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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109007102.

Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington’s disease

Ian D. Gaudet, Hongyuan Xu, Emily Gordon, Gianna A. Cannestro, Michael L. Lu, Jianning Wei

J Neuroinflammation. 2024; 21: 59. Published online 2024 Feb 28. doi: 10.1186/s12974-024-03038-2

PMCID:: PMC10900710

Abstract Article PDF–4.0M

Select item 107786483.

Integrated Amino Acids and Transcriptome Analysis Reveals Arginine Transporter SLC7A2 Is a Novel Regulator of Myogenic Differentiation

Tiane Huang, Jing Zhou, Benhui Wang, Xiang Wang, Wanli Xiao, Mengqi Yang, Yan Liu, Qiquan Wang, Yang Xiang, Xinqiang Lan

Int J Mol Sci. 2024 Jan; 25(1): 95. Published online 2023 Dec 20. doi: 10.3390/ijms25010095

PMCID:: PMC10778648

Abstract Article PDF–4.1M

Select item 97945544.

SLC3A2 and SLC7A2 Mediate the Exogenous Putrescine-Induced Adipocyte Differentiation

Jin Eom, Juhyun Choi, Sung-Suk Suh, Jong Bae Seo

Mol Cells. 2022 Dec 31; 45(12): 963–975. Published online 2022 Dec 21. doi: 10.14348/molcells.2022.0123

PMCID:: PMC9794554

Abstract Article PDF–1.4M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68428726.

Deficiency of cationic amino acid transporter-2 protects mice from hyperoxia-induced lung injury

Yi Jin, Yusen Liu, Leif D. Nelin

Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1; 316(4): L598–L607. Published online 2019 Jan 10. doi: 10.1152/ajplung.00223.2018

PMCID:: PMC6842872

Abstract Article

Select item 64119727.

Characterisation of genes differentially expressed in macrophages by virulent and attenuated Mycobacterium tuberculosisthrough RNA-Seq analysis

Junghwan Lee, Sung-Gwon Lee, Kee K. Kim, Yun-Ji Lim, Ji-Ae Choi, Soo-Na Cho, Chungoo Park, Chang-Hwa Song

Sci Rep. 2019; 9: 4027. Published online 2019 Mar 11. doi: 10.1038/s41598-019-40814-0

PMCID:: PMC6411972

Abstract Article PDF–1.9M

Select item 63773048.

Loss of Solute Carrier Family 7 Member 2 Exacerbates Inflammation-Associated Colon Tumorigenesis

Lori A. Coburn, Kshipra Singh, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Nicole T. Al-Greene, Dana M. Hardbower, Dina Polosukhina, Christopher S. Williams, Alberto G. Delgado, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson

Oncogene. Author manuscript; available in PMC 2019 Mar 10.

Published in final edited form as: Oncogene. 2019 Feb; 38(7): 1067–1079. Published online 2018 Sep 10. doi: 10.1038/s41388-018-0492-9

PMCID:: PMC6377304

Abstract Article PDF–2.5M

Select item 50811869.

The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria

Kshipra Singh, Nicole T. Al-Greene, Thomas G. Verriere, Lori A. Coburn, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Dana M. Hardbower, Alberto G. Delgado, M. Blanca Piazuelo, Bruce A. Vallance, Alain P. Gobert, Keith T. Wilson

PLoS Pathog. 2016 Oct; 12(10): e1005984. Published online 2016 Oct 26. doi: 10.1371/journal.ppat.1005984

PMCID:: PMC5081186

Abstract Article PDF–9.4M

Select item 465517010.

Expression of Cationic Amino Acid Transporter 2 (CAT2) Is Required for Myeloid Derived Suppressor Cell-Mediated Control of T Cell Immunity

Cansu Cimen Bozkus, Bennett D. Elzey, Scott A. Crist, Lesley G. Ellies, Timothy L. Ratliff

J Immunol. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: J Immunol. 2015 Dec 1; 195(11): 5237–5250. Published online 2015 Oct 21. doi: 10.4049/jimmunol.1500959

PMCID:: PMC4655170

Abstract Article PDF–636K

Select item 436591611.

Nitric Oxide Signaling Pathway in Duchenne Muscular Dystrophy Mice: Upregulation of L-arginine Transporters

Jayalakshmi Ramachandran, Joel S. Schneider, Pierre-Antoine Crassous, Ruifang Zheng, James P. Gonzalez, Lai-Hua Xie, Annie Beuve, Diego Fraidenraich, R. Daniel Peluffo

Biochem J. Author manuscript; available in PMC 2015 Mar 19.

Published in final edited form as: Biochem J. 2013 Jan 1; 449(1): 133–142. doi: 10.1042/BJ20120787

PMCID:: PMC4365916

Abstract Article PDF–1.3M

Select item 396495512.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 374286013.

Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response

Kshipra Singh, Lori A. Coburn, Daniel P. Barry, Mohammad Asim, Brooks P. Scull, Margaret M. Allaman, Nuruddeen D. Lewis, M. Kay Washington, Michael J. Rosen, Christopher S. Williams, Rupesh Chaturvedi, Keith T. Wilson

Am J Physiol Gastrointest Liver Physiol. 2013 Aug 1; 305(3): G225–G240. Published online 2013 May 23. doi: 10.1152/ajpgi.00091.2013

PMCID:: PMC3742860

Abstract Article

Select item 336208014.

L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution

Kshipra Singh, Lori A. Coburn, Daniel P. Barry, Jean-Luc Boucher, Rupesh Chaturvedi, Keith T. Wilson

Am J Physiol Gastrointest Liver Physiol. 2012 May 1; 302(9): G1061–G1073. Published online 2012 Feb 23. doi: 10.1152/ajpgi.00544.2011

PMCID:: PMC3362080

Abstract Article

Select item 323759015.

Cationic Amino Acid Transporter 2 Enhances Innate Immunity during Helicobacter pylori Infection

Daniel P. Barry, Mohammad Asim, Brooks P. Scull, M. Blanca Piazuelo, Thibaut de Sablet, Nuruddeen D. Lewis, Lori A. Coburn, Kshipra Singh, Lesley G. Ellies, Alain P. Gobert, Rupesh Chaturvedi, Keith T. Wilson

PLoS One. 2011; 6(12): e29046. Published online 2011 Dec 14. doi: 10.1371/journal.pone.0029046

PMCID:: PMC3237590

Abstract Article PDF–699K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 290644718.

The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis

Kathryn A Niese, Monica G Chiaramonte, Lesley G Ellies, Marc E Rothenberg, Nives Zimmermann

Respir Res. 2010; 11(1): 87. Published online 2010 Jun 24. doi: 10.1186/1465-9921-11-87

PMCID:: PMC2906447

Abstract Article PDF–7.0M

Select item 255627019.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 226542820.

Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

Robert W. Thompson, John T. Pesce, Thirumalai Ramalingam, Mark S. Wilson, Sandy White, Allen W. Cheever, Stacy M. Ricklefs, Stephen F. Porcella, Lili Li, Lesley G. Ellies, Thomas A. Wynn

PLoS Pathog. 2008 Mar; 4(3): e1000023. Published online 2008 Mar 14. doi: 10.1371/journal.ppat.1000023

PMCID:: PMC2265428

Abstract Article PDF–1.2M

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