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Items: 1 to 20 of 33

1.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
When transcripts matter: delineating between non-syndromic hearing loss DFNB32 and hearing impairment infertile male syndrome (HIIMS)
Marzieh Mohseni, Mojdeh Akbari, Kevin T Booth, Mojgan Babanejad, Hela Azaiez, Fariba Ardalani, Sanaz Arzhangi, Khadijeh Jalalvand, Nooshin Nikzat, Fatemeh Ghodratpour, payman jamali, Omid Ali Adeli, Haleh Habibi, Kimia Kahrizi, Hossein Najmabadi
J Hum Genet. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: J Hum Genet. 2020 Jul; 65(7): 609–617. Published online 2020 Mar 30. doi: 10.1038/s10038-020-0740-z
PMCID:
PMC7651993
AbstractArticlePDF–451K
4.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
5.
Novel Loss-of-Function Variants in CDC14A are Associated with Recessive Sensorineural Hearing Loss in Iranian and Pakistani Patients
Julia Doll, Susanne Kolb, Linda Schnapp, Aboulfazl Rad, Franz Rüschendorf, Imran Khan, Abolfazl Adli, Atefeh Hasanzadeh, Daniel Liedtke, Sabine Knaup, Michaela AH Hofrichter, Tobias Müller, Marcus Dittrich, Il-Keun Kong, Hyung-Goo Kim, Thomas Haaf, Barbara Vona
Int J Mol Sci. 2020 Jan; 21(1): 311. Published online 2020 Jan 2. doi: 10.3390/ijms21010311
PMCID:
PMC6982189
AbstractArticlePDF–1.8M
6.
The human phosphatase CDC14A modulates primary cilium length by regulating centrosomal actin nucleation
Borhan Uddin, Patrick Partscht, Nan‐Peng Chen, Annett Neuner, Manuel Weiß, Robert Hardt, Aliakbar Jafarpour, Bernd Heßling, Thomas Ruppert, Holger Lorenz, Gislene Pereira, Elmar Schiebel
EMBO Rep. 2019 Jan; 20(1): e46544. Published online 2018 Nov 22. doi: 10.15252/embr.201846544
PMCID:
PMC6322383
AbstractArticlePDF–2.4M
7.
Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1
Sara Ovejero, Patricia Ayala, Marcos Malumbres, Felipe X. Pimentel-Muiños, Avelino Bueno, María P. Sacristán
Sci Rep. 2018; 8: 11871. Published online 2018 Aug 8. doi: 10.1038/s41598-018-30253-8
PMCID:
PMC6082843
AbstractArticlePDF–4.6M
8.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
9.
CDC14A phosphatase is essential for hearing and male fertility in mouse and human
Ayesha Imtiaz, Inna A Belyantseva, Alisha J Beirl, Cristina Fenollar-Ferrer, Rasheeda Bashir, Ihtisham Bukhari, Amal Bouzid, Uzma Shaukat, Hela Azaiez, Kevin T Booth, Kimia Kahrizi, Hossein Najmabadi, Azra Maqsood, Elizabeth A Wilson, Tracy S Fitzgerald, Abdelaziz Tlili, Rafal Olszewski, Merete Lund, Taimur Chaudhry, Atteeq U Rehman, Matthew F Starost, Ali M Waryah, Michael Hoa, Lijin Dong, Robert J Morell, Richard J H Smith, Sheikh Riazuddin, Saber Masmoudi, Katie S Kindt, Sadaf Naz, Thomas B Friedman
Hum Mol Genet. 2018 Mar 1; 27(5): 780–798. Published online 2017 Dec 23. doi: 10.1093/hmg/ddx440
PMCID:
PMC6059191
AbstractArticlePDF–2.0M
10.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
11.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
12.
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling
Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika
J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065
PMCID:
PMC5548413
AbstractArticlePDF–5.2M
13.
Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm
Nan-Peng Chen, Borhan Uddin, Robert Hardt, Wen Ding, Marko Panic, Ilaria Lucibello, Patricia Kammerer, Thomas Ruppert, Elmar Schiebel
Proc Natl Acad Sci U S A. 2017 May 16; 114(20): 5201–5206. Published online 2017 May 2. doi: 10.1073/pnas.1619356114
PMCID:
PMC5441781
AbstractArticlePDF–1.5M
14.
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
Rohith Srivas, John Paul Shen, Chih Cheng Yang, Su Ming Sun, Jianfeng Li, Andrew M. Gross, James Jensen, Katherine Licon, Ana Bojorquez-Gomez, Kristin Klepper, Justin Huang, Daniel Pekin, Jia L. Xu, Huwate Yeerna, Vignesh Sivaganesh, Leonie Kollenstart, Haico van Attikum, Pedro Aza-Blanc, Robert W. Sobol, Trey Ideker
Mol Cell. Author manuscript; available in PMC 2017 Aug 4.
Published in final edited form as: Mol Cell. 2016 Aug 4; 63(3): 514–525. Published online 2016 Jul 21. doi: 10.1016/j.molcel.2016.06.022
PMCID:
PMC5209245
AbstractArticlePDF–1.6M
15.
Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness
Sedigheh Delmaghani, Asadollah Aghaie, Yosra Bouyacoub, Hala El Hachmi, Crystel Bonnet, Zied Riahi, Sebastien Chardenoux, Isabelle Perfettini, Jean-Pierre Hardelin, Ahmed Houmeida, Philippe Herbomel, Christine Petit
Am J Hum Genet. 2016 Jun 2; 98(6): 1266–1270. Published online 2016 Jun 2. doi: 10.1016/j.ajhg.2016.04.015
PMCID:
PMC4908234
AbstractArticlePDF–1.6M
16.
Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion
Nan-Peng Chen, Borhan Uddin, Renate Voit, Elmar Schiebel
Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4): 990–995. Published online 2016 Jan 8. doi: 10.1073/pnas.1515605113
PMCID:
PMC4743822
AbstractArticlePDF–1.2M
17.
Human Cdc14A regulates Wee1 stability by counteracting CDK-mediated phosphorylation
Sara Ovejero, Patricia Ayala, Avelino Bueno, María P. Sacristán
Mol Biol Cell. 2012 Dec 1; 23(23): 4515–4525. doi: 10.1091/mbc.E12-04-0260
PMCID:
PMC3510014
AbstractArticlePDF–1.6M
18.
Cdc14 Phosphatases Preferentially Dephosphorylate a Subset of Cyclin-dependent kinase (Cdk) Sites Containing Phosphoserine
Steven C. Bremmer, Hana Hall, Juan S. Martinez, Christie L. Eissler, Thomas H. Hinrichsen, Sandra Rossie, Laurie L. Parker, Mark C. Hall, Harry Charbonneau
J Biol Chem. 2012 Jan 13; 287(3): 1662–1669. Published online 2011 Nov 23. doi: 10.1074/jbc.M111.281105
PMCID:
PMC3265848
AbstractArticlePDF–1.9M
19.
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription
Andres Clemente-Blanco, Nicholas Sen, Maria Mayan-Santos, Maria P. Sacristán, Bryony Graham, Adam Jarmuz, Adam Giess, Elizabeth Webb, Laurence Game, Dirk Eick, Avelino Bueno, Matthias Merkenschlager, Luis Aragón
Nat Cell Biol. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Nat Cell Biol. 2011 Oct 23; 13(12): 1450–1456. Published online 2011 Oct 23. doi: 10.1038/ncb2365
PMCID:
PMC3232454
AbstractArticlePDF–1.3M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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