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Select item 98256611.

Protein Kinase G2 Is Essential for Skeletal Homeostasis and Adaptation to Mechanical Loading in Male but not Female Mice

Hema Kalyanaraman, Shyamsundar Pal China, Justin A. Cabriales, Jafar Moininazeri, Darren E. Casteel, Julian J. Garcia, Van W. Wong, Albert Chen, Robert L. Sah, Gerry R. Boss, Renate B. Pilz

J Bone Miner Res. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Bone Miner Res. 2023 Jan; 38(1): 171–185. Published online 2022 Nov 27. doi: 10.1002/jbmr.4746

PMCID:: PMC9825661

Abstract Article PDF–2.6M

Select item 93362182.

Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease

Peng Yin, Qiong Liu, Yongcheng Pan, Weili Yang, Su Yang, Wenjie Wei, Xingxing Chen, Yan Hong, Dazhang Bai, Xiao‐Jiang Li, Shihua Li

EMBO Rep. 2020 Jun 4; 21(6): e49783. Published online 2020 Apr 9. doi: 10.15252/embr.201949783

PMCID:: PMC9336218

Abstract Article PDF–2.1M

Select item 92347603.

Type-2 cGMP-dependent protein kinase suppresses proliferation and carcinogenesis in the colon epithelium

Bianca N Islam, Sarah K Sharman, Yali Hou, Rui Wang, Justin Ashby, Honglin Li, Kebin Liu, Kenneth J Vega, Darren D Browning

Carcinogenesis. 2022 Jun; 43(6): 584–593. Published online 2022 Feb 21. doi: 10.1093/carcin/bgac022

PMCID:: PMC9234760

Abstract Article PDF–71M

Select item 85022514.

Loss of cGMP-dependent protein kinase II alters ultrasonic vocalizations in mice, a model for speech impairment in human microdeletion 4q21 syndrome

Tiffany M. Tran, Jessica K. Sherwood, Michael J. Doolittle, Matheus F. Sathler, Franz Hofmann, Leslie M. Stone-Roy, Seonil Kim

Neurosci Lett. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Neurosci Lett. 2021 Aug 10; 759: 136048. Published online 2021 Jun 12. doi: 10.1016/j.neulet.2021.136048

PMCID:: PMC8502251

Abstract Article PDF–1.0M

Select item 67823785.

Long-Term Potentiation in the Hippocampal CA1 Region of Mice Lacking cGMP-Dependent Kinases Is Normal and Susceptible to Inhibition of Nitric Oxide Synthase

Thomas Kleppisch, Alexander Pfeifer, Peter Klatt, Peter Ruth, Alexandra Montkowski, Reinhard Fässler, Franz Hofmann

J Neurosci. 1999 Jan 1; 19(1): 48–55. doi: 10.1523/JNEUROSCI.19-01-00048.1999

PMCID:: PMC6782378

Abstract Article PDF–290K

Select item 62870896.

Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent

Idoia Quintana-Urzainqui, Zrinko Kozić, Soham Mitra, Tian Tian, Martine Manuel, John O. Mason, David J. Price

iScience. 2018 Dec 21; 10: 171–191. Published online 2018 Nov 22. doi: 10.1016/j.isci.2018.11.031

PMCID:: PMC6287089

Abstract Article PDF–12M

Select item 60861277.

cGMP-dependent Protein Kinase-2 Regulates Bone Mass and Prevents Diabetic Bone Loss

Ghania Ramdani, Nadine Schall, Hema Kalyanaraman, Nisreen Wahwah, Sahar Moheize, Jenna J. Lee, Robert L. Sah, Alexander Pfeifer, Darren E. Casteel, Renate B. Pilz

J Endocrinol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Endocrinol. 2018 Sep; 238(3): 203–219. Published online 2018 Jun 18. doi: 10.1530/JOE-18-0286

PMCID:: PMC6086127

Abstract Article PDF–1.8M

Select item 53893708.

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Rui Wang, Bianca N. Islam, Allison Bridges, Sarah K. Sharman, Muhan Hu, Yali Hou, Payaningal R. Somanath, Laine Venable, Nagendra Singh, Sangmi Kim, Subbaramiah Sridhar, Franz Hofmann, Darren D. Browning

Am J Pathol. 2017 Feb; 187(2): 377–389. doi: 10.1016/j.ajpath.2016.10.016

PMCID:: PMC5389370

Abstract Article PDF–1.9M

Select item 49472349.

Brain region-specific effects of cGMP-dependent kinase II knockout on AMPA receptor trafficking and animal behavior

Seonil Kim, Joseph E. Pick, Sinedu Abera, Latika Khatri, Danielle D.P. Ferreira, Matheus F. Sathler, Sage L. Morison, Franz Hofmann, Edward B. Ziff

Learn Mem. 2016 Aug; 23(8): 435–441. Published online 2016 Aug. doi: 10.1101/lm.042960.116

PMCID:: PMC4947234

Abstract Article PDF–392K

Select item 485606910.

Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?

Nicolas Navarro, A. Murat Maga

G3 (Bethesda) 2016 May; 6(5): 1153–1163. Published online 2016 Feb 23. doi: 10.1534/g3.115.024372

PMCID:: PMC4856069

Abstract Article PDF–1.4M

Select item 445145511.

cGMP-Dependent Protein Kinase Type II Knockout Mice Exhibit Working Memory Impairments, Decreased Repetitive Behavior, and Increased Anxiety-like Traits

Charlotte M. Wincott, Sinedu Abera, Sarah A. Vunck, Yoon Choi, Roseann F. Titcombe, Shannon O. Antoine, David S. Tukey, Loren M. DeVito, Franz Hofmann, Charles A. Hoeffer, Edward B. Ziff

Neurobiol Learn Mem. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Neurobiol Learn Mem. 2014 Oct; 114: 32–39. Published online 2014 Apr 18. doi: 10.1016/j.nlm.2014.04.007

PMCID:: PMC4451455

Abstract Article PDF–975K

Select item 443324412.

Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues

Stefanie Wolfertstetter, Jörg Reinders, Frank Schwede, Peter Ruth, Elisabeth Schinner, Jens Schlossmann

PLoS One. 2015; 10(5): e0126057. Published online 2015 May 15. doi: 10.1371/journal.pone.0126057

PMCID:: PMC4433244

Abstract Article PDF–2.2M

Select item 436418513.

Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca²⁺-permeable AMPA receptors

Seonil Kim, Roseann F. Titcombe, Hong Zhang, Latika Khatri, Hiwot K. Girma, Franz Hofmann, Ottavio Arancio, Edward B. Ziff

Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10): 3122–3127. Published online 2015 Feb 23. doi: 10.1073/pnas.1417498112

PMCID:: PMC4364185

Abstract Article PDF–1.0M

Select item 430365214.

Cyclic GMP Kinase II (cGKII) Inhibits NHE3 by Altering Its Trafficking and Phosphorylating NHE3 at Three Required Sites: IDENTIFICATION OF A MULTIFUNCTIONAL PHOSPHORYLATION SITE

Tiane Chen, Hetal S. Kocinsky, Boyoung Cha, Rakhilya Murtazina, Jianbo Yang, C. Ming Tse, Varsha Singh, Robert Cole, Peter S. Aronson, Hugo de Jonge, Rafiquel Sarker, Mark Donowitz

J Biol Chem. 2015 Jan 23; 290(4): 1952–1965. Published online 2014 Dec 5. doi: 10.1074/jbc.M114.590174

PMCID:: PMC4303652

Abstract Article PDF–793K

Select item 392855215.

The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells

Salvatore Incontro, Francisco Ciruela, Edward Ziff, Franz Hofmann, José Sánchez-Prieto, Magdalena Torres

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Aug; 1833(8): 1820–1831. Published online 2013 Mar 29. doi: 10.1016/j.bbamcr.2013.03.021

PMCID:: PMC3928552

Abstract Article PDF–3.5M

Select item 392159116.

Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium

R Wang, I-K Kwon, N Singh, B Islam, K Liu, S Sridhar, F Hofmann, D D Browning

Cell Death Differ. 2014 Mar; 21(3): 427–437. Published online 2013 Nov 22. doi: 10.1038/cdd.2013.163

PMCID:: PMC3921591

Abstract Article PDF–3.2M

Select item 357241017.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 354167818.

Spatial Memory Deficits and Motor Coordination Facilitation in cGMP-Dependent Protein Kinase Type II-deficient Mice

Charlotte M. Wincott, Seonil Kim, Roseann F. Titcombe, David S. Tukey, Hiwot K. Girma, Joseph E. Pick, Loren M. DeVito, Franz Hofmann, Charles Hoeffer, Edward Ziff

Neurobiol Learn Mem. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Neurobiol Learn Mem. 2013 Jan; 99: 32–37. Published online 2012 Oct 24. doi: 10.1016/j.nlm.2012.10.003

PMCID:: PMC3541678

Abstract Article PDF–816K

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 309329720.

CYCLIC GMP/PROTEIN KINASE G CONTROL A SRC-CONTAINING MECHANOSOME IN OSTEOBLASTS

Hema Rangaswami, Raphaela Schwappacher, Nisha Marathe, Shunhui Zhuang, Darren E. Casteel, Bodo Haas, Yong Chen, Alexander Pfeifer, Hisashi Kato, Sanford Shattil, Gerry R. Boss, Renate B. Pilz

Sci Signal. Author manuscript; available in PMC 2011 Dec 21.

Published in final edited form as: Sci Signal. 2010 Dec 21; 3(153): ra91. Published online 2010 Dec 21. doi: 10.1126/scisignal.2001423