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Select item 112953481.

Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma

Alessandro Giammona, Chiara De Vellis, Enrica Crivaro, Luisa Maresca, Roberta Amoriello, Federica Ricci, Giulia Anichini, Silvia Pietrobono, David R. Pease, Martin E. Fernandez-Zapico, Clara Ballerini, Barbara Stecca

J Exp Clin Cancer Res. 2024; 43: 214. Published online 2024 Aug 2. doi: 10.1186/s13046-024-03138-0

PMCID:: PMC11295348

Abstract Article PDF–9.5M

Select item 112767172.

The Combined Immunohistochemical Expression of GLI1 and BCOR in Synovial Sarcomas for the Identification of Three Risk Groups and Their Prognostic Outcomes: A Study of 52 Patients

Francisco Giner, Emilio Medina-Ceballos, Raquel López-Reig, Isidro Machado, José Antonio López-Guerrero, Samuel Navarro, Luis Alberto Rubio-Martínez, Mónica Espino, Empar Mayordomo-Aranda, Antonio Llombart-Bosch

Int J Mol Sci. 2024 Jul; 25(14): 7615. Published online 2024 Jul 11. doi: 10.3390/ijms25147615

PMCID:: PMC11276717

Abstract Article PDF–4.1M

Select item 111936513.

GLI1 Co-Amplification in Well-differentiated/Dedifferentiated Liposarcomas: Clinicopathologic and Molecular Analysis of 92 Cases

Aarti E Sharma, Mark Dickson, Samuel Singer, Meera R. Hameed, Narasimhan P Agaram

Mod Pathol. Author manuscript; available in PMC 2024 Jun 23.

Published in final edited form as: Mod Pathol. 2024 Jun; 37(6): 100494. Published online 2024 Apr 15. doi: 10.1016/j.modpat.2024.100494

PMCID:: PMC11193651

Abstract Article PDF–2.9M

Select item 111592304.

Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase‐9 activation

Shuntaro Nagai, Masafumi Nakamura, Kosuke Yanai, Junji Wada, Takashi Akiyoshi, Hiroshi Nakashima, Kenoki Ohuchida, Norihiro Sato, Masao Tanaka, Mitsuo Katano

Cancer Sci. 2008 Jul; 99(7): 1377–1384. Published online 2008 Apr 11. doi: 10.1111/j.1349-7006.2008.00822.x

PMCID:: PMC11159230

Abstract Article PDF–467K

Select item 108371405.

Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma

Ling-Hui Zeng, Chao Tang, Minli Yao, Qiangqiang He, Meiyu Qv, Qianlei Ren, Yana Xu, Tingyu Shen, Weizhong Gu, Chengyun Xu, Chaochun Zou, Xing Ji, Ximei Wu, Jirong Wang

Nat Commun. 2024; 15: 987. Published online 2024 Feb 2. doi: 10.1038/s41467-024-45315-x

PMCID:: PMC10837140

Abstract Article PDF–3.0M

Select item 106798796.

FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway: FUNDC2 mediates TNBC progression via the AKT/GSK3β/GLI1 pathway

Liyang Yin, Renxian Cao, Zhuoqing Liu, Gang Luo, Yu Li, Xiaolong Zhou, Xiguang Chen, Ying Wu, Jun He, Xuyu Zu, Yingying Shen

Acta Biochim Biophys Sin (Shanghai) 2023 Nov 25; 55(11): 1770–1783. Published online 2023 Sep 11. doi: 10.3724/abbs.2023142

PMCID:: PMC10679879

Abstract Article PDF–4.0M

Select item 101735637.

MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer

Taiji Hamada, Michiyo Higashi, Seiya Yokoyama, Toshiaki Akahane, Masanori Hisaoka, Hirotsugu Noguchi, Tatsuhiko Furukawa, Akihide Tanimoto

BMC Cancer. 2023; 23: 424. Published online 2023 May 10. doi: 10.1186/s12885-023-10867-6

PMCID:: PMC10173563

Abstract Article PDF–2.1M

Select item 101580268.

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease

Yuming Huang, Chen Jiang, Liang Chen, Juanjuan Han, Ming Liu, Tingwen Zhou, Nianguo Dong, Kang Xu

Int J Biol Sci. 2023; 19(7): 2053–2066. Published online 2023 Apr 9. doi: 10.7150/ijbs.74123

PMCID:: PMC10158026

Abstract Article PDF–3.8M

Select item 101375759.

Identification of GLI1 and KIAA0825 Variants in Two Families with Postaxial Polydactyly

Safeer Ahmad, Muhammad Zeeshan Ali, Muhammad Muzammal, Amjad Ullah Khan, Muhammad Ikram, Mari Muurinen, Shabir Hussain, Petra Loid, Muzammil Ahmad Khan, Outi Mäkitie

Genes (Basel) 2023 Apr; 14(4): 869. Published online 2023 Apr 5. doi: 10.3390/genes14040869

PMCID:: PMC10137575

Abstract Article PDF–4.2M

Select item 964728710.

Expression of Shh, Gli1, and Cyr61 in Gastric Cancer Predicts Overall Survival of Patients: A Retrospective Study

Xiaoling Quan, Zhenming Zhang, Yujie Qin, Xin Gai, Qiling Tian, Yaqiong Guo, Jun Qian, Jiaxi Yao

Cancer Control. 2022 Jan-Dec; 29: 10732748221134398. Published online 2022 Nov 8. doi: 10.1177/10732748221134398

PMCID:: PMC9647287

Abstract Article PDF–1.3M

Select item 927967611.

ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1

A Jane Bardwell, Beibei Wu, Kavita Y Sarin, Marian L Waterman, Scott X Atwood, Lee Bardwell

Life Sci Alliance. 2022 Nov; 5(11): e202101353. Published online 2022 Jul 13. doi: 10.26508/lsa.202101353

PMCID:: PMC9279676

Abstract Article PDF–2.4M

Select item 926261412.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 920439013.

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles in stromal cells

Aranzazu Villasante, Amandine Godier-Furnemont, Alberto Hernandez-Barranco, Johanne Le Coq, Jasminka Boskovic, Hector Peinado, Jaume Mora, Josep Samitier, Gordana Vunjak-Novakovic

Transl Res. Author manuscript; available in PMC 2022 Jun 17.

Published in final edited form as: Transl Res. 2021 Nov; 237: 82–97. Published online 2021 Jul 2. doi: 10.1016/j.trsl.2021.06.006

PMCID:: PMC9204390

Abstract Article PDF–2.4M

Select item 912294614.

GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes

Taghi Manshouri, Ivo Veletic, Ping Li, C. Cameron Yin, Sean M. Post, Srdan Verstovsek, Zeev Estrov

Cell Death Dis. 2022 May; 13(5): 481. Published online 2022 May 20. doi: 10.1038/s41419-022-04932-4

PMCID:: PMC9122946

Abstract Article PDF–7.2M

Select item 903066815.

Two Cases of Temporomandibular Synovial Chondromatosis Associated with Gli1 Gene Mutation

Taeko Fukutani, Shigeaki Toratani, Taku Kanda, Kensaku Matsui, Sachiko Yamasaki, Kensaku Sumi, Ikuko Ogawa, Souichi Yanamoto

Int J Environ Res Public Health. 2022 Apr; 19(8): 4702. Published online 2022 Apr 13. doi: 10.3390/ijerph19084702

PMCID:: PMC9030668

Abstract Article PDF–5.9M

Select item 901846716.

GLI1 Gene Alterations in Neoplasms of the Genitourinary and Gynecologic Tract

Pedram Argani, Baris Boyraz, Esther Oliva, Andres Matoso, John Gross, Eddie Fridman, Lei Zhang, Brendan C. Dickson, Cristina R. Antonescu

Am J Surg Pathol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Am J Surg Pathol. 2022 May 1; 46(5): 677–687. doi: 10.1097/PAS.0000000000001844

PMCID:: PMC9018467

Abstract Article PDF–4.2M

Select item 893450117.

GSK-3β suppression upregulates Gli1 to alleviate osteogenesis inhibition in titanium nanoparticle-induced osteolysis

Qing Wang, Wei Zhang, Xiaole Peng, Yunxia Tao, Ye Gu, Wenming Li, Xiaolong Liang, Liangliang Wang, Zerui Wu, Tianhao Wang, Haifeng Zhang, Xin Liu, Yaozeng Xu, Yu Liu, Jun Zhou, Dechun Geng

J Nanobiotechnology. 2022; 20: 148. Published online 2022 Mar 19. doi: 10.1186/s12951-022-01351-7

PMCID:: PMC8934501

Abstract Article PDF–18M

Select item 888884218.

A Critical Function for the Transcription Factors GLI1 and GLI2 in the Proliferation and Survival of Human Mast Cells

Guido Hernan Falduto, Annika Pfeiffer, Qunshu Zhang, Yuzhi Yin, Dean Darrel Metcalfe, Ana Olivera

Front Immunol. 2022; 13: 841045. Published online 2022 Feb 16. doi: 10.3389/fimmu.2022.841045

PMCID:: PMC8888842

Abstract Article PDF–4.1M

Select item 860630619.

Hedgehog Transcriptional Effector GLI Mediates mTOR-Induced PD-L1 Expression in Gastric Cancer Organoids

Vivien Koh, Jayati Chakrabarti, Meaghan Torvund, Nina Steele, Jennifer A. Hawkins, Yoshiaki Ito, Jiang Wang, Michael A. Helmrath, Juanita L. Merchant, Syed Ahmed, Asim Shabbir, Jimmy Bok Yan So, Wei Peng Yong, Yana Zavros

Cancer Lett. Author manuscript; available in PMC 2022 Apr 10.

Published in final edited form as: Cancer Lett. 2021 Oct 10; 518: 59–71. Published online 2021 Jun 12. doi: 10.1016/j.canlet.2021.06.007

PMCID:: PMC8606306

Abstract Article PDF–2.0M

Select item 853898720.

The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells

Ignazia Tusa, Sinforosa Gagliardi, Alessandro Tubita, Silvia Pandolfi, Alessio Menconi, Matteo Lulli, Persio Dello Sbarba, Barbara Stecca, Elisabetta Rovida

Int J Mol Sci. 2021 Oct; 22(20): 11259. Published online 2021 Oct 19. doi: 10.3390/ijms222011259