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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 91917312.

Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice

Seiya Oura, Toshiaki Hino, Takashi Satoh, Taichi Noda, Takayuki Koyano, Ayako Isotani, Makoto Matsuyama, Shizuo Akira, Kei-ichiro Ishiguro, Masahito Ikawa

PLoS Genet. 2022 Jun; 18(6): e1010241. Published online 2022 Jun 1. doi: 10.1371/journal.pgen.1010241

PMCID:: PMC9191731

Abstract Article PDF–4.1M

Select item 65441503.

Prdm9 and meiotic cohesin proteins cooperatively promote DNA double-strand break formation in mammalian spermatocytes

Tanmoy Bhattacharyya, Michael Walker, Natalie R Powers, Catherine Brunton, Alexander D Fine, Petko M Petkov, Mary Ann Handel

Curr Biol. Author manuscript; available in PMC 2020 Mar 18.

Published in final edited form as: Curr Biol. 2019 Mar 18; 29(6): 1002–1018.e7. Published online 2019 Mar 7. doi: 10.1016/j.cub.2019.02.007

Correction in:: Curr Biol. 2021 Mar 22; 31(6): 1351.

PMCID:: PMC6544150

Abstract Article PDF–2.6M

Select item 54816254.

Ectopic expression of meiotic cohesin RAD21L promotes adjacency of homologous chromosomes in somatic cells

Mei RONG, Sachi MIYAUCHI, Jibak LEE

J Reprod Dev. 2017 Jun; 63(3): 227–234. Published online 2017 Feb 26. doi: 10.1262/jrd.2016-171

PMCID:: PMC5481625

Abstract Article PDF–2.7M

Select item 54419615.

Sororin is enriched at the central region of synapsed meiotic chromosomes

Philip W. Jordan, Craig Eyster, Jingrong Chen, Roberto J. Pezza, Susannah Rankin

Chromosome Res. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Chromosome Res. 2017 Jun; 25(2): 115–128. Published online 2017 Jan 3. doi: 10.1007/s10577-016-9542-8

PMCID:: PMC5441961

Abstract Article PDF–2.1M

Select item 52958216.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 51779817.

Meiotic cohesin subunits RAD21L and REC8 are positioned at distinct regions between lateral elements and transverse filaments in the synaptonemal complex of mouse spermatocytes

Mei RONG, Atsushi MATSUDA, Yasushi HIRAOKA, Jibak LEE

J Reprod Dev. 2016 Dec; 62(6): 623–630. Published online 2016 Sep 26. doi: 10.1262/jrd.2016-127

PMCID:: PMC5177981

Abstract Article PDF–3.1M

Select item 50955918.

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

Laura Gómez-H, Natalia Felipe-Medina, Manuel Sánchez-Martín, Owen R. Davies, Isabel Ramos, Ignacio García-Tuñón, Dirk G. de Rooij, Ihsan Dereli, Attila Tóth, José Luis Barbero, Ricardo Benavente, Elena Llano, Alberto M. Pendas

Nat Commun. 2016; 7: 13298. Published online 2016 Oct 31. doi: 10.1038/ncomms13298

PMCID:: PMC5095591

Abstract Article PDF–4.9M

Select item 50850599.

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis

Uddipta Biswas, Kai Hempel, Elena Llano, Alberto Pendas, Rolf Jessberger

PLoS Genet. 2016 Oct; 12(10): e1006389. Published online 2016 Oct 28. doi: 10.1371/journal.pgen.1006389

PMCID:: PMC5085059

Abstract Article PDF–2.6M

Select item 488966710.

Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L

Ayobami Ward, Jessica Hopkins, Matthew Mckay, Steve Murray, Philip W. Jordan

G3 (Bethesda) 2016 Jun; 6(6): 1713–1724. Published online 2016 Apr 16. doi: 10.1534/g3.116.029462

PMCID:: PMC4889667

Abstract Article PDF–2.5M

Select item 473490711.

Functions of the MRE11 complex in the development and maintenance of oocytes

Akiko Inagaki, Ramon Roset, John H. J. Petrini

Chromosoma. 2016; 125: 151–162. Published online 2015 Aug 1. doi: 10.1007/s00412-015-0535-8

PMCID:: PMC4734907

Abstract Article PDF–2.8M

Select item 472990212.

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts

Emilie Abby, Sophie Tourpin, Jonathan Ribeiro, Katrin Daniel, Sébastien Messiaen, Delphine Moison, Justine Guerquin, Jean-Charles Gaillard, Jean Armengaud, Francina Langa, Attila Toth, Emmanuelle Martini, Gabriel Livera

Nat Commun. 2016; 7: 10324. Published online 2016 Jan 8. doi: 10.1038/ncomms10324

PMCID:: PMC4729902

Abstract Article PDF–4.0M

Select item 444673713.

MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse

Rajeev Kumar, Norbert Ghyselinck, Kei-ichiro Ishiguro, Yoshinori Watanabe, Anna Kouznetsova, Christer Höög, Edward Strong, John Schimenti, Katrin Daniel, Attila Toth, Bernard de Massy

J Cell Sci. 2015 May 1; 128(9): 1800–1811. doi: 10.1242/jcs.165464

PMCID:: PMC4446737

Abstract Article

Select item 419802714.

STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis

Tomoyuki Fukuda, Nanaho Fukuda, Ana Agostinho, Abrahan Hernández-Hernández, Anna Kouznetsova, Christer Höög

EMBO J. 2014 Jun 2; 33(11): 1243–1255. Published online 2014 May 5. doi: 10.1002/embj.201387329

PMCID:: PMC4198027

Abstract Article PDF–2.5M

Select item 396704815.

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes

Kei-ichiro Ishiguro, Jihye Kim, Hiroki Shibuya, Abrahan Hernández-Hernández, Aussie Suzuki, Tatsuo Fukagawa, Go Shioi, Hiroshi Kiyonari, Xin C. Li, John Schimenti, Christer Höög, Yoshinori Watanabe

Genes Dev. 2014 Mar 15; 28(6): 594–607. doi: 10.1101/gad.237313.113

PMCID:: PMC3967048

Abstract Article PDF–2.5M

Select item 396495516.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 357241017.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 338441818.

Meiotic cohesin complexes are essential for the formation of the axial element in mice

Elena Llano, Yurema Herrán, Ignacio García-Tuñón, Cristina Gutiérrez-Caballero, Enrique de Álava, José Luis Barbero, John Schimenti, Dirk G. de Rooij, Manuel Sánchez-Martín, Alberto M. Pendás

J Cell Biol. 2012 Jun 25; 197(7): 877–885. doi: 10.1083/jcb.201201100

PMCID:: PMC3384418

Abstract Article PDF–2.4M

Select item 334346319.

A unique role of cohesin-SA1 in gene regulation and development

Silvia Remeseiro, Ana Cuadrado, Gonzalo Gómez-López, David G Pisano, Ana Losada

EMBO J. 2012 May 2; 31(9): 2090–2102. Published online 2012 Mar 13. doi: 10.1038/emboj.2012.60

PMCID:: PMC3343463

Abstract Article PDF–2.9M

Select item 322952420.

Meiosis in Mice without a Synaptonemal Complex

Anna Kouznetsova, Ricardo Benavente, Albert Pastink, Christer Höög

PLoS One. 2011; 6(12): e28255. Published online 2011 Dec 2. doi: 10.1371/journal.pone.0028255

PMCID:: PMC3229524

Abstract Article PDF–3.4M

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