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Select item 111359941.

Regulation of insulin receptor function

J. F. Youngren

Cell Mol Life Sci. 2007 Apr; 64(7-8): 873. Published online 2007 Mar 8. doi: 10.1007/s00018-007-6359-9

PMCID:: PMC11135994

Abstract Article PDF–600K

Select item 65834042.

Intermittent Cyclic Mechanical Tension‐induced Down‐regulation of Ectonucleotide Pyrophosphatase Phosphodiesterase 1 Gene Expression is Mainly Dependent on TGF‐β1 in End‐plate Chondrocytes

Hong‐guang Xu, Zi‐rui Li, Hong Wang, Ping Liu, Sheng‐nan Xiang, Chuang‐dong Wang, Xiao‐ling Zhang

Orthop Surg. 2013 Feb; 5(1): 40–45. Published online 2013 Feb 18. doi: 10.1111/os.12028

PMCID:: PMC6583404

Abstract Article PDF–335K

Select item 62007933.

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Kazuki Kato, Hiroshi Nishimasu, Daisuke Oikawa, Seiichi Hirano, Hisato Hirano, Go Kasuya, Ryuichiro Ishitani, Fuminori Tokunaga, Osamu Nureki

Nat Commun. 2018; 9: 4424. Published online 2018 Oct 24. doi: 10.1038/s41467-018-06922-7

PMCID:: PMC6200793

Abstract Article PDF–1.3M

Select item 61769354.

Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling

Yunyun Jin, Qian Cong, Jelena Gvozdenovic-Jeremic, Jiajie Hu, Yiqun Zhang, Robert Terkeltaub, Yingzi Yang

Development. 2018 Sep 15; 145(18): dev164830. Published online 2018 Sep 20. doi: 10.1242/dev.164830

PMCID:: PMC6176935

Abstract Article

Select item 56998875.

Unilateral anterior crossbite induces aberrant mineral deposition in degenerative temporomandibular cartilage in rats

M. Zhang, H. Wang, J. Zhang, H. Zhang, H. Yang, X. Wan, L. Jing, L. Lu, X. Liu, S. Yu, W. Chang, M. Wang

Osteoarthritis Cartilage. Author manuscript; available in PMC 2017 Nov 22.

Published in final edited form as: Osteoarthritis Cartilage. 2016 May; 24(5): 921–931. Published online 2015 Dec 31. doi: 10.1016/j.joca.2015.12.009

PMCID:: PMC5699887

Abstract Article PDF–1.1M

Select item 45492036.

Acidosis Is a key regulator of osteoblast ecto‐nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity

Isabel R. Orriss, Michelle L. Key, Mark O.R. Hajjawi, José L. Millán, Timothy R. Arnett

J Cell Physiol. 2015 Dec; 230(12): 3049–3056. Published online 2015 Aug 24. doi: 10.1002/jcp.25041

PMCID:: PMC4549203

Abstract Article PDF–1.3M

Select item 42575367.

Spontaneous asj-2J Mutant Mouse as a Model for Generalized Arterial Calcification of Infancy: A Large Deletion/Insertion Mutation in the Enpp1 Gene

Qiaoli Li, C. Herbert Pratt, Louise A. Dionne, Heather Fairfield, Son Yong Karst, John P. Sundberg, Jouni Uitto

PLoS One. 2014; 9(12): e113542. Published online 2014 Dec 5. doi: 10.1371/journal.pone.0113542

PMCID:: PMC4257536

Abstract Article PDF–1.9M

Select item 42324688.

Hydrolysis of 2'3'-cGAMP by ENPP1 and design of non-hydrolyzable analogs

Lingyin Li, Qian Yin, Pia Kuss, Zoltan Maliga, José L. Millán, Hao Wu, Timothy J. Mitchison

Nat Chem Biol. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Nat Chem Biol. 2014 Dec; 10(12): 1043–1048. Published online 2014 Oct 26. doi: 10.1038/nchembio.1661

Correction in:: Nat Chem Biol. 2015 Mar; 11(3): 235.

Correction in:: Nat Chem Biol. 2015 Sep; 11(9): 741.

PMCID:: PMC4232468

Abstract Article PDF–2.4M

Select item 37593429.

Mutant Enpp1^asj mice as a model for generalized arterial calcification of infancy

Qiaoli Li, Haitao Guo, David W. Chou, Annerose Berndt, John P. Sundberg, Jouni Uitto

Dis Model Mech. 2013 Sep; 6(5): 1227–1235. Published online 2013 Jun 20. doi: 10.1242/dmm.012765

PMCID:: PMC3759342

Abstract Article

Select item 370250110.

Enpp1: A Potential Facilitator of Breast Cancer Bone Metastasis

Wen Min Lau, Michele Doucet, Ryan Stadel, David Huang, Kristy L. Weber, Scott L. Kominsky

PLoS One. 2013; 8(7): e66752. Published online 2013 Jul 5. doi: 10.1371/journal.pone.0066752

PMCID:: PMC3702501

Abstract Article PDF–2.2M

Select item 363083511.

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia

Jonathan M. Flanagan, Vivien Sheehan, Heidi Linder, Thad A. Howard, Yong-Dong Wang, Carolyn C. Hoppe, Banu Aygun, Robert J. Adams, Geoffrey A. Neale, Russell E. Ware

Blood. 2013 Apr 18; 121(16): 3237–3245. Prepublished online 2013 Feb 19. doi: 10.1182/blood-2012-10-464156

Correction in:: Blood. 2016 Jun 16; 127(24): 3104.

PMCID:: PMC3630835

Abstract Article

Select item 347949912.

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

Kazuki Kato, Hiroshi Nishimasu, Shinichi Okudaira, Emiko Mihara, Ryuichiro Ishitani, Junichi Takagi, Junken Aoki, Osamu Nureki

Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42): 16876–16881. Published online 2012 Oct 1. doi: 10.1073/pnas.1208017109

PMCID:: PMC3479499

Abstract Article PDF–2.1M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304681814.

The ENPP1 Q121 Variant Predicts Major Cardiovascular Events in High-Risk Individuals: Evidence for Interaction With Obesity in Diabetic Patients

Simonetta Bacci, Stefano Rizza, Sabrina Prudente, Belinda Spoto, Christine Powers, Antonio Facciorusso, Antonio Pacilli, Davide Lauro, Alessandra Testa, Yuan-Yuan Zhang, Giuseppe Di Stolfo, Francesca Mallamaci, Giovanni Tripepi, Rui Xu, Davide Mangiacotti, Filippo Aucella, Renato Lauro, Ernest V. Gervino, Thomas H. Hauser, Massimiliano Copetti, Salvatore De Cosmo, Fabio Pellegrini, Carmine Zoccali, Massimo Federici, Alessandro Doria, Vincenzo Trischitta

Diabetes. 2011 Mar; 60(3): 1000–1007. Published online 2011 Feb 21. doi: 10.2337/db10-1300

PMCID:: PMC3046818

Abstract Article PDF–815K

Select item 293580115.

UBXD4, a UBX-Containing Protein, Regulates the Cell Surface Number and Stability of α3-Containing Nicotinic Acetylcholine Receptors

Khosrow Rezvani, Yanfen Teng, Yaping Pan, John A. Dani, Jon Lindstrom, Eduardo A. García Gras, J. Michael McIntosh, Mariella De Biasi

J Neurosci. 2009 May 27; 29(21): 6883–6896. doi: 10.1523/JNEUROSCI.4723-08.2009

PMCID:: PMC2935801

Abstract Article PDF–1.2M

Select item 282018316.

Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene

Varda Levy-Litan, Eli Hershkovitz, Luba Avizov, Neta Leventhal, Dani Bercovich, Vered Chalifa-Caspi, Esther Manor, Sophia Buriakovsky, Yair Hadad, James Goding, Ruti Parvari

Am J Hum Genet. 2010 Feb 12; 86(2): 273–278. doi: 10.1016/j.ajhg.2010.01.010

PMCID:: PMC2820183

Abstract Article PDF–882K

Select item 282016617.

Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets

Bettina Lorenz-Depiereux, Dirk Schnabel, Dov Tiosano, Gabriele Häusler, Tim M. Strom

Am J Hum Genet. 2010 Feb 12; 86(2): 267–272. doi: 10.1016/j.ajhg.2010.01.006

PMCID:: PMC2820166

Abstract Article PDF–285K

Select item 279404518.

Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy

Frank Rutsch, Petra Böyer, Yvonne Nitschke, Nico Ruf, Bettina Lorenz-Depierieux, Tanja Wittkampf, Gabriele Weissen-Plenz, Rudolf-Josef Fischer, Zulf Mughal, John W. Gregory, Justin H. Davies, Chantal Loirat, Tim M. Strom, Dirk Schnabel, Peter Nürnberg, Robert Terkeltaub, GACI Study Group

Circ Cardiovasc Genet. Author manuscript; available in PMC 2009 Dec 15.

Published in final edited form as: Circ Cardiovasc Genet. 2008 Dec 1; 1(2): 133–140. doi: 10.1161/CIRCGENETICS.108.797704

PMCID:: PMC2794045

Abstract Article PDF–991K

Select item 200080419.

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

David Meyre, Nabila Bouatia-Naji, Agnès Tounian, Chantal Samson, Cécile Lecoeur, Vincent Vatin, Maya Ghoussaini, Christophe Wachter, Serge Hercberg, Guillaume Charpentier, Wolfgang Patsch, François Pattou, Marie-Aline Charles, Patrick Tounian, Karine Clément, Béatrice Jouret, Jacques Weill, Betty A. Maddux, Ira D. Goldfine, Andrew Walley, Philippe Boutin, Christian Dina, Philippe Froguel

Nat Genet. Author manuscript; available in PMC 2007 Oct 4.

Published in final edited form as: Nat Genet. 2005 Aug; 37(8): 863–867. Published online 2005 Jul 17. doi: 10.1038/ng1604

PMCID:: PMC2000804

Abstract Article PDF–694K

Select item 196451920.

Role of ENPP1 on Adipocyte Maturation

Jian Liang, Mingui Fu, Ester Ciociola, Manisha Chandalia, Nicola Abate

PLoS One. 2007; 2(9): e882. Published online 2007 Sep 12. doi: 10.1371/journal.pone.0000882

PMCID:: PMC1964519

Abstract Article PDF–364K

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