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Select item 91722921.

Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation

Chan Choo Yap, Laura Digilio, Lloyd P. McMahon, Tuanlao Wang, Bettina Winckler

J Neurosci. 2022 Jun 1; 42(22): 4415–4434. doi: 10.1523/JNEUROSCI.2530-21.2022

PMCID:: PMC9172292

Abstract Article PDF–8.9M

Select item 67258842.

The Small GTPase Rab7 Controls the Endosomal Trafficking and Neuritogenic Signaling of the Nerve Growth Factor Receptor TrkA

Smita Saxena, Cecilia Bucci, Joachim Weis, Alex Kruttgen

J Neurosci. 2005 Nov 23; 25(47): 10930–10940. doi: 10.1523/JNEUROSCI.2029-05.2005

PMCID:: PMC6725884

Abstract Article PDF–647K

Select item 67054973.

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway

Pingping Song, Katarina Trajkovic, Taiji Tsunemi, Dimitri Krainc

J Neurosci. 2016 Feb 24; 36(8): 2425–2437. doi: 10.1523/JNEUROSCI.2569-15.2016

PMCID:: PMC6705497

Abstract Article PDF–5.3M

Select item 66715324.

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

Maria Rita Spinosa, Cinzia Progida, Azzurra De Luca, Anna Maria Rosaria Colucci, Pietro Alifano, Cecilia Bucci

J Neurosci. 2008 Feb 13; 28(7): 1640–1648. doi: 10.1523/JNEUROSCI.3677-07.2008

PMCID:: PMC6671532

Abstract Article PDF–638K

Select item 66347195.

Quantitative Analysis of Synaptic Vesicle Rabs Uncovers Distinct Yet Overlapping Roles for Rab3a and Rab27b in Ca²⁺-Triggered Exocytosis

Nathan J. Pavlos, Mads Grønborg, Dietmar Riedel, John J. E. Chua, Janina Boyken, Tobias H. Kloepper, Henning Urlaub, Silvio O. Rizzoli, Reinhard Jahn

J Neurosci. 2010 Oct 6; 30(40): 13441–13453. doi: 10.1523/JNEUROSCI.0907-10.2010

PMCID:: PMC6634719

Abstract Article PDF–3.9M

Select item 65414396.

Critical role for Piccolo in synaptic vesicle retrieval

Frauke Ackermann, Kay Oliver Schink, Christine Bruns, Zsuzsanna Izsvák, F Kent Hamra, Christian Rosenmund, Craig Curtis Garner

eLife. 2019; 8: e46629. Published online 2019 May 10. doi: 10.7554/eLife.46629

PMCID:: PMC6541439

Abstract Article PDF–7.1M

Select item 60684647.

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

Sven Truckenbrodt, Abhiyan Viplav, Sebastian Jähne, Angela Vogts, Annette Denker, Hanna Wildhagen, Eugenio F Fornasiero, Silvio O Rizzoli

EMBO J. 2018 Aug 1; 37(15): e98044. Published online 2018 Jun 27. doi: 10.15252/embj.201798044

PMCID:: PMC6068464

Abstract Article PDF–2.6M

Select item 59281618.

Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment

Naomi Matsumoto, Mizuki Sekiya, Koujiro Tohyama, Eri Ishiyama-Matsuura, Ge-Hong Sun-Wada, Yoh Wada, Masamitsu Futai, Mayumi Nakanishi-Matsui

Sci Rep. 2018; 8: 6701. Published online 2018 Apr 30. doi: 10.1038/s41598-018-24918-7

PMCID:: PMC5928161

Abstract Article PDF–8.2M

Select item 58249589.

Identification and characterization of the BRI2 interactome in the brain

Filipa Martins, Ana M. Marafona, Cátia D. Pereira, Thorsten Müller, Christina Loosse, Katharina Kolbe, Odete A. B. da Cruz e Silva, Sandra Rebelo

Sci Rep. 2018; 8: 3548. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21453-3

PMCID:: PMC5824958

Abstract Article PDF–1.7M

Select item 555087410.

Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats

Lixuan Zhan, Siyuan Chen, Kongping Li, Donghai Liang, Xinyong Zhu, Liu Liu, Zhiwei Lu, Weiwen Sun, En Xu

Cell Death Dis. 2017 Jul; 8(7): e2949. Published online 2017 Jul 20. doi: 10.1038/cddis.2017.330

PMCID:: PMC5550874

Abstract Article PDF–9.0M

Select item 508277611.

Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A

Belén Fernández, Elena Fdez, Patricia Gómez-Suaga, Fernando Gil, Isabel Molina-Villalba, Isidro Ferrer, Sandip Patel, Grant C. Churchill, Sabine Hilfiker

Autophagy. 2016; 12(9): 1487–1506. Published online 2016 Jul 6. doi: 10.1080/15548627.2016.1190072

PMCID:: PMC5082776

Abstract Article PDF–2.0M

Select item 508254912.

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour

Benjamin J. Tyrrell, Emma F. Woodham, Heather J. Spence, Douglas Strathdee, Robert H. Insall, Laura M. Machesky

Pigment Cell Melanoma Res. 2016 Sep; 29(5): 559–571. Published online 2016 Sep 12. doi: 10.1111/pcmr.12506

PMCID:: PMC5082549

Abstract Article PDF–2.6M

Select item 500007613.

Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation

Jordan Follett, Andrea Bugarcic, Zhe Yang, Nicholas Ariotti, Suzanne J. Norwood, Brett M. Collins, Robert G. Parton, Rohan D. Teasdale

J Biol Chem. 2016 Aug 26; 291(35): 18283–18298. Published online 2016 Jul 6. doi: 10.1074/jbc.M115.703157

PMCID:: PMC5000076

Abstract Article PDF–5.8M

Select item 471421014.

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

Jorge Urresti, Marisol Ruiz-Meana, Elena Coccia, Juan Carlos Arévalo, José Castellano, Celia Fernández-Sanz, Koen M. O. Galenkamp, Laura Planells-Ferrer, Rana S. Moubarak, Núria Llecha-Cano, Stéphanie Reix, David García-Dorado, Bruna Barneda-Zahonero, Joan X. Comella

J Biol Chem. 2016 Jan 15; 291(3): 1221–1234. Published online 2015 Nov 18. doi: 10.1074/jbc.M115.677682

PMCID:: PMC4714210

Abstract Article PDF–2.9M

Select item 432864715.

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, Takashi Saito, Nobuhisa Iwata, Takaomi C Saido, Miyako Nakano, Yoshiki Yamaguchi, Yasuhiro Hashimoto, Matthias Staufenbiel, Hiroyuki Hatsuta, Shigeo Murayama, Hiroshi Manya, Tamao Endo, Naoyuki Taniguchi

EMBO Mol Med. 2015 Feb; 7(2): 175–189. Published online 2015 Jan 15. doi: 10.15252/emmm.201404438

PMCID:: PMC4328647

Abstract Article PDF–2.3M

Select item 399622616.

In Vivo Regulation of NGF-Mediated Functions by Nedd4-2 Ubiquitination of TrkA

Tao Yu, Laura Calvo, Begoña Anta, Saray López-Benito, Roger López-Bellido, Cristina Vicente-García, Lino Tessarollo, Raquel E. Rodriguez, Juan C. Arévalo

J Neurosci. 2014 Apr 23; 34(17): 6098–6106. doi: 10.1523/JNEUROSCI.4271-13.2014

PMCID:: PMC3996226

Abstract Article PDF–1.9M

Select item 397633517.

The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function

Y. Qin, Y. Deng, C.J. Ricketts, S. Srikantan, E. Wang, E.R. Maher, P. L.M. Dahia

Hum Mol Genet. 2014 May 1; 23(9): 2428–2439. Published online 2013 Dec 13. doi: 10.1093/hmg/ddt638

PMCID:: PMC3976335

Abstract Article PDF–1.3M

Select item 395374718.

Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

Sungyoon Moon, Dohyun Han, Yikwon Kim, Jonghwa Jin, Won-Kyung Ho, Youngsoo Kim

Sci Rep. 2014; 4: 4376. Published online 2014 Mar 14. doi: 10.1038/srep04376

PMCID:: PMC3953747

Abstract Article PDF–1.4M

Select item 389081019.

A mechanism for retromer endosomal coat complex assembly with cargo

Megan S. Harrison, Chia-Sui Hung, Ting-ting Liu, Romain Christiano, Tobias C. Walther, Christopher G. Burd

Proc Natl Acad Sci U S A. 2014 Jan 7; 111(1): 267–272. Published online 2013 Dec 16. doi: 10.1073/pnas.1316482111

PMCID:: PMC3890810

Abstract Article PDF–1.0M

Select item 383095520.

Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development

Qing Ouyang, Sofia B. Lizarraga, Michael Schmidt, Unikora Yang, Jingyi Gong, Debra Ellisor, Julie A. Kauer, Eric M. Morrow

Neuron. Author manuscript; available in PMC 2014 Oct 2.

Published in final edited form as: Neuron. 2013 Oct 2; 80(1): 10.1016/j.neuron.2013.07.043. Published online 2013 Sep 12. doi: 10.1016/j.neuron.2013.07.043