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Items: 1 to 20 of 95

1.
Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow
Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan
Nat Commun. 2024; 15: 3769. Published online 2024 May 4. doi: 10.1038/s41467-024-48255-8
PMCID:
PMC11069533
AbstractArticlePDF–41M
2.
Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression
Sofie J. Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M.F. Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher
Mol Metab. 2024 Jun; 84: 101938. Published online 2024 Apr 15. doi: 10.1016/j.molmet.2024.101938
PMCID:
PMC11059514
AbstractArticlePDF–3.7M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice
Hui Xia, Catherine R. Dufour, Younes Medkour, Charlotte Scholtes, Yonghong Chen, Christina Guluzian, Wafa B’chir, Vincent Giguère
Nat Commun. 2023; 14: 6982. Published online 2023 Nov 1. doi: 10.1038/s41467-023-42785-3
PMCID:
PMC10620240
AbstractArticlePDF–3.5M
5.
ERRα fosters running endurance by driving myofiber aerobic transformation and fuel efficiency
Hui Xia, Charlotte Scholtes, Catherine R. Dufour, Christina Guluzian, Vincent Giguère
Mol Metab. 2023 Dec; 78: 101814. Published online 2023 Oct 5. doi: 10.1016/j.molmet.2023.101814
PMCID:
PMC10590867
AbstractArticlePDF–4.2M
6.
Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation
Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij
Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2
PMCID:
PMC10404286
AbstractArticlePDF–3.4M
7.
PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes
Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jennifer L. Estall, Jorge L. Ruas, Pasi Tavi
Cells. 2022 Oct; 11(19): 2944. Published online 2022 Sep 20. doi: 10.3390/cells11192944
PMCID:
PMC9564192
AbstractArticlePDF–3.2M
8.
Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
Catherine R. Dufour, Hui Xia, Wafa B’chir, Marie-Claude Perry, Uros Kuzmanov, Anastasiia Gainullina, Kurt Dejgaard, Charlotte Scholtes, Carlo Ouellet, Dongmei Zuo, Virginie Sanguin-Gendreau, Christina Guluzian, Harvey W. Smith, William J. Muller, Etienne Audet-Walsh, Alexey A. Sergushichev, Andrew Emili, Vincent Giguère
Commun Biol. 2022; 5: 955. Published online 2022 Sep 12. doi: 10.1038/s42003-022-03942-4
PMCID:
PMC9467976
AbstractArticlePDF–4.6M
9.
Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCDcl1 Cells
Anna Keppner, Darko Maric, Ilaria Maria Christina Orlando, Laurent Falquet, Edith Hummler, David Hoogewijs
Int J Mol Sci. 2022 Jul; 23(13): 7262. Published online 2022 Jun 30. doi: 10.3390/ijms23137262
PMCID:
PMC9267015
AbstractArticlePDF–3.0M
10.
The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation
Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo, Lingzhi Li, Tomohito Doke, Shizheng Huang, Juanjuan Zhao, Hyun Mi Kang, Rojesh Shrestra, Michael S. Balzer, Shatakshee Chatterjee, Patricia Prado, Seung Yub Han, Hongbo Liu, Xin Sheng, Pieterjan Dierickx, Kirill Batmanov, Juan P. Romero, Felipe Prósper, Mingyao Li, Liming Pei, Junhyong Kim, Nuria Montserrat, Katalin Susztak
Cell Metab. Author manuscript; available in PMC 2022 Jul 6.
Published in final edited form as: Cell Metab. 2021 Feb 2; 33(2): 379–394.e8. Published online 2020 Dec 9. doi: 10.1016/j.cmet.2020.11.011
PMCID:
PMC9259369
AbstractArticlePDF–3.1M
11.
Estrogen-related receptor alpha (ERRα) is required for PGC-1α-dependent gene expression in the mouse brain
LJ McMeekin, KL Joyce, LM Jenkins, BM Bohannon, KD Patel, AS Bohannon, A Patel, SN Fox, MS Simmons, JJ Day, A Kralli, DK Crossman, RM Cowell
Neuroscience. Author manuscript; available in PMC 2022 Dec 15.
Published in final edited form as: Neuroscience. 2021 Dec 15; 479: 70–90. Published online 2021 Oct 11. doi: 10.1016/j.neuroscience.2021.10.007
Correction in:
Neuroscience. 2022 Jun 15; 493: 119.
PMCID:
PMC9124582
AbstractArticlePDF–2.3M
12.
Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis
Hui Xia, Charlotte Scholtes, Catherine R. Dufour, Carlo Ouellet, Majid Ghahremani, Vincent Giguère
Nat Commun. 2022; 13: 2105. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29722-6
PMCID:
PMC9019090
AbstractArticlePDF–2.8M
13.
LOSS OF ESTROGEN-RELATED RECEPTOR ALPHA DISRUPTS VENTRAL-STRIATAL SYNAPTIC FUNCTION IN FEMALE MICE
HÉCTOR DE JESÚS-CORTÉS, YUAN LU, RACHEL M. ANDERSON, MICHAEL Z. KHAN, VARUN NATH, LATISHA MCDANIEL, MICHAEL LUTTER, JASON J. RADLEY, ANDREW A. PIEPER, HUXING CUI
Neuroscience. Author manuscript; available in PMC 2022 Mar 11.
Published in final edited form as: Neuroscience. 2016 Aug 4; 329: 66–73. Published online 2016 May 4. doi: 10.1016/j.neuroscience.2016.04.054
PMCID:
PMC8916097
AbstractArticlePDF–1.2M
14.
ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota
Sup Kim, June-Young Lee, Seul Gi Shin, Jin Kyung Kim, Prashanta Silwal, Young Jae Kim, Na-Ri Shin, Pil Soo Kim, Minho Won, Sang-Hee Lee, Soo Yeon Kim, Miwa Sasai, Masahiro Yamamoto, Jin-Man Kim, Jin-Woo Bae, Eun-Kyeong Jo
Autophagy. 2021; 17(10): 2856–2875. Published online 2020 Dec 15. doi: 10.1080/15548627.2020.1847460
PMCID:
PMC8525935
AbstractArticlePDF–11M
15.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
16.
Estrogen-related receptor alpha (ERRα) is a key regulator of intestinal homeostasis and protects against colitis
Allan Tran, Charlotte Scholtes, Mario Songane, Claudia Champagne, Luc Galarneau, Marie-Pier Levasseur, Nassima Fodil, Catherine Rosa Dufour, Vincent Giguère, Maya Saleh
Sci Rep. 2021; 11: 15073. Published online 2021 Jul 23. doi: 10.1038/s41598-021-94499-5
PMCID:
PMC8302669
AbstractArticlePDF–6.9M
17.
Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis
Chien-yu Chen, Yang Li, Ni Zeng, Lina He, Xinwen Zhang, Taojian Tu, Qi Tang, Mario Alba, Sabrina Mir, Eileen X. Stiles, Handan Hong, Enrique Cadenas, Andrew A. Stolz, Gang Li, Bangyan L. Stiles
Am J Pathol. 2021 Jul; 191(7): 1240–1254. doi: 10.1016/j.ajpath.2021.04.007
PMCID:
PMC8261472
AbstractArticlePDF–2.3M
18.
Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver
Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova
Sci Rep. 2021; 11: 13766. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93216-6
Correction in:
Sci Rep. 2021; 11: 22975.
PMCID:
PMC8253761
AbstractArticlePDF–7.9M
19.
Perm1 promotes cardiomyocyte mitochondrial biogenesis and protects against hypoxia/reoxygenation-induced damage in mice
Yoshitake Cho, Shizuko Tachibana, Kayla Lam, Yoh Arita, Shamim Khosrowjerdi, Oliver Zhang, Alex Liang, Ruixia Li, Aleksander Andreyev, Anne N. Murphy, Robert S. Ross
J Biol Chem. 2021 Jul; 297(1): 100825. Published online 2021 May 23. doi: 10.1016/j.jbc.2021.100825
Correction in:
J Biol Chem. 2021 Sep; 297(3): 101121.
PMCID:
PMC8214196
AbstractArticlePDF–3.3M
20.
Down-regulation of estrogen-related receptor alpha (ERRα) inhibits gastric cancer cell migration and invasion in vitro and in vivo
Yuejiao Zhong, Kang He, Lin Shi, Lingxiang Chen, Bin Zhou, Rong Ma, Hui Yu, Jia Zhang, You Shuai, Yan Fei, Jianwei Lu
Aging (Albany NY) 2021 Feb 28; 13(4): 5845–5857. Published online 2021 Feb 11. doi: 10.18632/aging.202508
PMCID:
PMC7950300
AbstractArticlePDF–1.5M

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