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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108971412.

Control of NAD⁺ homeostasis by autophagic flux modulates mitochondrial and cardiac function

Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel AJ Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel

EMBO J. 2024 Feb; 43(3): 362–390. Published online 2024 Jan 11. doi: 10.1038/s44318-023-00009-w

PMCID:: PMC10897141

Abstract Article PDF–4.3M

Select item 104039613.

Autophagy Plays a Crucial Role in Ameloblast Differentiation

C. Iwaya, A. Suzuki, J. Shim, C. G. Ambrose, J. Iwata

J Dent Res. 2023 Aug; 102(9): 1047–1057. Published online 2023 May 30. doi: 10.1177/00220345231169220

PMCID:: PMC10403961

Abstract Article PDF–4.5M

Select item 102085674.

Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis

Giovanni Quarato, Luigi Mari, Nicholas J. Barrows, Mao Yang, Sebastian Ruehl, Mark J. Chen, Cliff S. Guy, Jonathan Low, Taosheng Chen, Douglas R. Green

Sci Adv. 2023 May; 9(21): eadg8156. Published online 2023 May 24. doi: 10.1126/sciadv.adg8156

PMCID:: PMC10208567

Abstract Article PDF–1.7M

Select item 95204535.

Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging

Kun Liu, Xing Li, Zheng Li, Jiani Cao, Xiaoyan Li, Youqing Xu, Lei Liu, Tongbiao Zhao

Front Cell Dev Biol. 2022; 10: 910464. Published online 2022 Sep 15. doi: 10.3389/fcell.2022.910464

PMCID:: PMC9520453

Abstract Article PDF–1.9M

Select item 90156996.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 90145597.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 80591388.

Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors

Diana L. Bonilla, Abhisek Bhattacharya, Youbao Sha, Yi Xu, Qian Xiang, Arshad Kan, Chinnaswamy Jagannath, Masaaki Komatsu, N. Tony Eissa

Immunity. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Immunity. 2013 Sep 19; 39(3): 537–547. Published online 2013 Sep 12. doi: 10.1016/j.immuni.2013.08.026

PMCID:: PMC8059138

Abstract Article PDF–1.9M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 741599110.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 680293911.

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Jinjin Cai, Karla M. Pires, Maroua Ferhat, Bhagirath Chaurasia, Ma´rcio A. Buffolo, Rana Smalling, Ashot Sargsyan, Donald L. Atkinson, Scott A. Summers, Timothy E. Graham, Sihem Boudina

Cell Rep. Author manuscript; available in PMC 2019 Oct 21.

Published in final edited form as: Cell Rep. 2018 Nov 13; 25(7): 1708–1717.e5. doi: 10.1016/j.celrep.2018.10.040

PMCID:: PMC6802939

Abstract Article PDF–2.1M

Select item 577433312.

Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity

Houjun Xia, Wei Wang, Joel Crespo, Ilona Kryczek, Wei Li, Shuang Wei, Zhaoqun Bian, Tomasz Maj, Mingxiao He, Rebecca J. Liu, Youwen He, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Weiping Zou

Sci Immunol. Author manuscript; available in PMC 2018 Jan 19.

Published in final edited form as: Sci Immunol. 2017 Nov 17; 2(17): eaan4631. doi: 10.1126/sciimmunol.aan4631

PMCID:: PMC5774333

Abstract Article PDF–3.6M

Select item 575883013.

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy

Karen Frudd, Thomas Burgoyne, Joseph Robert Burgoyne

Nat Commun. 2018; 9: 95. Published online 2018 Jan 8. doi: 10.1038/s41467-017-02352-z

PMCID:: PMC5758830

Abstract Article PDF–2.9M

Select item 573762614.

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory

Timothy E. O’Sullivan, Lexus R. Johnson, Helen H. Kang, Joseph C. Sun

Immunity. Author manuscript; available in PMC 2017 Dec 20.

Published in final edited form as: Immunity. 2015 Aug 18; 43(2): 331–342. Published online 2015 Aug 4. doi: 10.1016/j.immuni.2015.07.012

PMCID:: PMC5737626

Abstract Article PDF–1.5M

Select item 569335515.

Endothelial cell autophagy maintains shear-stress-induced nitric oxide generation via glycolysis-dependent purinergic signaling to eNOS

Leena P Bharath, Jae Min Cho, Seul-Ki Park, Ting Ruan, Youyou Li, Robert Mueller, Tyler Bean, Van Reese, Russel S Richardson, Jinjin Cai, Ashot Sargsyan, Karla Pires, Pon Velayutham Anandh Babu, Sihem Boudina, Timothy E Graham, J David Symons

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Sep; 37(9): 1646–1656. Published online 2017 Jul 6. doi: 10.1161/ATVBAHA.117.309510

PMCID:: PMC5693355

Abstract Article PDF–2.8M

Select item 560267416.

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of T_H9 cells

Thaiz Rivera Vargas, Zhijian Cai, Yingying Shen, Magalie Dosset, Isis Benoit-Lizon, Tiffany Martin, Aurélie Roussey, Richard A. Flavell, François Ghiringhelli, Lionel Apetoh

Nat Commun. 2017; 8: 559. Published online 2017 Sep 15. doi: 10.1038/s41467-017-00468-w

PMCID:: PMC5602674

Abstract Article PDF–1.2M

Select item 559642717.

High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1

Pinglei Liu, Kun Liu, Haifeng Gu, Weixu Wang, Jiaqi Gong, Yingjie Zhu, Qian Zhao, Jiani Cao, Chunseng Han, Fei Gao, Quan Chen, Wei Li, Jianwei Jiao, Baoyang Hu, Qi Zhou, Tongbiao Zhao

Cell Death Differ. 2017 Oct; 24(10): 1672–1680. Published online 2017 Jun 16. doi: 10.1038/cdd.2017.90

PMCID:: PMC5596427

Abstract Article PDF–2.0M

Select item 529582118.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 512763819.

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Rebecca Rojansky, Moon-Yong Cha, David C Chan

eLife. 2016; 5: e17896. Published online 2016 Nov 17. doi: 10.7554/eLife.17896

PMCID:: PMC5127638

Abstract Article PDF–5.5M

Select item 510335820.

ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance

Kun Liu, Qian Zhao, Pinglei Liu, Jiani Cao, Jiaqi Gong, Chaoqun Wang, Weixu Wang, Xiaoyan Li, Hongyan Sun, Chao Zhang, Yufei Li, Minggui Jiang, Shaohua Zhu, Qingyuan Sun, Jianwei Jiao, Baoyang Hu, Xiaoyang Zhao, Wei Li, Quan Chen, Qi Zhou, Tongbiao Zhao

Autophagy. 2016; 12(11): 2000–2008. Published online 2016 Aug 11. doi: 10.1080/15548627.2016.1212786

PMCID:: PMC5103358

Abstract Article PDF–1.1M

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