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Select item 107005391.

Variation in presepsin and thrombomodulin levels for predicting COVID-19 mortality

Azusa Yamazaki, Yoko Nukui, Takahiro Kameda, Ryoichi Saito, Yuki Koda, Naoya Ichimura, Shuji Tohda, Ryunosuke Ohkawa

Sci Rep. 2023; 13: 21493. Published online 2023 Dec 6. doi: 10.1038/s41598-023-48633-0

PMCID:: PMC10700539

Abstract Article PDF–2.7M

Select item 100339372.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 94270963.

How thrombomodulin enables W215A/E217A thrombin to cleave protein C but not fibrinogen

Riley B. Peacock, Taylor McGrann, Sofia Zaragoza, Elizabeth A. Komives

Biochemistry. Author manuscript; available in PMC 2022 Aug 30.

Published in final edited form as: Biochemistry. 2022 Jan 18; 61(2): 77–84. Published online 2022 Jan 3. doi: 10.1021/acs.biochem.1c00635

PMCID:: PMC9427096

Abstract Article PDF–1.4M

Select item 92930804.

Thrombomodulin in patients with mild to moderate bleeding tendency

Dino Mehic, Alexander Tolios, Stefanie Hofer, Cihan Ay, Helmuth Haslacher, Kate Downes, Matthias Haimel, Ingrid Pabinger, Johanna Gebhart

Haemophilia. 2021 Nov; 27(6): 1028–1036. Published online 2021 Oct 10. doi: 10.1111/hae.14433

PMCID:: PMC9293080

Abstract Article PDF–384K

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 89515566.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 88235597.

Association study of polymorphism in Thrombomodulin gene (rs1042579) with cardiovascular disease

Elham Khosravi, Ladan Sadeghian, Parisa Mohamadynejad, Minoo Dianatkhah, Mahsa Hajizadeh, Mojgan Gharipour

Acta Biomed. 2021; 92(6): e2021282. Published online 2022 Jan 19. doi: 10.23750/abm.v92i6.9622

PMCID:: PMC8823559

Abstract Article PDF–1.0M

Select item 87560778.

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs

Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma, Jowaly Schneider, John T. Skinner, Beejan Asady, Erin Goerlich, Marc K. Halushka, Allison G. Hays, Deok-Ho Kim, Chirag R. Parikh, Avi Z. Rosenberg, Isabelle Coppens, Roger A. Johns, Nisha A. Gilotra, Jody E. Hooper, Andrew Pekosz, Daniela Čiháková

EBioMedicine. 2022 Jan; 75: 103812. Published online 2022 Jan 13. doi: 10.1016/j.ebiom.2022.103812

PMCID:: PMC8756077

Abstract Article PDF–4.4M

Select item 85089799.

Cilostazol Induces eNOS and TM Expression via Activation with Sirtuin 1/Krüppel-like Factor 2 Pathway in Endothelial Cells

Chih-Hsien Wu, Yi-Lin Chiu, Chung-Yueh Hsieh, Guo-Shiang Tsung, Lian-Shan Wu, Cheng-Chung Cheng, Tsung-Neng Tsai

Int J Mol Sci. 2021 Oct; 22(19): 10287. Published online 2021 Sep 24. doi: 10.3390/ijms221910287

PMCID:: PMC8508979

Abstract Article PDF–5.0M

Select item 827818510.

Recombinant human thrombomodulin for pneumonia-induced severe ARDS complicated by DIC in children: a preliminary study

Naoyuki Hirata, Dong Tien Ngo, Phuc Huu Phan, Akira Ainai, Thuy Thi Bich Phung, Tuan Anh Ta, Jin Takasaki, Shoji Kawachi, Hiroyuki Nunoi, Noriko Nakajima, Tran Minh Dien

J Anesth. 2021; 35(5): 638–645. Published online 2021 Jul 14. doi: 10.1007/s00540-021-02971-3

PMCID:: PMC8278185

Abstract Article PDF–803K

Select item 825790711.

Thrombomodulin gene polymorphism and the occurrence and prognostic value of sepsis acute kidney injury

Qin Li, Wenjuan Yang, Keming Zhao, Xifeng Sun, Liuqian Bao

Medicine (Baltimore) 2021 Jul 2; 100(26): e26293. Published online 2021 Jul 2. doi: 10.1097/MD.0000000000026293

PMCID:: PMC8257907

Abstract Article PDF–539K

Select item 798040912.

Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells

Hemant Giri, Sumith R. Panicker, Xiaofeng Cai, Indranil Biswas, Hartmut Weiler, Alireza R. Rezaie

Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2022248118. Published online 2021 Mar 8. doi: 10.1073/pnas.2022248118

PMCID:: PMC7980409

Abstract Article PDF–2.0M

Select item 795239613.

Thrombomodulin is upregulated in the kidneys of women with pre-eclampsia

Cleo C. L. van Aanhold, Manon Bos, Katrina M. Mirabito Colafella, Marie-Louise P. van der Hoorn, Ron Wolterbeek, Jan A. Bruijn, Kitty W. M. Bloemenkamp, Anton H. van den Meiracker, A. H. Jan Danser, Hans J. Baelde

Sci Rep. 2021; 11: 5692. Published online 2021 Mar 11. doi: 10.1038/s41598-021-85040-9

PMCID:: PMC7952396

Abstract Article PDF–4.1M

Select item 720606914.

Fractionated radiation suppresses Kruppel-like factor 2 pathway to a greater extent than by single exposure to the same total dose

Ratan Sadhukhan, Justin W. C. Leung, Sarthak Garg, Kimberly J. Krager, Alena V. Savenka, Alexei G. Basnakian, Rupak Pathak

Sci Rep. 2020; 10: 7734. Published online 2020 May 7. doi: 10.1038/s41598-020-64672-3

PMCID:: PMC7206069

Abstract Article PDF–2.0M

Select item 716998315.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 695241116.

Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10)

Michela Comi, Daniele Avancini, Francesca Santoni de Sio, Matteo Villa, Molly Javier Uyeda, Matteo Floris, Daniela Tomasoni, Alessandro Bulfone, Maria Grazia Roncarolo, Silvia Gregori

Cell Mol Immunol. 2020 Jan; 17(1): 95–107. Published online 2019 Mar 6. doi: 10.1038/s41423-019-0218-0