PMC Links for GEO Profiles (Select 119003181) - PMC

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Items: 16

Select item 87942281.

MCU overexpression evokes disparate dose-dependent effects on mito-ROS and spontaneous Ca²⁺ release in hypertrophic rat cardiomyocytes

Shanna Hamilton, Radmila Terentyeva, Fruzsina Perger, Benjamín Hernández Orengo, Benjamin Martin, Matthew W. Gorr, Andriy E. Belevych, Richard T. Clements, Sandor Györke, Dmitry Terentyev

Am J Physiol Heart Circ Physiol. 2021 Oct 1; 321(4): H615–H632. Published online 2021 Aug 20. doi: 10.1152/ajpheart.00126.2021

PMCID:: PMC8794228

Abstract Article

Select item 63361962.

Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters

Rozbeh Baradaran, Chongyuan Wang, Andrew Francis Siliciano, Stephen Barstow Long

Nature. Author manuscript; available in PMC 2019 Jul 11.

Published in final edited form as: Nature. 2018 Jul; 559(7715): 580–584. Published online 2018 Jul 11. doi: 10.1038/s41586-018-0331-8

PMCID:: PMC6336196

Abstract Article PDF–3.8M

Select item 50877493.

Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle

Sergio De La Fuente, Celia Fernandez-Sanz, Caitlin Vail, Elorm J. Agra, Kira Holmstrom, Junhui Sun, Jyotsna Mishra, Dewight Williams, Toren Finkel, Elizabeth Murphy, Suresh K. Joseph, Shey-Shing Sheu, György Csordás

J Biol Chem. 2016 Oct 28; 291(44): 23343–23362. Published online 2016 Sep 16. doi: 10.1074/jbc.M116.755496

PMCID:: PMC5087749

Abstract Article PDF–5.5M

Select item 48928894.

Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex

Ming-Feng Tsai, Charles B Phillips, Matthew Ranaghan, Chen-Wei Tsai, Yujiao Wu, Carole Williams, Christopher Miller

eLife. 2016; 5: e15545. Published online 2016 Apr 21. doi: 10.7554/eLife.15545

Correction in:: eLife. 2017; 6: e26228.

PMCID:: PMC4892889

Abstract Article PDF–2.5M

Select item 42410885.

Cardiac responses to β-adrenoceptor stimulation is partly dependent on mitochondrial calcium uniporter activity

E Fernández-Sada, C Silva-Platas, C A Villegas, S L Rivero, B C Willis, N García, J R Garza, Y Oropeza-Almazán, C A Valverde, G Mazzocchi, C Zazueta, G Torre-Amione, G García-Rivas

Br J Pharmacol. 2014 Sep; 171(18): 4207–4221. Published online 2014 Jul 1. doi: 10.1111/bph.12684

PMCID:: PMC4241088

Abstract Article PDF–1.3M

Select item 41418776.

A 40 kDa protein of the inner membrane is the mitochondrial calcium uniporter

Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto

Nature. Author manuscript; available in PMC 2014 Aug 22.

Published in final edited form as: Nature. 2011 Aug 18; 476(7360): 336–340. Published online 2011 Jun 19. doi: 10.1038/nature10230

PMCID:: PMC4141877

Abstract Article PDF–1.3M

Select item 40916297.

EMRE is an essential component of the mitochondrial calcium uniporter complex

Yasemin Sancak, Andrew L. Markhard, Toshi Kitami, Erika Kovács-Bogdán, Kimberli J. Kamer, Namrata D. Udeshi, Steven A. Carr, Dipayan Chaudhuri, David E. Clapham, Andrew A. Li, Sarah E. Calvo, Olga Goldberger, Vamsi K. Mootha

Science. Author manuscript; available in PMC 2014 Jul 10.

Published in final edited form as: Science. 2013 Dec 13; 342(6164): 1379–1382. Published online 2013 Nov 14. doi: 10.1126/science.1242993

PMCID:: PMC4091629

Abstract Article PDF–711K

Select item 39888918.

MICU1 and MICU2 Finely Tune the Mitochondrial Ca²⁺ Uniporter by Exerting Opposite Effects on MCU Activity

Maria Patron, Vanessa Checchetto, Anna Raffaello, Enrico Teardo, Denis Vecellio Reane, Maura Mantoan, Veronica Granatiero, Ildikò Szabò, Diego De Stefani, Rosario Rizzuto

Mol Cell. 2014 Mar 6; 53(5): 726–737. doi: 10.1016/j.molcel.2014.01.013

PMCID:: PMC3988891

Abstract Article

Select item 37713449.

The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit

Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto

EMBO J. 2013 Aug 28; 32(17): 2362–2376. Published online 2013 Jul 30. doi: 10.1038/emboj.2013.157

PMCID:: PMC3771344

Abstract Article PDF–2.3M

Select item 367331810.

MCU encodes the pore conducting mitochondrial calcium currents

Dipayan Chaudhuri, Yasemin Sancak, Vamsi K Mootha, David E Clapham

eLife. 2013; 2: e00704. Published online 2013 Jun 4. doi: 10.7554/eLife.00704

PMCID:: PMC3673318

Abstract Article PDF–1.5M

Select item 356711211.

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

Molly Plovanich, Roman L. Bogorad, Yasemin Sancak, Kimberli J. Kamer, Laura Strittmatter, Andrew A. Li, Hany S. Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner, Nathan Taneja, Jonathan OShea, Victor Koteliansky, Vamsi K. Mootha

PLoS One. 2013; 8(2): e55785. Published online 2013 Feb 7. doi: 10.1371/journal.pone.0055785

PMCID:: PMC3567112

Abstract Article PDF–1.0M

Select item 348672612.

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis, Molly Plovanich, Casey A. Belcher-Timme, Yasemin Sancak, X. Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L. Bogorad, Victor Koteliansky, Vamsi K. Mootha

Nature. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Nature. 2011 Jun 19; 476(7360): 341–345. Published online 2011 Jun 19. doi: 10.1038/nature10234

PMCID:: PMC3486726

Abstract Article PDF–2.5M

Select item 346731413.

Inactivation of Pde8b enhances memory, motor performance, and protects against age-induced motor coordination decay

Li-Chun Lisa Tsai, Guy Chiu-Kai Chan, Shannon N. Nangle, Masami Shimizu-Albergine, Graham Jones, Daniel R. Storm, Joseph A. Beavo, Larry S. Zweifel

Genes Brain Behav. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Genes Brain Behav. 2012 Oct; 11(7): 837–847. Published online 2012 Sep 4. doi: 10.1111/j.1601-183X.2012.00836.x

PMCID:: PMC3467314

Abstract Article PDF–1.5M

Select item 340063314.

The Mitochondrial Ca²⁺ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells

Andrei I. Tarasov, Francesca Semplici, Magalie A. Ravier, Elisa A. Bellomo, Timothy J. Pullen, Patrick Gilon, Israel Sekler, Rosario Rizzuto, Guy A. Rutter

PLoS One. 2012; 7(7): e39722. Published online 2012 Jul 19. doi: 10.1371/journal.pone.0039722

PMCID:: PMC3400633

Abstract Article PDF–736K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 277884416.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016