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Select item 114236781.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 113624592.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 111168123.

Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution

Jason C. Casler, Clare S. Harper, Antoineen J. White, Heidi L. Anderson, Laura L. Lackner

J Cell Biol. 2024 Sep 2; 223(9): e202308144. Published online 2024 May 23. doi: 10.1083/jcb.202308144

PMCID:: PMC11116812

Abstract Article PDF–9.2M

Select item 111065284.

Inability to rescue stalled ribosomes results in overactivation of the integrated stress response

Ankanahalli N. Nanjaraj Urs, Victor Lasehinde, Lucas Kim, Elesa McDonald, Liewei L. Yan, Hani S. Zaher

J Biol Chem. 2024 May; 300(5): 107290. Published online 2024 Apr 16. doi: 10.1016/j.jbc.2024.107290

PMCID:: PMC11106528

Abstract Article PDF–1.6M

Select item 110888785.

Evidence that Xrn1 is in complex with Gcn1, and is required for full levels of eIF2α phosphorylation

Renuka Shanmugam, Reuben Anderson, Anja H. Schiemann, Evelyn Sattlegger

Biochem J. 2024 Apr 10; 481(7): 481–498. Published online 2024 Mar 28. doi: 10.1042/BCJ20220531

PMCID:: PMC11088878

Abstract Article PDF–3.2M

Select item 108724776.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687277.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988588.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001389.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 1023508610.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 970463611.

A genetic approach to identify amino acids in Gcn1 required for Gcn2 activation

Susanne Gottfried, Siaosi M. B. M. J. Koloamatangi, Clement Daube, Anja H. Schiemann, Evelyn Sattlegger

PLoS One. 2022; 17(11): e0277648. Published online 2022 Nov 28. doi: 10.1371/journal.pone.0277648

PMCID:: PMC9704636

Abstract Article PDF–3.4M

Select item 964897312.

Systematic analysis of membrane contact sites in Saccharomyces cerevisiae uncovers modulators of cellular lipid distribution

Inês Gomes Castro, Shawn P Shortill, Samantha Katarzyna Dziurdzik, Angela Cadou, Suriakarthiga Ganesan, Rosario Valenti, Yotam David, Michael Davey, Carsten Mattes, Ffion B Thomas, Reut Ester Avraham, Hadar Meyer, Amir Fadel, Emma J Fenech, Robert Ernst, Vanina Zaremberg, Tim P Levine, Christopher Stefan, Elizabeth Conibear, Maya Schuldiner

eLife. 2022; 11: e74602. Published online 2022 Nov 10. doi: 10.7554/eLife.74602

PMCID:: PMC9648973

Abstract Article PDF–8.0M

Select item 963802813.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 963098614.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 920981115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 884892616.

Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by integrated stress response regulators Gcn1 and Gcn20

Lisa Houston, Evan M. Platten, Sara M. Connelly, Jiyu Wang, Elizabeth J. Grayhack

RNA. 2022 Mar; 28(3): 320–339. doi: 10.1261/rna.078964.121

PMCID:: PMC8848926

Abstract Article PDF–8.4M

Select item 880492917.

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner

Md. Murad Khan, Seowon Lee, Sergio Couoh‐Cardel, Rebecca A Oot, Hyunmin Kim, Stephan Wilkens, Soung‐Hun Roh

EMBO J. 2022 Feb 1; 41(3): e109360. Published online 2021 Dec 17. doi: 10.15252/embj.2021109360

PMCID:: PMC8804929

Abstract Article PDF–5.5M

Select item 857691718.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L. Gupta, Jr.

J Cell Biol. 2021 Dec 6; 220(12): e202010155. Published online 2021 Nov 5. doi: 10.1083/jcb.202010155

PMCID:: PMC8576917

Abstract Article PDF–7.4M

Select item 809411719.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130