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Items: 1 to 20 of 61

1.
Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors
Brit Neuhaus, Sebastian Bühren, Barbara Böck, Frauke Alves, Wolfgang F. Vogel, Friedemann Kiefer
Cell Mol Life Sci. 2011 Nov; 68(22): 3757–3770. Published online 2011 Apr 17. doi: 10.1007/s00018-011-0676-8
PMCID:
PMC11114838
AbstractArticlePDF–2.2M
2.
A discoidin domain receptor 1 knock-out mouse as a novel model for osteoarthritis of the temporomandibular joint
Boris Schminke, Hayat Muhammad, Christa Bode, Boguslawa Sadowski, Regina Gerter, Nikolaus Gersdorff, Ralf Bürgers, Efrat Monsonego-Ornan, Vicki Rosen, Nicolai Miosge
Cell Mol Life Sci. 2014 Mar; 71(6): 1081–1096. Published online 2013 Aug 4. doi: 10.1007/s00018-013-1436-8
PMCID:
PMC11113511
AbstractArticlePDF–1.9M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Euphorbia factor L1 suppresses breast cancer liver metastasis via DDR1-mediated immune infiltration
Dongjing Jiang, XiaoQin Gao, RuLan Tan, Xun Liu, Ye Zhu, Li Zhang
Aging (Albany NY) 2023 Sep 15; 15(17): 9217–9229. Published online 2023 Sep 14. doi: 10.18632/aging.205030
PMCID:
PMC10522367
AbstractArticlePDF–1.4M
5.
Evidence That DDR1 Promotes Oligodendrocyte Differentiation during Development and Myelin Repair after Injury
Ruyi Mei, Wanwan Qiu, Yingying Yang, Siyu Xu, Yueyu Rao, Qingxin Li, Yuhao Luo, Hao Huang, Aifen Yang, Huaping Tao, Mengsheng Qiu, Xiaofeng Zhao
Int J Mol Sci. 2023 Jun; 24(12): 10318. Published online 2023 Jun 19. doi: 10.3390/ijms241210318
PMCID:
PMC10299687
AbstractArticlePDF–12M
6.
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
Max Stevenson, Rency Varghese, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, R. Scott Turner, Charbel Moussa
J Neuroinflammation. 2023; 20: 116. Published online 2023 May 16. doi: 10.1186/s12974-023-02802-0
PMCID:
PMC10186647
AbstractArticlePDF–2.3M
7.
Opposing Roles of Hepatic Stellate Cell Subpopulations in Hepatocarcinogenesis
Aveline Filliol, Yoshinobu Saito, Ajay Nair, Dianne H. Dapito, Le-Xing Yu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Silvia Affo, Naoto Fujiwara, Hua Su, Qiuyan Sun, Thomas M Savage, John R Wilson-Kanamori, Jorge M Caviglia, LiKang Chin, Dongning Chen, Xiaobo Wang, Stefano Caruso, Jin Ku Kang, Amit Dipak Amin, Sebastian Wallace, Ross Dobie, Deqi Yin, Oscar M Rodriguez-Fiallos, Chuan Yin, Adam Mehal, Benjamin Izar, Richard A. Friedman, Rebecca G. Wells, Utpal B. Pajvani, Yujin Hoshida, Helen E. Remotti, Nicholas Arpaia, Jessica Zucman-Rossi, Michael Karin, Neil C Henderson, Ira Tabas, Robert F. Schwabe
Nature. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Nature. 2022 Oct; 610(7931): 356–365. Published online 2022 Oct 5. doi: 10.1038/s41586-022-05289-6
PMCID:
PMC9949942
AbstractArticlePDF–10M
8.
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
Hua Su, Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu, Avi Kumar, Jacopo Baglieri, Jeremy Siruno, Michelle Le, Yuhan Li, Stephen Dozier, Ajay Nair, Aveline Filliol, Nachanok Sinchai, Sara Brin Rosenthal, Jennifer Santini, Christian M. Metallo, Anthony Molina, Robert F. Schwabe, Andrew M. Lowy, David Brenner, Beicheng Sun, Michael Karin
Nature. 2022; 610(7931): 366–372. Published online 2022 Oct 5. doi: 10.1038/s41586-022-05169-z
Correction in:
Nature. 2023; 615(7953): E24.
PMCID:
PMC9588640
AbstractArticlePDF–58M
9.
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3
Corina M. Borza, Gema Bolas, Fabian Bock, Xiuqi Zhang, Favour C. Akabogu, Ming-Zhi Zhang, Mark de Caestecker, Min Yang, Haichun Yang, Ethan Lee, Leslie Gewin, Agnes B. Fogo, W. Hayes McDonald, Roy Zent, Ambra Pozzi
JCI Insight. 2022 Feb 8; 7(3): e150887. Published online 2022 Feb 8. doi: 10.1172/jci.insight.150887
PMCID:
PMC8855801
AbstractArticlePDF–12M
10.
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion
Xiujie Sun, Bogang Wu, Huai-Chin Chiang, Hui Deng, Xiaowen Zhang, Wei Xiong, Junquan Liu, Aaron M. Rozeboom, Brent T. Harris, Eline Blommaert, Antonio Gomez, Roderic Espin Garcia, Yufan Zhou, Payal Mitra, Madeleine Prevost, Deyi Zhang, Debarati Banik, Claudine Isaacs, Deborah Berry, Catherine Lai, Krysta Chaldekas, Patricia S. Latham, Christine A. Brantner, Anastas Popratiloff, Victor X. Jin, Ningyan Zhang, Yanfen Hu, Miguel Angel Pujana, Tyler J. Curiel, Zhiqiang An, Rong Li
Nature. Author manuscript; available in PMC 2022 Feb 12.
Published in final edited form as: Nature. 2021 Nov; 599(7886): 673–678. Published online 2021 Nov 3. doi: 10.1038/s41586-021-04057-2
PMCID:
PMC8839149
AbstractArticlePDF–5.9M
11.
DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis
Jenying Deng, Yaan Kang, Chien-Chia Cheng, Xinqun Li, Bingbing Dai, Matthew H. Katz, Taoyan Men, Michael P. Kim, Eugene A. Koay, Huocong Huang, Rolf A. Brekken, Jason B. Fleming
JCI Insight. 2021 Sep 8; 6(17): e146133. Published online 2021 Sep 8. doi: 10.1172/jci.insight.146133
PMCID:
PMC8492346
AbstractArticlePDF–29M
12.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
13.
Promotion of Cholangiocarcinoma Growth by Diverse Cancer-associated Fibroblast Subpopulations
Silvia Affo, Ajay Nair, Francesco Brundu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Michitaka Matsuda, LiKang Chin, Aveline Filliol, Wen Wen, Xinhua Song, Aubrianna Decker, Jeremy Worley, Jorge Matias Caviglia, Lexing Yu, Deqi Yin, Yoshinobu Saito, Thomas Savage, Rebecca G. Wells, Matthias Mack, Lars Zender, Nicholas Arpaia, Helen E. Remotti, Raul Rabadan, Peter Sims, Anne-Laure Leblond, Achim Weber, Marc-Oliver Riener, Brent R. Stockwell, Jellert Gaublomme, Josep M. Llovet, Raghu Kalluri, George K. Michalopoulos, Ekihiro Seki, Daniela Sia, Xin Chen, Andrea Califano, Robert F. Schwabe
Cancer Cell. Author manuscript; available in PMC 2022 Jun 14.
Published in final edited form as: Cancer Cell. 2021 Jun 14; 39(6): 866–882.e11. Published online 2021 Apr 29. doi: 10.1016/j.ccell.2021.03.012
Correction in:
Cancer Cell. 2021 Jun 14; 39(6): 883.
PMCID:
PMC8241235
AbstractArticlePDF–4.6M
14.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
15.
Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome
Jin-Ju Kim, Judith M. David, Sydney S. Wilbon, Javier V. Santos, Devang M. Patel, Anis Ahmad, Alla Mitrofanova, Xiaochen Liu, Shamroop K. Mallela, Gloria M. Ducasa, Mengyuan Ge, Alexis J. Sloan, Hassan Al-Ali, Marcia Boulina, Armando J. Mendez, Gabriel N. Contreras, Marco Prunotto, Anjum Sohail, Rafael Fridman, Jeffrey H. Miner, Sandra Merscher, Alessia Fornoni
EBioMedicine. 2021 Jan; 63: 103162. Published online 2020 Dec 16. doi: 10.1016/j.ebiom.2020.103162
PMCID:
PMC7750578
AbstractArticlePDF–4.1M
16.
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy
Hsin-Chaio Chou, Chung-Hwan Chen, Liang-Yin Chou, Tsung-Lin Cheng, Lin Kang, Shu-Chun Chuang, Yi-Shan Lin, Mei-Ling Ho, Yan-Hsiung Wang, Sung-Yen Lin, Chau-Zen Wang
Int J Mol Sci. 2020 Oct; 21(19): 6991. Published online 2020 Sep 23. doi: 10.3390/ijms21196991
PMCID:
PMC7583926
AbstractArticlePDF–3.2M
17.
Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38
Liang-Yin Chou, Chung-Hwan Chen, Shu-Chun Chuang, Tsung-Lin Cheng, Yi-Hsiung Lin, Hsin-Chiao Chou, Yin-Chih Fu, Yan-Hsiung Wang, Chau-Zen Wang
Int J Mol Sci. 2020 Oct; 21(19): 7210. Published online 2020 Sep 29. doi: 10.3390/ijms21197210
PMCID:
PMC7582985
AbstractArticlePDF–3.5M
18.
Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases
Alan J Fowler, Michaeline Hebron, Kaluvu Balaraman, Wangke Shi, Alexander A Missner, Jonathan D Greenzaid, Timothy L Chiu, Clementina Ullman, Ethan Weatherdon, Val Duka, Yasar Torres-Yaghi, Fernando L Pagan, Xiaoguang Liu, Habtom Ressom, Jaeil Ahn, Christian Wolf, Charbel Moussa
Hum Mol Genet. 2020 Sep 1; 29(17): 2882–2898. Published online 2020 Aug 8. doi: 10.1093/hmg/ddaa177
Correction in:
Hum Mol Genet. 2021 Jul 1; 30(13): 1271–1272.
PMCID:
PMC7566445
AbstractArticlePDF–1.7M
19.
Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma
Jeanine M. Ruggeri, Janusz Franco-Barraza, Anjum Sohail, Yaqing Zhang, Daniel Long, Marina Pasca di Magliano, Edna Cukierman, Rafael Fridman, Howard C. Crawford
Am J Pathol. 2020 Aug; 190(8): 1735–1751. doi: 10.1016/j.ajpath.2020.03.020
PMCID:
PMC7416078
AbstractArticlePDF–12M
20.
MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling
Nuno M. Coelho, Andrew Wang, Petar Petrovic, Yongqiang Wang, Wilson Lee, Christopher A. McCulloch
Cells. 2020 Jul; 9(7): 1672. Published online 2020 Jul 11. doi: 10.3390/cells9071672
PMCID:
PMC7407560
AbstractArticlePDF–9.8M

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