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Select item 104998211.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 102887922.

Functional defects in hiPSCs-derived cardiomyocytes from patients with a PLEKHM2-mutation associated with dilated cardiomyopathy and left ventricular non-compaction

Nataly Korover, Sharon Etzion, Alexander Cherniak, Tatiana Rabinski, Aviva Levitas, Yoram Etzion, Rivka Ofir, Ruti Parvari, Smadar Cohen

Biol Res. 2023; 56: 34. Published online 2023 Jun 23. doi: 10.1186/s40659-023-00442-5

PMCID:: PMC10288792

Abstract Article PDF–2.8M

Select item 98869033.

BORC complex specific components and Kinesin-1 mediate autophagy evasion by the autophagy-resistant Mycobacterium tuberculosis Beijing strain

Janpen Tunganuntarat, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Salisa Benjaskulluecha, Benjawan Wongprom, Tanapat Palaga, Tegar Adriansyah Putra Siregar, Suparerk Borwornpinyo, Angkana Chaiprasert, Prasit Palittapongarnpim, Marisa Ponpuak

Sci Rep. 2023; 13: 1663. Published online 2023 Jan 30. doi: 10.1038/s41598-023-28983-5

PMCID:: PMC9886903

Abstract Article PDF–24M

Select item 95973524.

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes

Shalini Rawat, Dhruba Chatterjee, Rituraj Marwaha, Gitanjali Charak, Gaurav Kumar, Shrestha Shaw, Divya Khatter, Sheetal Sharma, Cecilia de Heus, Nalan Liv, Judith Klumperman, Amit Tuli, Mahak Sharma

J Cell Biol. 2023 Jan 2; 222(1): e202108001. Published online 2022 Oct 25. doi: 10.1083/jcb.202108001

PMCID:: PMC9597352

Abstract Article PDF–12M

Select item 94339385.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 92626146.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 90375547.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 85529078.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 67781379.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 648562610.

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

Kieran McGourty, Teresa L. Thurston, Sophie A. Matthews, Laurie Pinaud, Luís Jaime Mota, David W. Holden

Science. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Science. 2012 Nov 16; 338(6109): 963–967. doi: 10.1126/science.1227037

PMCID:: PMC6485626

Abstract Article PDF–1.6M

Select item 537994311.

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

Rituraj Marwaha, Subhash B. Arya, Divya Jagga, Harmeet Kaur, Amit Tuli, Mahak Sharma

J Cell Biol. 2017 Apr 3; 216(4): 1051–1070. doi: 10.1083/jcb.201607085

PMCID:: PMC5379943

Abstract Article PDF–4.4M

Select item 478810512.

BORC, a Multisubunit Complex that Regulates Lysosome Positioning

Jing Pu, Christina Schindler, Rui Jia, Michal Jarnik, Peter Backlund, Juan S. Bonifacino

Dev Cell. Author manuscript; available in PMC 2016 Apr 20.

Published in final edited form as: Dev Cell. 2015 Apr 20; 33(2): 176–188. doi: 10.1016/j.devcel.2015.02.011

PMCID:: PMC4788105

Abstract Article PDF–3.2M

Select item 466416513.

PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction

Emad Muhammad, Aviva Levitas, Sonia R. Singh, Alex Braiman, Rivka Ofir, Sharon Etzion, Val C. Sheffield, Yoram Etzion, Lucie Carrier, Ruti Parvari

Hum Mol Genet. 2015 Dec 20; 24(25): 7227–7240. Published online 2015 Oct 12. doi: 10.1093/hmg/ddv423

PMCID:: PMC4664165

Abstract Article PDF–867K

Select item 384299814.

Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity

Amit Tuli, Jerome Thiery, Ashley M. James, Xavier Michelet, Mahak Sharma, Salil Garg, Keri B. Sanborn, Jordan S. Orange, Judy Lieberman, Michael B. Brenner

Mol Biol Cell. 2013 Dec 1; 24(23): 3721–3735. doi: 10.1091/mbc.E13-05-0259

PMCID:: PMC3842998

Abstract Article PDF–11M

Select item 369344215.

Structural Basis For Kinesin-1:Cargo Recognition

Stefano Pernigo, Anneri Lamprecht, Roberto A. Steiner, Mark P. Dodding

Science. Author manuscript; available in PMC 2013 Oct 19.

Published in final edited form as: Science. 2013 Apr 19; 340(6130): 356–359. Published online 2013 Mar 21. doi: 10.1126/science.1234264

PMCID:: PMC3693442

Abstract Article PDF–2.5M

Select item 324074416.

Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1

Cláudia Rosa-Ferreira, Sean Munro

Dev Cell. 2011 Dec 13; 21(6): 1171–1178. doi: 10.1016/j.devcel.2011.10.007

PMCID:: PMC3240744

Abstract Article

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 278515718.

Interaction between the SifA Virulence Factor and Its Host Target SKIP Is Essential for Salmonella Pathogenesis

Lautaro Diacovich, Audrey Dumont, Daniel Lafitte, Elodie Soprano, Aude-Agnès Guilhon, Christophe Bignon, Jean-Pierre Gorvel, Yves Bourne, Stéphane Méresse

J Biol Chem. 2009 Nov 27; 284(48): 33151–33160. Published online 2009 Sep 28. doi: 10.1074/jbc.M109.034975