2021 May; 35(5): e23756. Published online 2021 Mar 18. doi: 10.1002/jcla.23756

PMCID:: PMC8128308

Abstract Article PDF–1.1M

Select item 758396910.

Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A₂

Ryung Rae Kim, Zheng Chen, Timothy J. Mann, Karine Bastard, Kieran F. Scott, W. Bret Church

Molecules. 2020 Oct; 25(19): 4459. Published online 2020 Sep 28. doi: 10.3390/molecules25194459

PMCID:: PMC7583969

Abstract Article PDF–2.7M

Select item 709765111.

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A₂

R.W. Schevitz, N.J. Bach, D.G. Carlson, N.Y. Chirgadze, D.K. Clawson, R.D. Dillard, S.E. Draheim, L.W. Hartley, N.D. Jones, E.D. Mihelich, J.L. Olkowski, D.W. Snyder, C. Sommers, J.-P. Wery

Nat Struct Biol. 1995; 2(6): 458–465. doi: 10.1038/nsb0695-458

PMCID:: PMC7097651

Abstract Article PDF–11M

Select item 683843512.

Context-dependent effect of sPLA₂-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer

Gopal L. Chovatiya, Raghava R. Sunkara, Sayoni Roy, Saloni R. Godbole, Sanjeev K. Waghmare

EBioMedicine. 2019 Oct; 48: 364–376. Published online 2019 Sep 11. doi: 10.1016/j.ebiom.2019.08.053

PMCID:: PMC6838435

Abstract Article PDF–6.8M

Select item 675355413.

Carotid artery color Doppler ultrasonography and plasma levels of lipoprotein-associated phospholipase A2 and cystatin C in arteriosclerotic cerebral infarction

Lei Huang, Shengguo Yao

J Int Med Res. 2019 Sep; 47(9): 4389–4396. Published online 2019 Jul 25. doi: 10.1177/0300060519859141

PMCID:: PMC6753554

Abstract Article PDF–341K

Select item 669120314.

Long non-coding RNA SLNCR1 regulates non-small cell lung cancer migration, invasion and stemness through interactions with secretory phospholipase A2

Wen Xu, Quan Xu, Dinghua Kuang, Zhongjun Wang, Qiuliang Lu, Qing Lin, Hao Wu, Liru Chen

Mol Med Rep. 2019 Sep; 20(3): 2591–2596. Published online 2019 Jul 23. doi: 10.3892/mmr.2019.10518

PMCID:: PMC6691203

Abstract Article PDF–636K

Select item 655762915.

Synergy between serum amyloid A and secretory phospholipase A₂

Shobini Jayaraman, Marcus Fändrich, Olga Gursky

eLife. 2019; 8: e46630. Published online 2019 May 21. doi: 10.7554/eLife.46630

PMCID:: PMC6557629

Abstract Article PDF–2.5M

Select item 605685216.

Group IIA-Secreted Phospholipase A₂ in Human Serum Kills Commensal but Not Clinical Enterococcus faecium Isolates

Fernanda L. Paganelli, Helen L. Leavis, Samantha He, Nina M. van Sorge, Christine Payré, Gérard Lambeau, Rob J. L. Willems, Suzan H. M. Rooijakkers

Infect Immun. 2018 Aug; 86(8): e00180-18. Prepublished online 2018 May 21. Published online 2018 Jul 23. doi: 10.1128/IAI.00180-18

PMCID:: PMC6056852

Abstract Article PDF–759K

Select item 603050917.

Activation of Notch-1 in oral epithelial cells by P. gingivalis triggers the expression of the antimicrobial protein PLA₂-IIA

Ahmad Al-Attar, Yelena Alimova, Sreenatha Kirakodu, Anastasia Kozal, Michael J. Novak, Arnold J. Stromberg, Luis Orraca, Janis Gonzalez-Martinez, Melween Martinez, Jeffrey L. Ebersole, Octavio A. Gonzalez

Mucosal Immunol. Author manuscript; available in PMC 2018 Sep 7.

Published in final edited form as: Mucosal Immunol. 2018 Jul; 11(4): 1047–1059. Published online 2018 Mar 7. doi: 10.1038/s41385-018-0014-7

Correction in:: Mucosal Immunol. 2019 Feb 22

PMCID:: PMC6030509

Abstract Article PDF–2.7M

Select item 594504818.

Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus

Susann Liebscher, Rebecca L. Ambrose, Turgut E. Aktepe, Andrea Mikulasova, Julia E. Prier, Leah K. Gillespie, Adam J. Lopez-Denman, Thusitha W. T. Rupasinghe, Dedreia Tull, Malcolm J. McConville, Jason M. Mackenzie

PLoS Pathog. 2018 Apr; 14(4): e1007029. Published online 2018 Apr 30. doi: 10.1371/journal.ppat.1007029

PMCID:: PMC5945048

Abstract Article PDF–11M

Select item 584607919.

Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity

Varnavas D. Mouchlis, Yuan Chen, J. Andrew McCammon, Edward A. Dennis

J Am Chem Soc. 2018 Mar 7; 140(9): 3285–3291. Published online 2018 Jan 17. doi: 10.1021/jacs.7b12045

PMCID:: PMC5846079

Abstract Article PDF–6.5M

Select item 558089620.

Secretory phospholipase A₂ group IIA modulates insulin sensitivity and metabolism

Michael S. Kuefner, Kevin Pham, Jeanna R. Redd, Erin J. Stephenson, Innocence Harvey, Xiong Deng, Dave Bridges, Eric Boilard, Marshall B. Elam, Edwards A. Park

J Lipid Res. 2017 Sep; 58(9): 1822–1833. Published online 2017 Jun 29. doi: 10.1194/jlr.M076141

PMCID:: PMC5580896

Abstract Article PDF–1.3M

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