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Items: 1 to 20 of 26

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
MAB21L1 modulates gene expression and DNA metabolic processes in the lens placode
Ryuichi Yamada, Akira Oguri, Katsunori Fujiki, Katsuhiko Shirahige, Yoshikazu Hirate, Masami Kanai-Azuma, Hirotaka Takezoe, Yoshihiro Akimoto, Naoki Takahashi, Yoshiakira Kanai
Dis Model Mech. 2021 Dec 1; 14(12): dmm049251. Published online 2021 Dec 23. doi: 10.1242/dmm.049251
PMCID:
PMC8713989
AbstractArticle
3.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
4.
Molecular Cloning and Functional Characterization of a New Modulatory Cyclic Nucleotide-Gated Channel Subunit from Mouse Retina
Andrea Gerstner, Xiangang Zong, Franz Hofmann, Martin Biel
J Neurosci. 2000 Feb 15; 20(4): 1324–1332. doi: 10.1523/JNEUROSCI.20-04-01324.2000
PMCID:
PMC6772363
AbstractArticlePDF–327K
5.
Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration
Hongwei Ma, Fan Yang, Michael R. Butler, Joshua Belcher, T. Michael Redmond, Andrew T. Placzek, Thomas S. Scanlan, Xi-Qin Ding
FASEB J. 2017 Aug; 31(8): 3425–3438. Published online 2017 Apr 20. doi: 10.1096/fj.201601166RR
PMCID:
PMC5503703
AbstractArticle
6.
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration
Fan Yang, Hongwei Ma, Joshua Belcher, Michael R. Butler, T. Michael Redmond, Sanford L. Boye, William W. Hauswirth, Xi-Qin Ding
FASEB J. 2016 Dec; 30(12): 4313–4325. Published online 2016 Sep 13. doi: 10.1096/fj.201600715R
PMCID:
PMC5102114
AbstractArticle
7.
The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility
Xi-Qin Ding, Arjun Thapa, Hongwei Ma, Jianhua Xu, Michael H. Elliott, Karla K. Rodgers, Marci L. Smith, Jin-Shan Wang, Steven J. Pittler, Vladimir J. Kefalov
J Biol Chem. 2016 Apr 15; 291(16): 8721–8734. Published online 2016 Feb 18. doi: 10.1074/jbc.M115.696138
PMCID:
PMC4861441
AbstractArticlePDF–3.0M
8.
Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3−/− Mouse Model of Achromatopsia
Dario Marangoni, Camasamudram Vijayasarathy, Ronald A. Bush, Lisa L. Wei, Rong Wen, Paul A. Sieving
Invest Ophthalmol Vis Sci. 2015 Oct; 56(11): 6810–6822. Published online 2015 Oct 22. doi: 10.1167/iovs.15-16866
PMCID:
PMC4627357
AbstractArticlePDF–1.3M
9.
Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3−/−/Nrl−/− mice, an all-cone model of CNGA3 achromatopsia
Wei Du, Ye Tao, Wen-Tao Deng, Ping Zhu, Jie Li, Xufeng Dai, Yuxin Zhang, Wei Shi, Xuan Liu, Vince A. Chiodo, Xi-Qin Ding, Chen Zhao, Stylianos Michalakis, Martin Biel, Zuoming Zhang, Jia Qu, William W. Hauswirth, Ji-jing Pang
Hum Mol Genet. 2015 Jul 1; 24(13): 3699–3707. Published online 2015 Apr 8. doi: 10.1093/hmg/ddv114
PMCID:
PMC4459390
AbstractArticlePDF–585K
10.
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration
Hongwei Ma, Arjun Thapa, Lynsie Morris, T. Michael Redmond, Wolfgang Baehr, Xi-Qin Ding
Proc Natl Acad Sci U S A. 2014 Mar 4; 111(9): 3602–3607. Published online 2014 Feb 18. doi: 10.1073/pnas.1317041111
PMCID:
PMC3948228
AbstractArticlePDF–2.3M
11.
Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study
Hongwei Ma, Arjun Thapa, Lynsie M. Morris, Stylianos Michalakis, Martin Biel, Mark Barton Frank, Melissa Bebak, Xi-Qin Ding
Hum Mol Genet. 2013 Oct 1; 22(19): 3906–3919. Published online 2013 Jun 4. doi: 10.1093/hmg/ddt245
PMCID:
PMC3766184
AbstractArticlePDF–1.0M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Biochemical Characterization of Cone Cyclic Nucleotide-gated (CNG) Channel Using the Infrared Fluorescence Detection System
Xi-Qin Ding, Alexander Matveev, Anil Singh, Naoka Komori, Hiroyuki Matsumoto
Adv Exp Med Biol. Author manuscript; available in PMC 2012 Jun 8.
Published in final edited form as: Adv Exp Med Biol. 2012; 723: 769–775. doi: 10.1007/978-1-4614-0631-0_98
PMCID:
PMC3370941
AbstractArticlePDF–951K
14.
Endoplasmic Reticulum Stress-associated Cone Photoreceptor Degeneration in Cyclic Nucleotide-gated Channel Deficiency
Arjun Thapa, Lynsie Morris, Jianhua Xu, Hongwei Ma, Stylianos Michalakis, Martin Biel, Xi-Qin Ding
J Biol Chem. 2012 May 25; 287(22): 18018–18029. Published online 2012 Apr 9. doi: 10.1074/jbc.M112.342220
PMCID:
PMC3365688
AbstractArticlePDF–3.3M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
RDS in Cones Does Not Interact with the Beta Subunit of the Cyclic Nucleotide Gated Channel
Shannon M. Conley, Xi-Qin Ding, Muna I. Naash
Adv Exp Med Biol. Author manuscript; available in PMC 2011 Aug 25.
Published in final edited form as: Adv Exp Med Biol. 2010; 664: 63–70. doi: 10.1007/978-1-4419-1399-9_8
PMCID:
PMC3161508
AbstractArticlePDF–997K
17.
Early-Onset, Slow Progression of Cone Photoreceptor Dysfunction and Degeneration in CNG Channel Subunit CNGB3 Deficiency
Jianhua Xu, Lynsie Morris, Steven J. Fliesler, David M. Sherry, Xi-Qin Ding
Invest Ophthalmol Vis Sci. 2011 May; 52(6): 3557–3566. Published online 2011 May 26. doi: 10.1167/iovs.10-6358
PMCID:
PMC3109041
AbstractArticlePDF–4.4M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1
Sabine Hüttl, Stylianos Michalakis, Mathias Seeliger, Dong-Gen Luo, Niyazi Acar, Heidi Geiger, Kristiane Hudl, Robert Mader, Silke Haverkamp, Markus Moser, Alexander Pfeifer, Andrea Gerstner, King-Wai Yau, Martin Biel
J Neurosci. 2005 Jan 5; 25(1): 130–138. doi: 10.1523/JNEUROSCI.3764-04.2005
PMCID:
PMC2885903
AbstractArticlePDF–682K
20.
The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry
Haining Zhong, Laurie L. Molday, Robert S. Molday, King-Wai Yau
Nature. Author manuscript; available in PMC 2010 May 27.
Published in final edited form as: Nature. 2002 Nov 14; 420(6912): 193–198. doi: 10.1038/nature01201
PMCID:
PMC2877395
AbstractArticlePDF–653K

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