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Items: 1 to 20 of 47

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
3.
The Role of G Protein-Coupled Receptor Kinase 6 Regulation in Inflammation and Pain
Maike Stegen, Ulrich H. Frey
Int J Mol Sci. 2022 Dec; 23(24): 15880. Published online 2022 Dec 14. doi: 10.3390/ijms232415880
PMCID:
PMC9784940
AbstractArticlePDF–1.6M
4.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
5.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport
Maria Vistrup-Parry, W. Bruce Sneddon, Sofie Bach, Kristian Strømgaard, Peter A. Friedman, Tatyana Mamonova
J Biol Chem. 2021 Jan-Jun; 296: 100473. Published online 2021 Feb 24. doi: 10.1016/j.jbc.2021.100473
PMCID:
PMC8042174
AbstractArticlePDF–1.4M
8.
Characterization of the G protein-coupled receptor kinase 6 promoter reveals a functional CREB binding site
Maike Stegen, Andrea Engler, Crista Ochsenfarth, Iris Manthey, Jürgen Peters, Winfried Siffert, Ulrich H. Frey
PLoS One. 2021; 16(2): e0247087. Published online 2021 Feb 18. doi: 10.1371/journal.pone.0247087
PMCID:
PMC7891717
AbstractArticlePDF–2.6M
9.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
10.
S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson’s disease
Weiwei Wu, Chun Chau Sung, Peichun Yu, Jiahua Li, Kenny K. K. Chung
PLoS One. 2020; 15(4): e0232019. Published online 2020 Apr 28. doi: 10.1371/journal.pone.0232019
Correction in:
PLoS One. 2020; 15(6): e0235296.
PMCID:
PMC7188290
AbstractArticlePDF–3.1M
11.
Hypermethylation of the G protein‐coupled receptor kinase 6 (GRK6) promoter inhibits binding of C/EBPα, and GRK6 knockdown promotes cell migration and invasion in lung adenocarcinoma cells
Sumei Yao, Dandan Wu, Jinliang Chen, Peng Wang, Xuedong Lv, Jianan Huang
FEBS Open Bio. 2019 Apr; 9(4): 605–617. Published online 2019 Mar 19. doi: 10.1002/2211-5463.12606
PMCID:
PMC6443861
AbstractArticlePDF–1.5M
12.
Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability
Hema Adhikari, Christopher M. Counter
Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6
PMCID:
PMC6128905
AbstractArticlePDF–2.2M
13.
Overexpression of G Protein-Coupled Receptor Kinase 6 (GRK6) Is Associated with Progression and Poor Prognosis of Papillary Thyroid Carcinoma
Xiaoqi Che, Guihui Zhang, Xiaojing Zhang, Jie Xue
Med Sci Monit. 2018; 24: 3540–3548. Published online 2018 May 28. doi: 10.12659/MSM.908176
PMCID:
PMC6001367
AbstractArticlePDF–1003K
14.
The association of single nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes
Chad A GROTEGUT, Ms Emily NGAN, Ms Melanie E GARRETT, Marie Lynn MIRANDA, Allison E ASHLEY-KOCH, Geeta K SWAMY
Am J Obstet Gynecol. Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: Am J Obstet Gynecol. 2017 Sep; 217(3): 367.e1–367.e9. Published online 2017 May 17. doi: 10.1016/j.ajog.2017.05.023
PMCID:
PMC5581254
AbstractArticlePDF–695K
15.
c-Src, Insulin-like growth factor I receptor, G-protein-coupled Receptor Kinases and Focal Adhesion Kinase are enriched into Prostate Cancer Cell Exosomes
Rachel M. DeRita, Brad Zerlanko, Amrita Singh, Huimin Lu, Renato V. Iozzo, Jeffrey L. Benovic, Lucia R. Languino
J Cell Biochem. Author manuscript; available in PMC 2018 Jan 1.
Published in final edited form as: J Cell Biochem. 2017 Jan; 118(1): 66–73. Published online 2016 Jul 12. doi: 10.1002/jcb.25611
PMCID:
PMC5552241
AbstractArticlePDF–798K
16.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
17.
Regulation of Oxytocin Receptor Responsiveness by G Protein-Coupled Receptor Kinase 6 in Human Myometrial Smooth Muscle
Jonathon M. Willets, Paul J. Brighton, Rajendra Mistry, Gavin E. Morris, Justin C. Konje, R. A. John Challiss
Mol Endocrinol. August 1, 2009; 23(8): 1272–1280. doi: 10.1210/me.2009-0047
PMCID:
PMC5419184
AbstractArticle
18.
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman
Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387
PMCID:
PMC5260939
AbstractArticlePDF–1.1M
19.
GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal
Qiumin Le, Wenqing Yao, Yuejun Chen, Biao Yan, Cao Liu, Man Yuan, Yuqing Zhou, Lan Ma
Cell Death Dis. 2016 Nov; 7(11): e2478. Published online 2016 Nov 24. doi: 10.1038/cddis.2016.377
PMCID:
PMC5260904
AbstractArticlePDF–1.1M
20.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M

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