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Select item 94199461.

Enhanced Myogenesis by Silencing Myostatin with Nonviral Delivery of a dCas9 Ribonucleoprotein Complex

Yinwei Chen, Lia Banie, Benjamin N. Breyer, Yan Tan, Zhao Wang, Feng Zhou, Guifang Wang, Guiting Lin, Jihong Liu, Lei S. Qi, Tom F. Lue

CRISPR J. August 2022; 5(4): 598–608. Published online 2022 Aug 12. doi: 10.1089/crispr.2022.0009

PMCID:: PMC9419946

Abstract Article PDF–1.4M

Select item 84651182.

Renal Ischemia/Reperfusion Early Induces Myostatin and PCSK9 Expression in Rat Kidneys and HK-2 Cells

Chiara Barisione, Daniela Verzola, Silvano Garibaldi, Pier Francesco Ferrari, Giacomo Garibotto, Pietro Ameri, Bianca Pane, Giovanni Spinella, Giovanni Pratesi, Domenico Palombo

Int J Mol Sci. 2021 Sep; 22(18): 9884. Published online 2021 Sep 13. doi: 10.3390/ijms22189884

PMCID:: PMC8465118

Abstract Article PDF–7.4M

Select item 75859123.

Myostatin in the Arterial Wall of Patients with End-Stage Renal Disease

Pasquale Esposito, Daniela Verzola, Edoardo La Porta, Samantha Milanesi, Maria Antonietta Grignano, Alessandro Avella, Marilena Gregorini, Massimo Abelli, Elena Ticozzelli, Teresa Rampino, Giacomo Garibotto

J Atheroscler Thromb. 2020 Oct 1; 27(10): 1039–1052. doi: 10.5551/jat.51144

PMCID:: PMC7585912

Abstract Article PDF–4.2M

Select item 64041004.

Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury

Johanna Magga, Laura Vainio, Teemu Kilpiö, Juha J. Hulmi, Saija Taponen, Ruizhu Lin, Markus Räsänen, Zoltán Szabó, Erhe Gao, Lea Rahtu-Korpela, Tarja Alakoski, Johanna Ulvila, Mika Laitinen, Arja Pasternack, Walter J. Koch, Kari Alitalo, Riikka Kivelä, Olli Ritvos, Risto Kerkelä

Mol Ther. 2019 Mar 6; 27(3): 600–610. Published online 2019 Jan 24. doi: 10.1016/j.ymthe.2019.01.013

PMCID:: PMC6404100

Abstract Article PDF–1.9M

Select item 57938015.

Structure of the human myostatin precursor and determinants of growth factor latency

Thomas R Cotton, Gerhard Fischer, Xuelu Wang, Jason C McCoy, Magdalena Czepnik, Thomas B Thompson, Marko Hyvönen

EMBO J. 2018 Feb 1; 37(3): 367–383. Published online 2018 Jan 12. doi: 10.15252/embj.201797883

PMCID:: PMC5793801

Abstract Article PDF–2.6M

Select item 55368746.

Myostatin-like proteins regulate synaptic function and neuronal morphology

Hrvoje Augustin, Kieran McGourty, Joern R. Steinert, Helena M. Cochemé, Jennifer Adcott, Melissa Cabecinha, Alec Vincent, Els F. Halff, Josef T. Kittler, Emmanuel Boucrot, Linda Partridge

Development. 2017 Jul 1; 144(13): 2445–2455. doi: 10.1242/dev.152975

PMCID:: PMC5536874

Abstract Article

Select item 53366967.

Structural basis for potency differences between GDF8 and GDF11

Ryan G. Walker, Magdalena Czepnik, Erich J. Goebel, Jason C. McCoy, Ana Vujic, Miook Cho, Juhyun Oh, Senem Aykul, Kelly L. Walton, Gauthier Schang, Daniel J. Bernard, Andrew P. Hinck, Craig A. Harrison, Erik Martinez-Hackert, Amy J. Wagers, Richard T. Lee, Thomas B. Thompson

BMC Biol. 2017; 15: 19. Published online 2017 Mar 3. doi: 10.1186/s12915-017-0350-1

PMCID:: PMC5336696

Abstract Article PDF–8.2M

Select item 50586148.

Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody

James R. Apgar, Michelle Mader, Rita Agostinelli, Susan Benard, Peter Bialek, Mark Johnson, Yijie Gao, Mark Krebs, Jane Owens, Kevin Parris, Michael St. Andre, Kris Svenson, Carl Morris, Lioudmila Tchistiakova

MAbs. 2016 Oct; 8(7): 1302–1318. Published online 2016 Sep 13. doi: 10.1080/19420862.2016.1215786

PMCID:: PMC5058614

Abstract Article PDF–1.4M

Select item 44057589.

Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats

Christopher L Mendias, Evan B Lynch, Jonathan P Gumucio, Michael D Flood, Danielle S Rittman, Douglas W Van Pelt, Stuart M Roche, Carol S Davis

J Physiol. 2015 Apr 15; 593(Pt 8): 2037–2052. Published online 2015 Feb 25. doi: 10.1113/jphysiol.2014.287144

PMCID:: PMC4405758

Abstract Article PDF–2.5M

Select item 390683010.

Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2

György Szláma, Mária Trexler, László Patthy

FEBS J. 2013 Aug; 280(16): 3822–3839. Published online 2013 Jul 5. doi: 10.1111/febs.12377

PMCID:: PMC3906830

Abstract Article PDF–684K

Select item 369950511.

Inhibition of Myostatin Signaling through Notch Activation following Acute Resistance Exercise

Matthew G. MacKenzie, David Lee Hamilton, Mark Pepin, Amy Patton, Keith Baar

PLoS One. 2013; 8(7): e68743. Published online 2013 Jul 2. doi: 10.1371/journal.pone.0068743

PMCID:: PMC3699505

Abstract Article PDF–871K

Select item 369040212.

The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy

Valentina Proserpio, Raffaella Fittipaldi, James G. Ryall, Vittorio Sartorelli, Giuseppina Caretti

Genes Dev. 2013 Jun 1; 27(11): 1299–1312. doi: 10.1101/gad.217240.113

PMCID:: PMC3690402

Abstract Article PDF–2.4M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304475314.

Effect of Myostatin Depletion on Weight Gain, Hyperglycemia, and Hepatic Steatosis during Five Months of High-Fat Feeding in Mice

Kerri Burgess, Tianshun Xu, Roger Brown, Bajin Han, Stephen Welle

PLoS One. 2011; 6(2): e17090. Published online 2011 Feb 24. doi: 10.1371/journal.pone.0017090

PMCID:: PMC3044753

Abstract Article PDF–419K

Select item 285385815.

L6E9 Myoblasts Are Deficient of Myostatin and Additional TGF-β Members Are Candidates to Developmentally Control Their Fiber Formation

Stefania Rossi, Elena Stoppani, Massimiliano Gobbo, Anna Caroli, Alessandro Fanzani

J Biomed Biotechnol. 2010; 2010: 326909. Published online 2010 Apr 13. doi: 10.1155/2010/326909

PMCID:: PMC2853858

Abstract Article PDF–3.0M

Select item 283856816.

High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo

Michiko Yamada, Ryuichi Tatsumi, Keitaro Yamanouchi, Tohru Hosoyama, Sei-ichi Shiratsuchi, Akiko Sato, Wataru Mizunoya, Yoshihide Ikeuchi, Mitsuhiro Furuse, Ronald E. Allen

Am J Physiol Cell Physiol. 2010 Mar; 298(3): C465–C476. Published online 2009 Dec 9. doi: 10.1152/ajpcell.00449.2009

PMCID:: PMC2838568

Abstract Article

Select item 281272817.

Myostatin and follistatin expression in skeletal muscles of rats with chronic heart failure

Aline Regina Ruiz Lima, Paula Felippe Martinez, Katashi Okoshi, Daniele Mendes Guizoni, Leonardo A Mamede Zornoff, Dijon Henrique Salomé Campos, Sílvio Assis Oliveira Jr, Camila Bonomo, Maeli Dal Pai-Silva, Marina Politi Okoshi

Int J Exp Pathol. 2010 Feb; 91(1): 54–62. doi: 10.1111/j.1365-2613.2009.00683.x