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Select item 90427081.

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay

Dev Cell. Author manuscript; available in PMC 2022 Apr 27.

Published in final edited form as: Dev Cell. 2020 Sep 28; 54(6): 710–726.e8. Published online 2020 Jul 22. doi: 10.1016/j.devcel.2020.06.034

PMCID:: PMC9042708

Abstract Article PDF–3.9M

Select item 81226342.

Effects of Whole-Body Adenylyl Cyclase 5 (Adcy5) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

Sebastian Dommel, Anne Hoffmann, Claudia Berger, Matthias Kern, Nora Klöting, Aimo Kannt, Matthias Blüher

Int J Mol Sci. 2021 May; 22(9): 4353. Published online 2021 Apr 21. doi: 10.3390/ijms22094353

PMCID:: PMC8122634

Abstract Article PDF–2.0M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 75755924.

AKAP5 complex facilitates purinergic modulation of vascular L-type Ca²⁺ channel Ca_V1.2

Maria Paz Prada, Arsalan U. Syed, Gopireddy R. Reddy, Miguel Martín-Aragón Baudel, Víctor A. Flores-Tamez, Kent C. Sasse, Sean M. Ward, Padmini Sirish, Nipavan Chiamvimonvat, Peter Bartels, Eamonn J. Dickson, Johannes W. Hell, John D. Scott, Luis F. Santana, Yang K. Xiang, Manuel F. Navedo, Madeline Nieves-Cintrón

Nat Commun. 2020; 11: 5303. Published online 2020 Oct 20. doi: 10.1038/s41467-020-18947-y

PMCID:: PMC7575592

Abstract Article PDF–2.5M

Select item 75637915.

Allosteric Inhibition of Adenylyl Cyclase Type 5 by G-Protein: A Molecular Dynamics Study

Elisa Frezza, Tina-Méryl Amans, Juliette Martin

Biomolecules. 2020 Sep; 10(9): 1330. Published online 2020 Sep 17. doi: 10.3390/biom10091330

PMCID:: PMC7563791

Abstract Article PDF–18M

Select item 72652806.

Host genotype and exercise exhibit species-level selection for members of the gut bacterial communities in the mouse digestive system

R. A. Dowden, L. R. McGuinness, P. J. Wisniewski, S. C. Campbell, J. J. Guers, M. Oydanich, S. F. Vatner, M. M. Häggblom, L. J. Kerkhof

Sci Rep. 2020; 10: 8984. Published online 2020 Jun 2. doi: 10.1038/s41598-020-65740-4

PMCID:: PMC7265280

Abstract Article PDF–9.9M

Select item 71789117.

Emotional Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway

Crhistian Luis Bender, Xingxing Sun, Muhammad Farooq, Qian Yang, Caroline Davison, Matthieu Maroteaux, Yi-shuian Huang, Yoshihiro Ishikawa, Siqiong June Liu

J Neurosci. 2020 Apr 22; 40(17): 3374–3384. doi: 10.1523/JNEUROSCI.0013-19.2020

PMCID:: PMC7178911

Abstract Article PDF–4.6M

Select item 67580688.

Impaired D2 Dopamine Receptor Function in Mice Lacking Type 5 Adenylyl Cyclase

Ko-Woon Lee, Jang-Hee Hong, In Young Choi, Yongzhe Che, Ja-Kyeong Lee, Sung-Don Yang, Chang-Woo Song, Ho Sung Kang, Jae-Heun Lee, Jai Sung Noh, Hee-Sup Shin, Pyung-Lim Han

J Neurosci. 2002 Sep 15; 22(18): 7931–7940. doi: 10.1523/JNEUROSCI.22-18-07931.2002

PMCID:: PMC6758068

Abstract Article PDF–410K

Select item 66724409.

Molecular Characterization of the Ankle-Link Complex in Cochlear Hair Cells and Its Role in the Hair Bundle Functioning

Nicolas Michalski, Vincent Michel, Amel Bahloul, Gaëlle Lefèvre, Jérémie Barral, Hideshi Yagi, Sébastien Chardenoux, Dominique Weil, Pascal Martin, Jean-Pierre Hardelin, Makoto Sato, Christine Petit

J Neurosci. 2007 Jun 13; 27(24): 6478–6488. doi: 10.1523/JNEUROSCI.0342-07.2007

PMCID:: PMC6672440

Abstract Article PDF–1.0M

Select item 666867910.

Adenylyl cyclase 5–generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Arsalan U. Syed, Gopireddy R. Reddy, Debapriya Ghosh, Maria Paz Prada, Matthew A. Nystoriak, Stefano Morotti, Eleonora Grandi, Padmini Sirish, Nipavan Chiamvimonvat, Johannes W. Hell, Luis F. Santana, Yang K. Xiang, Madeline Nieves-Cintrón, Manuel F. Navedo

J Clin Invest. 2019 Aug 1; 129(8): 3140–3152. Published online 2019 Jul 2. doi: 10.1172/JCI124705

PMCID:: PMC6668679

Abstract Article PDF–7.1M

Select item 660840911.

Inhibition of Adenylyl Cyclase Type 5 Prevents l-DOPA-Induced Dyskinesia in an Animal Model of Parkinson's Disease

Hye-Yeon Park, Young-Mi Kang, Young Kang, Tae-Shin Park, Young-Kyoung Ryu, Jung-Hwan Hwang, Yong-Hoon Kim, Bong-Hyun Chung, Ki-Hoan Nam, Mee-Ree Kim, Chul-Ho Lee, Pyung-Lim Han, Kyoung-Shim Kim

J Neurosci. 2014 Aug 27; 34(35): 11744–11753. doi: 10.1523/JNEUROSCI.0864-14.2014

PMCID:: PMC6608409

Abstract Article PDF–2.2M

Select item 655698112.

Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6

Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H. Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert

PLoS One. 2019; 14(6): e0218110. Published online 2019 Jun 7. doi: 10.1371/journal.pone.0218110

PMCID:: PMC6556981

Abstract Article PDF–2.3M

Select item 631390013.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 610382014.

A Novel Adenylyl Cyclase Type 5 Inhibitor That Reduces Myocardial Infarct Size Even When Administered After Coronary Artery Reperfusion

Jie Zhang, Daniel Levy, Marko Oydanich, Claudio Bravo, Seonghun Yoon, Dorothy E. Vatner, Stephen F. Vatner

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 13–15. Published online 2018 May 22. doi: 10.1016/j.yjmcc.2018.05.014

PMCID:: PMC6103820

Abstract Article PDF–324K

Select item 591899315.

A molecular dynamics study of adenylyl cyclase: The impact of ATP and G-protein binding

Elisa Frezza, Juliette Martin, Richard Lavery

PLoS One. 2018; 13(4): e0196207. Published online 2018 Apr 25. doi: 10.1371/journal.pone.0196207

PMCID:: PMC5918993

Abstract Article PDF–8.1M

Select item 583329716.

Disruption of Adenylyl Cyclase Type 5 Mimics Exercise Training

John J. Guers, Jie Zhang, Sara C. Campbell, Marko Oydanich, Dorothy E. Vatner, Stephen F. Vatner

Basic Res Cardiol. Author manuscript; available in PMC 2018 Mar 8.

Published in final edited form as: Basic Res Cardiol. 2017 Sep 8; 112(6): 59. Published online 2017 Sep 8. doi: 10.1007/s00395-017-0648-8

PMCID:: PMC5833297

Abstract Article PDF–3.5M

Select item 579457217.

Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease

Qian Wang, Patricia Cobo-Stark, Vishal Patel, Stefan Somlo, Pyung-Lim Han, Peter Igarashi

Kidney Int. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Kidney Int. 2018 Feb; 93(2): 403–415. Published online 2017 Oct 14. doi: 10.1016/j.kint.2017.08.005

PMCID:: PMC5794572

Abstract Article PDF–2.5M

Select item 535066918.

Bitransgenesis with β₂‐Adrenergic Receptors or Adenylyl Cyclase Fails to Improve β₁‐Adrenergic Receptor Cardiomyopathy

Natalia Petrashevskaya, Brigitte R. Gaume, Kathryn A. Mihlbachler, Gerald W. Dorn II, Stephen B. Liggett

Clin Transl Sci. 2008 Dec; 1(3): 221–227. Published online 2008 Oct 24. doi: 10.1111/j.1752-8062.2008.00061.x

PMCID:: PMC5350669

Abstract Article PDF–558K

Select item 531649619.

Adenylyl Cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in Polycystic Liver Disease

Carlo Spirli, Valeria Mariotti, Ambra Villani, Luca Fabris, Romina Fiorotto, Mario Strazzabosco

J Hepatol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: J Hepatol. 2017 Mar; 66(3): 571–580. Published online 2016 Nov 5. doi: 10.1016/j.jhep.2016.10.032

PMCID:: PMC5316496

Abstract Article PDF–2.0M

Select item 484486320.

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: evidence for regulation of visceral smooth muscle genes by the Hedgehog target gene, cJun

Katherine Gurdziel, Kyle R. Vogt, Katherine D. Walton, Gary K. Schneider, Deborah L. Gumucio

Dev Dyn. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Dev Dyn. 2016 May; 245(5): 614–626. Published online 2016 Mar 17. doi: 10.1002/dvdy.24399

PMCID:: PMC4844863

Abstract Article PDF–2.1M

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