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Select item 102682401.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 97127592.

Jian Zhang, Jing Chen, Yufei Lu, Yan Yang, Weize Chen, Bo Shen, Jiachang Hu, Ping Jia, Sujuan Xu, Yiqin Shi, Yichun Ning, Jialin Wang, Yi Fang, Shuan Zhao, Yang Li, Yan Dai, Xiaoyan Zhang, Meng Xiang, Yang Tian, Zhichao Liu, Nana Song, Xiaoqiang Ding

iScience. 2022 Dec 22; 25(12): 105620. Published online 2022 Nov 17. doi: 10.1016/j.isci.2022.105620

PMCID:: PMC9712759

Abstract Article PDF–11M

Select item 86285783.

Structural basis for pH-gating of the two-pore domain K⁺ channel TASK2

Baobin Li, Robert A. Rietmeijer, Stephen G. Brohawn

Nature. Author manuscript; available in PMC 2021 Nov 29.

Published in final edited form as: Nature. 2020 Oct; 586(7829): 457–462. Published online 2020 Sep 30. doi: 10.1038/s41586-020-2770-2

PMCID:: PMC8628578

Abstract Article PDF–4.2M

Select item 69814744.

Possible Contribution of Inflammation-Associated Hypoxia to Increased K_2P5.1 K⁺ Channel Expression in CD4⁺ T Cells of the Mouse Model for Inflammatory Bowel Disease

Kyoko Endo, Hiroaki Kito, Ryo Tanaka, Junko Kajikuri, Satoshi Tanaka, Elghareeb E. Elboray, Takayoshi Suzuki, Susumu Ohya

Int J Mol Sci. 2020 Jan; 21(1): 38. Published online 2019 Dec 19. doi: 10.3390/ijms21010038

PMCID:: PMC6981474

Abstract Article PDF–4.3M

Select item 57925695.

K_2P TASK‐2 and KCNQ1–KCNE3 K⁺ channels are major players contributing to intestinal anion and fluid secretion

Francisca Julio‐Kalajzić, Sandra Villanueva, Johanna Burgos, Margarita Ojeda, L. Pablo Cid, Thomas J. Jentsch, Francisco V. Sepúlveda

J Physiol. 2018 Feb 1; 596(3): 393–407. Published online 2017 Dec 18. doi: 10.1113/JP275178

PMCID:: PMC5792569

Abstract Article PDF–973K

Select item 55262116.

Identification of potassium and chloride channels in eccrine sweat glands

Chang-Yi Cui, Jian Sima, Mingzhu Yin, Marc Michel, Makoto Kunisada, David Schlessinger

J Dermatol Sci. Author manuscript; available in PMC 2017 Jul 25.

Published in final edited form as: J Dermatol Sci. 2016 Feb; 81(2): 129–131. Published online 2015 Nov 10. doi: 10.1016/j.jdermsci.2015.11.001

PMCID:: PMC5526211

Article PDF–517K

Select item 53718247.

Phosphatidylinositol (4,5)-bisphosphate dynamically regulates the K_2P background K⁺ channel TASK-2

María Isabel Niemeyer, L. Pablo Cid, Marc Paulais, Jacques Teulon, Francisco V. Sepúlveda

Sci Rep. 2017; 7: 45407. Published online 2017 Mar 30. doi: 10.1038/srep45407

PMCID:: PMC5371824

Abstract Article PDF–2.3M

Select item 51712298.

Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

Natasha N. Kumar, Ana Velic, Jorge Soliz, Yingtang Shi, Keyong Li, Sheng Wang, Janelle L. Weaver, Josh Sen, Stephen B.G. Abbott, Roman M. Lazarenko, Marie-Gabrielle Ludwig, Edward Perez-Reyes, Nilufar Mohebbi, Carla Bettoni, Max Gassmann, Thomas Suply, Klaus Seuwen, Patrice G. Guyenet, Carsten A. Wagner, Douglas A. Bayliss

Science. Author manuscript; available in PMC 2016 Dec 20.

Published in final edited form as: Science. 2015 Jun 12; 348(6240): 1255–1260. Published online 2015 Jun 11. doi: 10.1126/science.aaa0922

PMCID:: PMC5171229

Abstract Article PDF–1.1M

Select item 46599379.

KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing

Yves Cazals, Michelle Bévengut, Sébastien Zanella, Frédéric Brocard, Jacques Barhanin, Christian Gestreau

Nat Commun. 2015; 6: 8780. Published online 2015 Nov 9. doi: 10.1038/ncomms9780

PMCID:: PMC4659937

Abstract Article PDF–2.1M

Select item 462141810.

Pathophysiological significance of the two-pore domain K⁺ channel K_2P5.1 in splenic CD4⁺CD25⁻ T cell subset from a chemically-induced murine inflammatory bowel disease model

Sawa Nakakura, Miki Matsui, Aya Sato, Mizuki Ishii, Kyoko Endo, Sayaka Muragishi, Miki Murase, Hiroaki Kito, Hiroki Niguma, Natsumi Kurokawa, Masanori Fujii, Masatake Araki, Kimi Araki, Susumu Ohya

Front Physiol. 2015; 6: 299. Published online 2015 Oct 27. doi: 10.3389/fphys.2015.00299

PMCID:: PMC4621418

Abstract Article PDF–2.6M

Select item 458117511.

Murine K_2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K_2P3.1- and K_V1.3-Dependent Mechanisms

Stefan Bittner, Nicole Bobak, Majella-Sophie Hofmann, Michael K. Schuhmann, Tobias Ruck, Kerstin Göbel, Wolfgang Brück, Heinz Wiendl, Sven G. Meuth

Int J Mol Sci. 2015 Aug; 16(8): 16880–16896. Published online 2015 Jul 24. doi: 10.3390/ijms160816880

PMCID:: PMC4581175

Abstract Article PDF–4.2M

Select item 379244812.

TASK-2 Channels Contribute to pH Sensitivity of Retrotrapezoid Nucleus Chemoreceptor Neurons

Sheng Wang, Najate Benamer, Sébastien Zanella, Natasha N. Kumar, Yingtang Shi, Michelle Bévengut, David Penton, Patrice G. Guyenet, Florian Lesage, Christian Gestreau, Jacques Barhanin, Douglas A. Bayliss

J Neurosci. 2013 Oct 9; 33(41): 16033–16044. doi: 10.1523/JNEUROSCI.2451-13.2013

PMCID:: PMC3792448

Abstract Article PDF–2.2M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 320029314.

NBCe1 Mediates the Acute Stimulation of Astrocytic Glycolysis by Extracellular K⁺

Iván Ruminot, Robin Gutiérrez, Gaspar Peña-Münzenmayer, Carolina Añazco, Tamara Sotelo-Hitschfeld, Rodrigo Lerchundi, María Isabel Niemeyer, Gary E. Shull, L. Felipe Barros

J Neurosci. 2011 Oct 5; 31(40): 14264–14271. doi: 10.1523/JNEUROSCI.2310-11.2011

PMCID:: PMC3200293

Abstract Article PDF–2.1M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302680716.

Gating of a pH-Sensitive K_2P Potassium Channel by an Electrostatic Effect of Basic Sensor Residues on the Selectivity Filter

Leandro Zúñiga, Valeria Márquez, Fernando D. González-Nilo, Christophe Chipot, L. Pablo Cid, Francisco V. Sepúlveda, María Isabel Niemeyer

PLoS One. 2011; 6(1): e16141. Published online 2011 Jan 25. doi: 10.1371/journal.pone.0016141

PMCID:: PMC3026807

Abstract Article PDF–477K

Select item 287801917.

Separate Gating Mechanisms Mediate the Regulation of K_2P Potassium Channel TASK-2 by Intra- and Extracellular pH

María Isabel Niemeyer, L. Pablo Cid, Gaspar Peña-Münzenmayer, Francisco V. Sepúlveda

J Biol Chem. 2010 May 28; 285(22): 16467–16475. Published online 2010 Mar 29. doi: 10.1074/jbc.M110.107060

PMCID:: PMC2878019

Abstract Article PDF–1.4M

Select item 283667018.

Task2 potassium channels set central respiratory CO₂ and O₂ sensitivity

Christian Gestreau, Dirk Heitzmann, Joerg Thomas, Véronique Dubreuil, Sascha Bandulik, Markus Reichold, Saïd Bendahhou, Patricia Pierson, Christina Sterner, Julie Peyronnet-Roux, Chérif Benfriha, Ines Tegtmeier, Hannah Ehnes, Michael Georgieff, Florian Lesage, Jean-Francois Brunet, Christo Goridis, Richard Warth, Jacques Barhanin

Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5): 2325–2330. Published online 2010 Jan 19. doi: 10.1073/pnas.0910059107

PMCID:: PMC2836670

Abstract Article PDF–731K

Select item 255627019.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 222954520.

Role of TASK2 Potassium Channels Regarding Volume Regulation in Primary Cultures of Mouse Proximal Tubules

Herve Barriere, Radia Belfodil, Isabelle Rubera, Michel Tauc, Florian Lesage, Chantal Poujeol, Nicolas Guy, Jacques Barhanin, Philippe Poujeol

J Gen Physiol. 2003 Aug; 122(2): 177–190. doi: 10.1085/jgp.200308820

PMCID:: PMC2229545

Abstract Article PDF–1.0M

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