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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 108698002.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett

Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4

PMCID:: PMC10869800

Abstract Article PDF–9.3M

Select item 105658763.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103244734.

Expanding the Molecular Diversity of CIC-Rearranged Sarcomas with Novel and Very Rare Partners

Konstantinos Linos, Josephine K. Dermawan, Tejus Bale, Marc K. Rosenblum, Samuel Singer, William Tap, Mark A. Dickson, Jason L. Hornick, Cristina R. Antonescu

Mod Pathol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Mod Pathol. 2023 May; 36(5): 100103. Published online 2023 Jan 21. doi: 10.1016/j.modpat.2023.100103

PMCID:: PMC10324473

Abstract Article PDF–2.5M

Select item 98438855.

CIC reduces xCT/SLC7A11 expression and glutamate release in glioma

Jong-Whi Park, Omer Kilic, Minh Deo, Kevin Jimenez-Cowell, Engin Demirdizen, Hyunggee Kim, Şevin Turcan

Acta Neuropathol Commun. 2023; 11: 13. Published online 2023 Jan 16. doi: 10.1186/s40478-023-01507-y

PMCID:: PMC9843885

Abstract Article PDF–1.8M

Select item 97721156.

CIC missense variants contribute to susceptibility for spina bifida

Xiao Han, Xuanye Cao, Vanessa Aguiar-Pulido, Wei Yang, Menuka Karki, Paula Andrea Pimienta Ramirez, Robert M. Cabrera, Ying Linda Lin, Bogdan J. Wlodarczyk, Gary M. Shaw, M. Elizabeth Ross, Cuilian Zhang, Richard H. Finnell, Yunping Lei

Hum Mutat. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Hum Mutat. 2022 Dec; 43(12): 2021–2032. Published online 2022 Sep 12. doi: 10.1002/humu.24460

PMCID:: PMC9772115

Abstract Article PDF–1.9M

Select item 97696987.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 97080868.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 96742089.

Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer

Ji Won Kim, Cuyler Luck, Wei Wu, Rovingaile Kriska Ponce, Yone Kawe Lin, Nehal Gupta, Ross A. Okimoto

Cell Rep. Author manuscript; available in PMC 2022 Nov 18.

Published in final edited form as: Cell Rep. 2022 Oct 4; 41(1): 111443. doi: 10.1016/j.celrep.2022.111443

PMCID:: PMC9674208

Abstract Article PDF–1.5M

Select item 966833510.

The CIC-ERF co-deletion underlies fusion-independent activation of ETS family member, ETV1, to drive prostate cancer progression

Nehal Gupta, Hanbing Song, Wei Wu, Rovingaile K Ponce, Yone K Lin, Ji Won Kim, Eric J Small, Felix Y Feng, Franklin W Huang, Ross A Okimoto

eLife. 2022; 11: e77072. Published online 2022 Nov 16. doi: 10.7554/eLife.77072

PMCID:: PMC9668335

Abstract Article PDF–3.2M

Select item 954034511.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 930513712.

Integrative multi‐omic analysis reveals neurodevelopmental gene dysregulation in CIC‐knockout and IDH1‐mutant cells

Stephen D Lee, Jungeun Song, Veronique G LeBlanc, Marco A Marra

J Pathol. 2022 Mar; 256(3): 297–309. Published online 2021 Dec 22. doi: 10.1002/path.5835

PMCID:: PMC9305137

Abstract Article PDF–3.7M

Select item 926261413.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 901471114.

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach

Cell Rep. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030

PMCID:: PMC9014711

Abstract Article PDF–2.2M

Select item 882889515.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 876907216.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 876331717.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 845674818.

c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein

Severa Bunda, Pardeep Heir, Annie Si Cong Li, Yasin Mamatjan, Gelareh Zadeh, Kenneth Aldape

Mol Cancer Res. Author manuscript; available in PMC 2021 Sep 22.

Published in final edited form as: Mol Cancer Res. 2020 May; 18(5): 774–786. Published online 2020 Feb 6. doi: 10.1158/1541-7786.MCR-18-1370

PMCID:: PMC8456748

Abstract Article PDF–1.6M

Select item 843621519.

Imaging features and clinical course of undifferentiated round cell sarcomas with CIC-DUX4 and BCOR-CCNB3 translocations

Emily J Brady, Meera Hameed, William D. Tap, Sinchun Hwang

Skeletal Radiol. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Skeletal Radiol. 2021 Mar; 50(3): 521–529. Published online 2020 Aug 25. doi: 10.1007/s00256-020-03589-4

PMCID:: PMC8436215

Abstract Article PDF–582K

Select item 835399320.

Expanding the differential of superficial tumors with round cell morphology: report of three cases of CIC-rearranged sarcoma, a potentially under-recognized entity

Nolan Maloney, Stephen M. Smith, Sara B. Peters, Anna Batistatou, Zoi Evangelou, Paul W. Harms, May P. Chan, Cristina R. Antonescu, Konstantinos Linos

J Cutan Pathol. Author manuscript; available in PMC 2021 Aug 10.

Published in final edited form as: J Cutan Pathol. 2020 Jun; 47(6): 535–540. Published online 2020 Jan 10. doi: 10.1111/cup.13639

PMCID:: PMC8353993

Abstract Article PDF–3.7M

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