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Select item 110152231.

OMA1 competitively binds to HSPA9 to promote mitophagy and activate the cGAS–STING pathway to mediate GBM immune escape

Wen de Zhu, Jin Rao, Li hua Zhang, Ka ming Xue, Lin Li, Jun jun Li, Qian zhi Chen, Rong Fu

J Immunother Cancer. 2024; 12(4): e008718. Published online 2024 Apr 11. doi: 10.1136/jitc-2023-008718

Correction in:: J Immunother Cancer. 2024; 12(11): e008718corr1.

PMCID:: PMC11015223

Abstract Article PDF–18M

Select item 101022932.

Long Noncoding RNA PCGEM1 Facilitates Tumor Growth and Metastasis of Osteosarcoma by Sponging miR‐433‐3p and Targeting OMA1

Jun Li, Yuanjin Zhang, Farui Sun, Guofu Zhang, Xi‐an Pan, Qian Zhou

Orthop Surg. 2023 Apr; 15(4): 1060–1071. Published online 2023 Feb 13. doi: 10.1111/os.13648

PMCID:: PMC10102293

Abstract Article PDF–2.2M

Select item 88359643.

The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer

Meiyu Cheng, Huimei Yu, Qinghuan Kong, Bingrong Wang, Luyan Shen, Delu Dong, Liankun Sun

Int J Mol Sci. 2022 Feb; 23(3): 1320. Published online 2022 Jan 25. doi: 10.3390/ijms23031320

PMCID:: PMC8835964

Abstract Article PDF–5.6M

Select item 85253144.

Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer’s Disease.

Marcel V. Alavi

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2021 Nov; 1868(12): 119116. Published online 2021 Aug 13. doi: 10.1016/j.bbamcr.2021.119116

PMCID:: PMC8525314

Abstract Article PDF–1.0M

Select item 83830365.

Circular RNA OMA1 regulates the progression of breast cancer via modulation of the miR-1276/SIRT4 axis

Lingli Xu, Ke Xu, Lijun Xiang, Jiamei Yan

Mol Med Rep. 2021 Oct; 24(4): 728. Published online 2021 Aug 13. doi: 10.3892/mmr.2021.12367

PMCID:: PMC8383036

Abstract Article PDF–1.3M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77700617.

OMA1—an integral membrane protease?

Marcel V. Alavi

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2021 Feb; 1869(2): 140558. Published online 2020 Oct 29. doi: 10.1016/j.bbapap.2020.140558

PMCID:: PMC7770061

Abstract Article PDF–1.1M

Select item 77376128.

Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation

Daisuke Murata, Tatsuya Yamada, Takeshi Tokuyama, Kenta Arai, Pedro M Quirós, Carlos López‐Otín, Miho Iijima, Hiromi Sesaki

EMBO J. 2020 Dec 15; 39(24): e105074. Published online 2020 Nov 17. doi: 10.15252/embj.2020105074

PMCID:: PMC7737612

Abstract Article PDF–3.5M

Select item 71478329.

Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway

Xiaoyan Guo, Giovanni Aviles, Yi Liu, Ruilin Tian, Bret A. Unger, Yu-Hsiu T. Lin, Arun P. Wiita, Ke Xu, M. Almira Correia, Martin Kampmann

Nature. Author manuscript; available in PMC 2020 Sep 4.

Published in final edited form as: Nature. 2020 Mar; 579(7799): 427–432. Published online 2020 Mar 4. doi: 10.1038/s41586-020-2078-2

PMCID:: PMC7147832

Abstract Article PDF–3.1M

Select item 711671510.

A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol

Evelyn Fessler, Eva-Maria Eckl, Sabine Schmitt, Igor Alves Mancilla, Matthias F. Meyer-Bender, Monika Hanf, Julia Philippou-Massier, Stefan Krebs, Hans Zischka, Lucas T. Jae

Nature. Author manuscript; available in PMC 2021 Feb 9.

Published in final edited form as: Nature. 2020 Mar 1; 579(7799): 433–437. Published online 2020 Mar 4. doi: 10.1038/s41586-020-2076-4

PMCID:: PMC7116715

Abstract Article PDF–6.3M

Select item 679188211.

Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells

Amita Daverey, Roman M. Levytskyy, Kimberly M. Stanke, Martonio Ponte Viana, Samantha Swenson, Stephen L. Hayward, Madhusudhanan Narasimhan, Oleh Khalimonchuk, Srivatsan Kidambi

Sci Rep. 2019; 9: 14746. Published online 2019 Oct 14. doi: 10.1038/s41598-019-49327-2

PMCID:: PMC6791882

Abstract Article PDF–4.5M

Select item 594559912.

Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation

Fan Yang, Rongrong Wu, Zhi Jiang, Jinghai Chen, Jinliang Nan, Sheng’an Su, Na Zhang, Chen Wang, Jing Zhao, Cheng Ni, Yingchao Wang, Wangxing Hu, Zhiru Zeng, Keyang Zhu, Xianbao Liu, Xinyang Hu, Wei Zhu, Hong Yu, Jinyu Huang, Jian’an Wang

Cell Death Dis. 2018 May; 9(5): 556. Published online 2018 May 10. doi: 10.1038/s41419-018-0579-9

PMCID:: PMC5945599

Abstract Article PDF–4.1M

Select item 586483213.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 570387814.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Abstract Article PDF–3.7M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 478504716.

Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity During Stress

T. Kelly Rainbolt, Justine Lebeau, Cristina Puchades, R. Luke Wiseman

Cell Rep. Author manuscript; available in PMC 2016 Mar 9.

Published in final edited form as: Cell Rep. 2016 Mar 8; 14(9): 2041–2049. Published online 2016 Feb 25. doi: 10.1016/j.celrep.2016.02.011

PMCID:: PMC4785047

Abstract Article PDF–1.2M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 435553718.

C11orf83, a Mitochondrial Cardiolipin-Binding Protein Involved in bc₁ Complex Assembly and Supercomplex Stabilization

Marjorie Desmurs, Michelangelo Foti, Etienne Raemy, Frédéric Maxime Vaz, Jean-Claude Martinou, Amos Bairoch, Lydie Lane

Mol Cell Biol. 2015 Apr; 35(7): 1139–1156. Prepublished online 2015 Jan 20. Published online 2015 Mar 10. doi: 10.1128/MCB.01047-14

PMCID:: PMC4355537

Abstract Article PDF–3.6M

Select item 421008919.

Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage

Kuan Zhang, Huihui Li, Zhiyin Song

EMBO Rep. 2014 May; 15(5): 576–585. Published online 2014 Apr 9. doi: 10.1002/embr.201338240

PMCID:: PMC4210089

Abstract Article PDF–1.3M

Select item 420566320.

Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis

Xian Jiang, Hui Jiang, Zhirong Shen, Xiaodong Wang

Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41): 14782–14787. Published online 2014 Oct 1. doi: 10.1073/pnas.1417253111

PMCID:: PMC4205663

Abstract Article PDF–1.3M

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