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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107742302.

Heterogeneity of endothelial VE-PTP downstream polarization, Tie2 activation, junctional claudin-5, and permeability in the aorta and vena cava

Peter Baluk, Keisuke Shirakura, Dietmar Vestweber, Donald M. McDonald

Cell Tissue Res. 2024; 395(1): 81–103. Published online 2023 Nov 30. doi: 10.1007/s00441-023-03844-9

PMCID:: PMC10774230

Abstract Article PDF–13M

Select item 106535283.

Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex

Anoek L. I. van Leeuwen, Elise Beijer, Roselique Ibelings, Nicole A. M. Dekker, Marjolein R. A. van der Steen, Joris J. T. H. Roelofs, Matijs van Meurs, Grietje Molema, Charissa E. van den Brom

PLoS One. 2023; 18(11): e0293673. Published online 2023 Nov 16. doi: 10.1371/journal.pone.0293673

PMCID:: PMC10653528

Abstract Article PDF–3.1M

Select item 103783254.

Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia

Peter J. Zwiers, Jacqueline P. F. E. Lucas, Rianne M. Jongman, Matijs van Meurs, Eliane R. Popa, Grietje Molema

Cells. 2023 Jul; 12(14): 1850. Published online 2023 Jul 14. doi: 10.3390/cells12141850

PMCID:: PMC10378325

Abstract Article PDF–6.2M

Select item 102788035.

Activation of Angiopoietin-Tie2 Signaling Protects the Kidney from Ischemic Injury by Modulation of Endothelial-Specific Pathways

Yanyang Li, Pan Liu, Yalu Zhou, Hiroshi Maekawa, John B. Silva, Mohammed Javeed Ansari, Khaled Boubes, Yazan Alia, Dilip K. Deb, Benjamin R. Thomson, Jing Jin, Susan E. Quaggin

J Am Soc Nephrol. 2023 Jun; 34(6): 969–987. Published online 2023 Feb 14. doi: 10.1681/ASN.0000000000000098

PMCID:: PMC10278803

Abstract Article

Select item 102127166.

Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain

Yuanyuan Wang, Libo Su, Wenwen Wang, Jinyue Zhao, Yanyan Wang, Sihan Li, Yan Liu, Renjie Chai, Xin Li, Zhaoqian Teng, Changmei Liu, Baoyang Hu, Fen Ji, Jianwei Jiao

Cell Prolif. 2023 May; 56(5): e13447. Published online 2023 Mar 13. doi: 10.1111/cpr.13447

PMCID:: PMC10212716

Abstract Article PDF–4.7M

Select item 100865907.

Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration

Keisuke Shirakura, Peter Baluk, Astrid F Nottebaum, Ute Ipe, Kevin G Peters, Donald M McDonald, Dietmar Vestweber

EMBO Mol Med. 2023 Apr; 15(4): e16128. Published online 2023 Feb 6. doi: 10.15252/emmm.202216128

PMCID:: PMC10086590

Abstract Article PDF–44M

Select item 97623458.

Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy

Moritz Jakab, Till Rostalski, Ki Hong Lee, Carolin Mogler, Hellmut G. Augustin

Cancer Res. 2022 Apr 1; 82(7): 1353–1364. Published online 2022 Apr 4. doi: 10.1158/0008-5472.CAN-21-3181

PMCID:: PMC9762345

Abstract Article PDF–1.4M

Select item 96136229.

Angiopoietin-1 is required for vortex vein and choriocapillaris development in mice

Pan Liu, Jeremy A. Lavine, Amani Fawzi, Susan E Quaggin, Benjamin R. Thomson

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2022 Nov; 42(11): 1413–1427. Published online 2022 Sep 29. doi: 10.1161/ATVBAHA.122.318151

PMCID:: PMC9613622

Abstract Article PDF–6.8M

Select item 942140010.

Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

Linh T. Trinh, Anna B. Osipovich, Leesa Sampson, Jonathan Wong, Chris V.E. Wright, Mark A. Magnuson

iScience. 2022 Sep 16; 25(9): 104905. Published online 2022 Aug 11. doi: 10.1016/j.isci.2022.104905

PMCID:: PMC9421400

Abstract Article PDF–4.7M

Select item 921865611.

Endothelial Cells Mediated by UCP2 Control the Neurogenic‐to‐Astrogenic Neural Stem Cells Fate Switch During Brain Development

Wenwen Wang, Libo Su, Yanyan Wang, Chenxiao Li, Fen Ji, Jianwei Jiao

Adv Sci (Weinh) 2022 Jun; 9(18): 2105208. Published online 2022 Apr 30. doi: 10.1002/advs.202105208

PMCID:: PMC9218656

Abstract Article PDF–8.7M

Select item 911080712.

The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner

Robert Luck, Andromachi Karakatsani, Bhavin Shah, Geza Schermann, Heike Adler, Janina Kupke, Nathalie Tisch, Hyun-Woo Jeong, Michaela Kerstin Back, Florian Hetsch, Anna D’Errico, Michele De Palma, Ellen Wiedtke, Dirk Grimm, Amparo Acker-Palmer, Jakob von Engelhardt, Ralf H. Adams, Hellmut G. Augustin, Carmen Ruiz de Almodóvar

Cell Rep. Author manuscript; available in PMC 2022 Aug 17.

Published in final edited form as: Cell Rep. 2021 Aug 17; 36(7): 109522. doi: 10.1016/j.celrep.2021.109522

PMCID:: PMC9110807

Abstract Article PDF–3.0M

Select item 899508713.

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac

Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson

Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131

PMCID:: PMC8995087

Abstract Article

Select item 891370614.

Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells

Yuki Mochida, Koji Ochiai, Takashi Nagase, Keiko Nonomura, Yoshihiro Akimoto, Hiroshi Fukuhara, Tatsuo Sakai, George Matsumura, Yoshihiro Yamaguchi, Miki Nagase

Sci Rep. 2022; 12: 4197. Published online 2022 Mar 10. doi: 10.1038/s41598-022-07987-7

PMCID:: PMC8913706

Abstract Article PDF–7.0M

Select item 886021615.

Single-Cell Transcriptome Analysis Reveals Embryonic Endothelial Heterogeneity at Spatiotemporal Level and Multifunctions of MicroRNA-126 in Mice

Fang-Hao Guo, Ya-Na Guan, Jun-Jun Guo, Lu-Jun Zhang, Jing-Jing Qiu, Yong Ji, Alex F. Chen, Qing Jing

Arterioscler Thromb Vasc Biol. 2022 Mar; 42(3): 326–342. Published online 2022 Jan 13. doi: 10.1161/ATVBAHA.121.317093

PMCID:: PMC8860216

Abstract Article PDF–5.2M

Select item 877675516.

Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction

Tianfei Fan, Yangfeng Hou, Weipeng Ge, Tianhui Fan, Xiaohang Feng, Wenjun Guo, Xiaomin Song, Ran Gao, Jing Wang

Commun Biol. 2022; 5: 81. Published online 2022 Jan 20. doi: 10.1038/s42003-022-03029-0

PMCID:: PMC8776755

Abstract Article PDF–6.2M

Select item 875164017.

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri, Miguel Constância

Dev Cell. 2022 Jan 10; 57(1): 63–79.e8. doi: 10.1016/j.devcel.2021.12.005

PMCID:: PMC8751640

Abstract Article

Select item 859004118.

The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy

Vanessa Tran, Andrea M. Weckman, Valerie M. Crowley, Lindsay S. Cahill, Kathleen Zhong, Ana Cabrera, Robyn E. Elphinstone, Victoria Pearce, Mwayiwawo Madanitsa, Linda Kalilani-Phiri, Victor Mwapasa, Carole Khairallah, Andrea L. Conroy, Feiko O. ter Kuile, John G. Sled, Kevin C. Kain

EBioMedicine. 2021 Nov; 73: 103683. Published online 2021 Nov 7. doi: 10.1016/j.ebiom.2021.103683

PMCID:: PMC8590041

Abstract Article PDF–1.5M

Select item 855634819.

Fli1 Promotes Vascular Morphogenesis by Regulating Endothelial Potential of Multipotent Myogenic Progenitors

Anwarul Ferdous, Sarvjeet Singh, Yuxuan Luo, Md. J. Abedin, Nan Jiang, Cameron E. Perry, Bret M. Evers, Thomas G. Gillette, Michael Kyba, Maria Trojanowska, Joseph A. Hill

Circ Res. Author manuscript; available in PMC 2022 Oct 29.

Published in final edited form as: Circ Res. 2021 Oct 29; 129(10): 949–964. Published online 2021 Sep 21. doi: 10.1161/CIRCRESAHA.121.318986

PMCID:: PMC8556348

Abstract Article PDF–1.9M

Select item 843105620.

Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy

Jennifer A. Courtney, Rebecca L. Wilson, James Cnota, Helen N. Jones

Int J Mol Sci. 2021 Sep; 22(17): 9532. Published online 2021 Sep 2. doi: 10.3390/ijms22179532

PMCID:: PMC8431056

Abstract Article PDF–9.2M

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