PMC Links for GEO Profiles (Select 118240667) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 92209484.

A reengineered common chain cytokine augments CD8⁺ T cell–dependent immunotherapy

Anirban Banerjee, Dongge Li, Yizhan Guo, Zhongcheng Mei, Christine Lau, Kelly Chen, John Westwick, Jeffery B. Klauda, Adam Schrum, Eric R. Lazear, Alexander S. Krupnick

JCI Insight. 2022 May 23; 7(10): e158889. Published online 2022 May 23. doi: 10.1172/jci.insight.158889

PMCID:: PMC9220948

Abstract Article PDF–3.2M

Select item 90439585.

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice

Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo

Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378

PMCID:: PMC9043958

Abstract Article PDF–8.1M

Select item 89173476.

Compartmentalized citrullination in Muller glial endfeet during retinal degeneration

Sarah I. Palko, Nicholas J. Saba, Elias Mullane, Benjamin D. Nicholas, Yosuke Nagasaka, Jayakrishna Ambati, Bradley D. Gelfand, Akihito Ishigami, Paola Bargagna-Mohan, Royce Mohan

Proc Natl Acad Sci U S A. 2022 Mar 1; 119(9): e2121875119. Published online 2022 Feb 23. doi: 10.1073/pnas.2121875119

PMCID:: PMC8917347

Abstract Article PDF–1.4M

Select item 88073957.

PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression

Shengnan Yuan, Xiaomin Wang, Shuaibing Hou, Tengxiao Guo, Yanjie Lan, Shuang Yang, Fei Zhao, Juan Gao, Yuxia Wang, Yajing Chu, Jun Shi, Tao Cheng, Weiping Yuan

Leukemia. 2022; 36(2): 370–382. Published online 2021 Aug 31. doi: 10.1038/s41375-021-01392-1

PMCID:: PMC8807395

Abstract Article PDF–3.3M

Select item 83479368.

A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis

Chun-Hao Hung, Tung-Liang Lee, Anna Yu-Szu Huang, Kang-Chung Yang, Yu-Chiau Shyu, Shau-Ching Wen, Mu-Jie Lu, Shinsheng Yuan, Che-Kun James Shen

Int J Mol Sci. 2021 Aug; 22(15): 8024. Published online 2021 Jul 27. doi: 10.3390/ijms22158024

PMCID:: PMC8347936

Abstract Article PDF–4.4M

Select item 81598849.

Janus Kinase 3 Deficiency Promotes Vascular Re-endothelialization

Yung-Chun Wang, Dunpeng Cai, Xiao-Bing Cui, Ya-Hui Chuang, William P. Fay, Shi-You Chen

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Jun; 41(6): 2019–2026. Published online 2021 Apr 29. doi: 10.1161/ATVBAHA.121.316293

PMCID:: PMC8159884

Abstract Article PDF–1.0M

Select item 811921810.

Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata

Zhenpeng Dai, James Chen, Yuqian Chang, Angela M. Christiano

JCI Insight. 2021 Apr 8; 6(7): e142205. Published online 2021 Apr 8. doi: 10.1172/jci.insight.142205

PMCID:: PMC8119218

Abstract Article PDF–2.1M

Select item 811561911.

Generation of a chemical genetic model for JAK3

Judit Remenyi, Rangeetha Jayaprakash Naik, Jinhua Wang, Momchil Razsolkov, Alyssa Verano, Quan Cai, Li Tan, Rachel Toth, Samantha Raggett, Carla Baillie, Ryan Traynor, C. James Hastie, Nathanael S. Gray, J. Simon C. Arthur

Sci Rep. 2021; 11: 10093. Published online 2021 May 12. doi: 10.1038/s41598-021-89356-4

PMCID:: PMC8115619

Abstract Article PDF–4.2M

Select item 799445012.

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

José Gabriel Barcia Durán, Tyler Lu, Sean Houghton, Fuqiang Geng, Ryan Schreiner, Jenny Xiang, Shahin Rafii, David Redmond, Raphaël Lis

Commun Biol. 2021; 4: 406. Published online 2021 Mar 25. doi: 10.1038/s42003-021-01846-3

PMCID:: PMC7994450

Abstract Article PDF–7.1M

Select item 787606713.

Supraphysiological Levels of IL-2 in Jak3-Deficient Mice Promote Strong Proliferative Responses of Adoptively Transferred Naive CD8⁺ T Cells

Gil-Woo Lee, Sung-Woo Lee, Juhee Kim, Young-Jun Ju, Hee-Ok Kim, Cheol-Heui Yun, Jae-Ho Cho

Front Immunol. 2020; 11: 616898. Published online 2021 Jan 28. doi: 10.3389/fimmu.2020.616898

PMCID:: PMC7876067

Abstract Article PDF–1.0M

Select item 737600914.

Insulin2^Q104del (Kuma) mutant mice develop diabetes with dominant inheritance

Daisuke Sakano, Airi Inoue, Takayuki Enomoto, Mai Imasaka, Seiji Okada, Mutsumi Yokota, Masato Koike, Kimi Araki, Shoen Kume

Sci Rep. 2020; 10: 12187. Published online 2020 Jul 22. doi: 10.1038/s41598-020-68987-z

PMCID:: PMC7376009

Abstract Article PDF–4.1M

Select item 688814315.

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Michael Broux, Cristina Prieto, Sofie Demeyer, Marlies Vanden Bempt, Llucia Alberti-Servera, Inge Lodewijckx, Roel Vandepoel, Nicole Mentens, Olga Gielen, Kris Jacobs, Ellen Geerdens, Carmen Vicente, Charles E. de Bock, Jan Cools

Blood. 2019 Oct 17; 134(16): 1323–1336. Prepublished online 2019 Sep 6. doi: 10.1182/blood.2019000015

PMCID:: PMC6888143

Abstract Article

Select item 645354216.

Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis

Chen-Hua Chuang, Peyton G Greenside, Zoë N Rogers, Jennifer J Brady, Dian Yang, Rosanna K Ma, Deborah R Caswell, Shin-Heng Chiou, Aidan F Winters, Barbara M Grüner, Gokul Ramaswami, Andrew L Spencley, Kimberly E Kopecky, Leanne C Sayles, E Alejandro Sweet-Cordero, Jin Billy Li, Anshul Kundaje, Monte M Winslow

Nat Med. Author manuscript; available in PMC 2019 Apr 8.

Published in final edited form as: Nat Med. 2017 Mar; 23(3): 291–300. Published online 2017 Feb 13. doi: 10.1038/nm.4285

PMCID:: PMC6453542

Abstract Article PDF–2.5M

Select item 620317317.

Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1^rd8 Allele

Bo Chang, Bernard FitzMaurice, Jieping Wang, Benjamin E. Low, Michael V. Wiles, Patsy M. Nishina

Invest Ophthalmol Vis Sci. 2018 Oct; 59(12): 5127–5139. doi: 10.1167/iovs.18-25046

PMCID:: PMC6203173

Abstract Article PDF–2.3M

Select item 603965818.

Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models

Paola Rivera-Munoz, Anouchka P. Laurent, Aurelie Siret, Cecile K. Lopez, Cathy Ignacimouttou, Melanie G. Cornejo, Olivia Bawa, Philippe Rameau, Olivier A. Bernard, Philippe Dessen, Gary D. Gilliland, Thomas Mercher, Sébastien Malinge

Blood Adv. 2018 Jul 10; 2(13): 1616–1627. Published online 2018 Jul 9. doi: 10.1182/bloodadvances.2018016089

PMCID:: PMC6039658

Abstract Article PDF–2.2M

Select item 582726619.

JAK signaling regulates germline cyst breakdown and primordial follicle formation in mice

Kun Huang, Ye Wang, Tuo Zhang, Meina He, Guanghong Sun, Jia Wen, Hao Yan, Han Cai, Changfu Yong, Guoliang Xia, Chao Wang

Biol Open. 2018 Jan 15; 7(1): bio029470. Published online 2017 Dec 14. doi: 10.1242/bio.029470

PMCID:: PMC5827266

Abstract Article PDF–6.5M

Select item 563310420.

Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin

Jayshree Mishra, Jugal Kishore Das, Narendra Kumar

J Biol Chem. 2017 Oct 6; 292(40): 16406–16419. Published online 2017 Aug 17. doi: 10.1074/jbc.M117.811802

PMCID:: PMC5633104

Abstract Article PDF–3.1M

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