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Select item 111725461.

Modified mRNA-Mediated CCN5 Gene Transfer Ameliorates Cardiac Dysfunction and Fibrosis without Adverse Structural Remodeling

Min Ho Song, Jimeen Yoo, Do-A Kwon, Elena Chepurko, Sunghye Cho, Anthony Fargnoli, Roger J. Hajjar, Woo Jin Park, Lior Zangi, Dongtak Jeong

Int J Mol Sci. 2024 Jun; 25(11): 6262. Published online 2024 Jun 6. doi: 10.3390/ijms25116262

PMCID:: PMC11172546

Abstract Article PDF–8.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 75797203.

The matricellular protein CCN5 prevents adverse atrial structural and electrical remodelling

Min‐Ah Lee, Nour Raad, Min Ho Song, Jimeen Yoo, Miyoung Lee, Seung Pil Jang, Tae Hwan Kwak, Hyun Kook, Eun‐Kyoung Choi, Tae‐Joon Cha, Roger J. Hajjar, Dongtak Jeong, Woo Jin Park

J Cell Mol Med. 2020 Oct; 24(20): 11768–11778. Published online 2020 Sep 4. doi: 10.1111/jcmm.15789

PMCID:: PMC7579720

Abstract Article PDF–1.1M

Select item 69566204.

Cooperative Regulation of Chondrocyte Differentiation by CCN2 and CCN3 Shown by a Comprehensive Analysis of the CCN Family Proteins in Cartilage

Harumi Kawaki, Satoshi Kubota, Akiko Suzuki, Noureddine Lazar, Tomohiro Yamada, Tatsushi Matsumura, Toshihiro Ohgawara, Takeyasu Maeda, Bernard Perbal, Karen M Lyons, Masaharu Takigawa

J Bone Miner Res. 2008 Nov; 23(11): 1751–1764. Published online 2008 Jun 30. doi: 10.1359/jbmr.080615

PMCID:: PMC6956620

Abstract Article PDF–5.8M

Select item 63016925.

The matricellular protein CCN5 inhibits fibrotic deformation of retinal pigment epithelium

Aeri Yoon, Sora Im, Juyeon Lee, Daeho Park, Dong Hyun Jo, Jin Hyoung Kim, Jeong Hun Kim, Woo Jin Park

PLoS One. 2018; 13(12): e0208897. Published online 2018 Dec 20. doi: 10.1371/journal.pone.0208897

PMCID:: PMC6301692

Abstract Article PDF–2.9M

Select item 62615676.

CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes

Jihwa Kim, Sanghyun Joo, Gwang Hyeon Eom, Seung Hoon Lee, Min-Ah Lee, Miyoung Lee, Ki Woo Kim, Do Han Kim, Hyun Kook, Tae Hwan Kwak, Woo Jin Park

PLoS One. 2018; 13(11): e0207228. Published online 2018 Nov 28. doi: 10.1371/journal.pone.0207228

PMCID:: PMC6261567

Abstract Article PDF–4.6M

Select item 58422097.

Characterization of bone morphology in CCN5/WISP5 knockout mice

Jie Jiang, Gexin Zhao, Karen M. Lyons

J Cell Commun Signal. 2018 Mar; 12(1): 265–270. Published online 2018 Feb 2. doi: 10.1007/s12079-018-0457-3

Correction in:: J Cell Commun Signal. 2018 Mar; 12(1): 271.

PMCID:: PMC5842209

Abstract Article PDF–2.5M

Select item 55693338.

CCN5/WISP-2 restores ER-∝ in normal and neoplastic breast cells and sensitizes triple negative breast cancer cells to tamoxifen

S Sarkar, A Ghosh, S Banerjee, G Maity, A Das, M A Larson, V Gupta, I Haque, O Tawfik, S K Banerjee

Oncogenesis. 2017 May; 6(5): e340. Published online 2017 May 22. doi: 10.1038/oncsis.2017.43

PMCID:: PMC5569333

Abstract Article PDF–4.0M

Select item 53274869.

Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

John R. Grünberg, Jenny M. Hoffmann, Shahram Hedjazifar, Annika Nerstedt, Lachmi Jenndahl, Johannes Elvin, John Castellot, Lan Wei, Sofia Movérare-Skrtic, Claes Ohlsson, Louise Mannerås Holm, Fredrik Bäckhed, Ismail Syed, Fatima Bosch, Alan Saghatelian, Barbara B. Kahn, Ann Hammarstedt, Ulf Smith

Sci Rep. 2017; 7: 43515. Published online 2017 Feb 27. doi: 10.1038/srep43515

PMCID:: PMC5327486

Abstract Article PDF–2.7M

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 497021311.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 479350112.

Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate

Aimin Li, Shudong Ma, Susan M. Smith, Matt K. Lee, Ashley Fischer, Zea Borok, Saverio Bellusci, Changgong Li, Parviz Minoo

BMC Biol. 2016; 14: 19. Published online 2016 Mar 16. doi: 10.1186/s12915-016-0242-9

PMCID:: PMC4793501

Abstract Article PDF–2.1M

Select item 396495513.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 394535114.

The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT

John R. Grünberg, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith

J Biol Chem. 2014 Mar 7; 289(10): 6899–6907. Published online 2014 Jan 22. doi: 10.1074/jbc.M113.511964

PMCID:: PMC3945351

Abstract Article PDF–1.8M

Select item 357491315.

WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4

Ann Hammarstedt, Shahram Hedjazifar, Lachmi Jenndahl, Silvia Gogg, John Grünberg, Birgit Gustafson, Eva Klimcakova, Vladimir Stich, Dominique Langin, Markku Laakso, Ulf Smith

Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7): 2563–2568. Published online 2013 Jan 28. doi: 10.1073/pnas.1211255110

PMCID:: PMC3574913

Abstract Article PDF–1.0M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 349789517.

CCN5 Expression in mammals. III. Early embryonic mouse development

Ronald B. Myers, Kibibi Rwayitare, Lauren Richey, Janis Lem, John J. Castellot, Jr.

J Cell Commun Signal. 2012 Dec; 6(4): 217–223. Published online 2012 Aug 28. doi: 10.1007/s12079-012-0176-0

PMCID:: PMC3497895

Abstract Article PDF–451K

Select item 331200118.

PGE₂ through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth

Artiom Gruzdev, MyTrang Nguyen, Martina Kovarova, Beverly H. Koller

Prostaglandins Other Lipid Mediat. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Prostaglandins Other Lipid Mediat. 2012 Mar; 97(0): 109–119. Published online 2012 Feb 11. doi: 10.1016/j.prostaglandins.2012.02.001

PMCID:: PMC3312001

Abstract Article PDF–3.2M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 293710120.

O-Fucosylation of Thrombospondin Type 1 Repeats Restricts Epithelial to Mesenchymal Transition (EMT) and Maintains Epiblast Pluripotency During Mouse Gastrulation

Jianguang Du, Hideyuki Takeuchi, Christina Leonhard-Melief, Kenneth R. Shroyer, Malgosia Dlugosz, Robert S. Haltiwanger, Bernadette C. Holdener

Dev Biol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Dev Biol. 2010 Oct 1; 346(1): 25–38. Published online 2010 Jul 14. doi: 10.1016/j.ydbio.2010.07.008

PMCID:: PMC2937101

Abstract Article PDF–3.9M

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