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Select item 105757321.

Zfp335 establishes eTreg lineage and neonatal immune tolerance by targeting Hadha-mediated fatty acid oxidation

Xin Wang, Lina Sun, Biao Yang, Wenhua Li, Cangang Zhang, Xiaofeng Yang, Yae Sun, Xiaonan Shen, Yang Gao, Bomiao Ju, Yafeng Gao, Dan Liu, Jiapeng Song, Xiaoxuan Jia, Yanhong Su, Anjun Jiao, Haiyan Liu, Lianjun Zhang, Lan He, Lei Lei, WanJun Chen, Baojun Zhang

J Clin Invest. 2023 Oct 16; 133(20): e166628. Published online 2023 Oct 16. doi: 10.1172/JCI166628

PMCID:: PMC10575732

Abstract Article PDF–12M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 100407883.

ALDH2 attenuates myocardial pyroptosis through breaking down Mitochondrion-NLRP3 inflammasome pathway in septic shock

Ying Zhang, Ying Lv, Qingju Zhang, Xingfang Wang, Qi Han, Yan Liang, Simeng He, Qiuhuan Yuan, Jiaqi Zheng, Changchang Xu, Xiangxin Zhang, Zichen Wang, Huaxiang Yu, Li Xue, Jiali Wang, Feng Xu, Jiaojiao Pang, Yuguo Chen

Front Pharmacol. 2023; 14: 1125866. Published online 2023 Mar 13. doi: 10.3389/fphar.2023.1125866

PMCID:: PMC10040788

Abstract Article PDF–5.5M

Select item 98894374.

HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway

Jiexia Ding, Lili Wu, Guoxian Zhu, Jing Zhu, Pingping Luo, Youming Li

Mol Biol Rep. 2023; 50(2): 961–970. Published online 2022 Nov 14. doi: 10.1007/s11033-022-07965-2

PMCID:: PMC9889437

Abstract Article PDF–4.0M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92897096.

TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis

Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen

EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777

PMCID:: PMC9289709

Abstract Article PDF–2.3M

Select item 87704647.

The mitochondrial β-oxidation enzyme HADHA restrains hepatic glucagon response by promoting β-hydroxybutyrate production

An Pan, Xiao-Meng Sun, Feng-Qing Huang, Jin-Feng Liu, Yuan-Yuan Cai, Xin Wu, Raphael N. Alolga, Ping Li, Bao-Lin Liu, Qun Liu, Lian-Wen Qi

Nat Commun. 2022; 13: 386. Published online 2022 Jan 19. doi: 10.1038/s41467-022-28044-x

PMCID:: PMC8770464

Abstract Article PDF–4.5M

Select item 87442578.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 85138719.

The enzyme activity of mitochondrial trifunctional protein is not altered by lysine acetylation or lysine succinylation

Yuxun Zhang, Eric Goetzman

PLoS One. 2021; 16(10): e0256619. Published online 2021 Oct 13. doi: 10.1371/journal.pone.0256619

PMCID:: PMC8513871

Abstract Article PDF–1.1M

Select item 844633810.

ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1

Wesley Wang, Dolena Ledee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073

PMCID:: PMC8446338

Abstract Article PDF–830K

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 726957213.

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α

M. Ahsan Siraj, Dhanwantee Mundil, Sanja Beca, Abdul Momen, Eric A. Shikatani, Talat Afroze, Xuetao Sun, Ying Liu, Siavash Ghaffari, Warren Lee, Michael B. Wheeler, Gordon Keller, Peter Backx, Mansoor Husain

J Clin Invest. 2020 Mar 2; 130(3): 1392–1404. Published online 2020 Jan 27. doi: 10.1172/JCI99934

PMCID:: PMC7269572

Abstract Article PDF–1.4M

Select item 672539414.

Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes

Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo

J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005

PMCID:: PMC6725394

Abstract Article PDF–682K

Select item 629804015.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 624418316.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 619387217.

Rearrangement of the Protein Phosphatase 1 Interactome during Heart Failure Progression

David Y. Chiang, Katherina M. Alsina, Eleonora Corradini, Martin Fitzpatrick, Li Ni, Satadru K. Lahiri, Julia Reynolds, Xiaolu Pan, Larry Scott, Jr, Albert J.R. Heck, Xander H.T. Wehrens

Circulation. Author manuscript; available in PMC 2019 Oct 9.

Published in final edited form as: Circulation. 2018 Oct 9; 138(15): 1569–1581. doi: 10.1161/CIRCULATIONAHA.118.034361

PMCID:: PMC6193872

Abstract Article PDF–2.4M

Select item 606634018.

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation

Catherine A. Makarewich, Kedryn K. Baskin, Amir Z. Munir, Svetlana Bezprozvannaya, Gaurav Sharma, Chalermchai Khemtong, Akansha M. Shah, John R. McAnally, Craig R. Malloy, Luke I. Szweda, Rhonda Bassel-Duby, Eric N. Olson

Cell Rep. Author manuscript; available in PMC 2018 Jul 30.

Published in final edited form as: Cell Rep. 2018 Jun 26; 23(13): 3701–3709. doi: 10.1016/j.celrep.2018.05.058

PMCID:: PMC6066340

Abstract Article PDF–1.0M

Select item 598339219.

Regulation of mitochondrial trifunctional protein modulates nonalcoholic fatty liver disease in mice

Fatiha Nassir, Justin J. Arndt, Sarah A. Johnson, Jamal A. Ibdah

J Lipid Res. 2018 Jun; 59(6): 967–973. Published online 2018 Mar 26. doi: 10.1194/jlr.M080952

PMCID:: PMC5983392

Abstract Article PDF–991K

Select item 586277120.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

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