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Items: 1 to 20 of 89

1.
Mutation of the TGN1412 anti‐CD28 monoclonal antibody lower hinge confers specific FcγRIIb binding and retention of super‐agonist activity
Alicia M Chenoweth, Sandra Esparon, Bruce D Wines, Janine Schuurman, Aran F Labrijn, P Mark Hogarth
Immunol Cell Biol. 2023 Aug; 101(7): 657–662. Published online 2023 Apr 28. doi: 10.1111/imcb.12646
PMCID:
PMC10952187
AbstractArticlePDF–649K
2.
FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment
David A. Knorr, Lucas Blanchard, Rom S. Leidner, Shawn M. Jensen, Ryan Meng, Andrew Jones, Carmen Ballesteros-Merino, Richard B. Bell, Maria Baez, Alessandra Marino, David Sprott, Carlo B. Bifulco, Brian Piening, Rony Dahan, Juan C. Osorio, Bernard A. Fox, Jeffrey V. Ravetch
Cancer Immunol Res. 2024 Mar 4; 12(3): 322–333. Published online 2023 Dec 26. doi: 10.1158/2326-6066.CIR-23-0389
PMCID:
PMC10911703
AbstractArticlePDF–3.3M
3.
C-reactive protein impairs immune response of CD8+ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma
Jinxing Jiang, Ziyi Peng, Junying Wang, Mengping Chen, Yike Wan, Honghui Huang, Zhiqiang Liu, Jingya Wang, Jian Hou
J Immunother Cancer. 2023; 11(10): e007593. Published online 2023 Oct 15. doi: 10.1136/jitc-2023-007593
Correction in:
J Immunother Cancer. 2023; 11(12): e007593corr1.
PMCID:
PMC10582887
AbstractArticlePDF–5.1M
4.
FCGR2B as a prognostic and immune microenvironmental marker for gliomas based on transcriptomic analysis
Zhimin Sun, Xiaoli Sun, Yaqin Yuan, Hongsheng Li, Xiaona Li, Zhigang Yao
Medicine (Baltimore) 2023 Sep 15; 102(37): e35084. Published online 2023 Sep 15. doi: 10.1097/MD.0000000000035084
PMCID:
PMC10508392
AbstractArticlePDF–5.1M
5.
FCGR2A as one novel potential target for poor survival prognosis of clear cell renal cell carcinoma
Taozhu Fu, Lianfeng Zhang, Meini Zuo, Feng Li, Changjin Shi, Hongrun Chen
Medicine (Baltimore) 2023 Mar 17; 102(11): e33324. Published online 2023 Mar 17. doi: 10.1097/MD.0000000000033324
PMCID:
PMC10019103
AbstractArticlePDF–2.1M
6.
Inhibitory Fcγ Receptor and Paired Immunoglobulin Type 2 Receptor Alpha Genotypes in Alzheimer’s Disease
Janardan P. Pandey, Aryan M. Namboodiri, Paul J. Nietert, Lisa L. Barnes, David A. Bennett
J Alzheimers Dis. Author manuscript; available in PMC 2022 May 2.
Published in final edited form as: J Alzheimers Dis. 2021; 84(3): 965–968. doi: 10.3233/JAD-215174
PMCID:
PMC9059170
AbstractArticlePDF–302K
7.
FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape
Lei Wu, Yanquan Xu, Huakan Zhao, Yu Zhou, Yu Chen, Shuai Yang, Juan Lei, Jiangang Zhang, Jingchun Wang, Yongzhong Wu, Yongsheng Li
Theranostics. 2022; 12(2): 842–858. Published online 2022 Jan 1. doi: 10.7150/thno.66575
PMCID:
PMC8692894
AbstractArticlePDF–3.9M
8.
Impacts of FcγRIIB and FcγRIIIA gene polymorphisms on systemic lupus erythematous disease activity index
Mansoor Karimifar, Khosro Akbari, Reza ArefNezhad, Farshid Fathi, Mohammad Moosaeepour, Hossein Motedayyen
BMC Res Notes. 2021; 14: 455. Published online 2021 Dec 18. doi: 10.1186/s13104-021-05868-2
Correction in:
BMC Res Notes. 2022; 15: 246.
PMCID:
PMC8684074
AbstractArticlePDF–813K
9.
The association between Fc gamma RIIb expression levels and chronic hepatitis B virus infection progression
Jinglan Jin, Yuwei Liu, Xiaotong Xu, Zhongfeng Wang, Junqi Niu
BMC Infect Dis. 2021; 21: 1235. Published online 2021 Dec 8. doi: 10.1186/s12879-021-06918-7
PMCID:
PMC8653572
AbstractArticlePDF–1.5M
10.
Homogeneously high expression of CD32b makes it a potential target for CAR-T therapy for chronic lymphocytic leukemia
Guoling Wang, Xiaolei Sun, Shiyu Zuo, Chuo Li, Qing Niu, Yonghui Xia, Yuan Meng, Min Liu, Zihao Fang, Xi Yang, Yanyu Jiang, Sheng Wang, Haidong Cui, Huifang Huang, Erlie Jiang, Dongming Zhou, Qi Deng, Jing Pan, Xiaoming Feng
J Hematol Oncol. 2021; 14: 149. Published online 2021 Sep 16. doi: 10.1186/s13045-021-01160-9
PMCID:
PMC8447616
AbstractArticlePDF–1.4M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
Accelerated clearance and degradation of cell free HIV by neutralizing antibodies occurs via FcγRIIb on liver sinusoidal endothelial cells by endocytosis
James M. Turman, Alana M. Cheplowitz, Charu Tiwari, Thushara Thomas, Dhruvi Joshi, Menakshi Bhat, Qian Wu, Erik Pong, Seung Y. Chu, David E. Szymkowski, Amit Sharma, Stephanie Seveau, John M. Robinson, Jesse J. Kwiek, Dennis Burton, Murugesan VS. Rajaram, Jonghan Kim, Lars Hangartner, Latha P. Ganesan
J Immunol. Author manuscript; available in PMC 2022 Mar 15.
Published in final edited form as: J Immunol. 2021 Mar 15; 206(6): 1284–1296. Published online 2021 Feb 10. doi: 10.4049/jimmunol.2000772
PMCID:
PMC7946731
AbstractArticlePDF–2.6M
13.
FcγRIIB is a T cell checkpoint in antitumor immunity
Clara R. Farley, Anna B. Morris, Marvi Tariq, Kelsey B. Bennion, Sayalee Potdar, Ragini Kudchadkar, Michael C. Lowe, Mandy L. Ford
JCI Insight. 2021 Feb 22; 6(4): e135623. Published online 2021 Feb 22. doi: 10.1172/jci.insight.135623
PMCID:
PMC7934918
AbstractArticlePDF–1.5M
14.
FcγRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis
Stephanie Trend, Jonatan Leffler, Ingrid Teige, Björn Frendéus, Allan G. Kermode, Martyn A. French, Prue H. Hart
Front Immunol. 2020; 11: 614492. Published online 2021 Jan 11. doi: 10.3389/fimmu.2020.614492
PMCID:
PMC7832177
AbstractArticlePDF–3.7M
15.
Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus
Linlin Sheng, Xiuqin Cao, Shuhong Chi, Jing Wu, Huihui Xing, Huiyu Liu, Zhiwei Yang
Int J Mol Med. 2020 Oct; 46(4): 1409–1422. Published online 2020 Aug 7. doi: 10.3892/ijmm.2020.4698
PMCID:
PMC7447306
AbstractArticlePDF–1.3M
16.
Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis
Heike Danzer, Joachim Glaesner, Anne Baerenwaldt, Carmen Reitinger, Anja Lux, Lukas Heger, Diana Dudziak, Thomas Harrer, André Gessner, Falk Nimmerjahn
eLife. 2020; 9: e55319. Published online 2020 Jul 2. doi: 10.7554/eLife.55319
PMCID:
PMC7438111
AbstractArticlePDF–1010K
17.
Signaling through the inhibitory Fc receptor FcγRIIB induces CD8 T cell apoptosis to limit T cell immunity
Anna B. Morris, Clara R. Farley, David F. Pinelli, Layne E. Adams, Mark S. Cragg, Jeremy M. Boss, Christopher D. Scharer, Miguel Fribourg, Paolo Cravedi, Peter S. Heeger, Mandy L. Ford
Immunity. Author manuscript; available in PMC 2021 Jan 14.
Published in final edited form as: Immunity. 2020 Jan 14; 52(1): 136–150.e6. doi: 10.1016/j.immuni.2019.12.006
PMCID:
PMC7326381
AbstractArticlePDF–2.7M
18.
The Complex Association of FcγRIIb With Autoimmune Susceptibility
J. Sjef Verbeek, Sachiko Hirose, Hiroyuki Nishimura
Front Immunol. 2019; 10: 2061. Published online 2019 Oct 15. doi: 10.3389/fimmu.2019.02061
PMCID:
PMC6803437
AbstractArticlePDF–3.4M
19.
IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma
Yunmian Liu, Chunyan Song, Faping Shen, Jing Zhang, Sonya Wei Song
PLoS One. 2019; 14(9): e0222999. Published online 2019 Sep 27. doi: 10.1371/journal.pone.0222999
PMCID:
PMC6764691
AbstractArticlePDF–2.7M
20.
FcγRIIB-I232T polymorphic change allosterically suppresses ligand binding
Wei Hu, Yong Zhang, Xiaolin Sun, Tongtong Zhang, Liling Xu, Hengyi Xie, Zhanguo Li, Wanli Liu, Jizhong Lou, Wei Chen
eLife. 2019; 8: e46689. Published online 2019 Jul 25. doi: 10.7554/eLife.46689
PMCID:
PMC6711707
AbstractArticlePDF–2.6M

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