U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 31

1.
GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation
Jeron Venhuizen, Maaike G. J. M. van Bergen, Saskia M. Bergevoet, Daan Gilissen, Cornelia G. Spruijt, Laura Wingens, Emile van den Akker, Michiel Vermeulen, Joop H. Jansen, Joost H. A. Martens, Bert A. van der Reijden
Commun Biol. 2024; 7: 374. Published online 2024 Mar 28. doi: 10.1038/s42003-024-06090-z
PMCID:
PMC10978956
AbstractArticlePDF–3.2M
2.
GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia
Longlong Liu, Pradeep Kumar Patnana, Xiaoqing Xie, Daria Frank, Subbaiah Chary Nimmagadda, Minhua Su, Donghua Zhang, Thorsten Koenig, Frank Rosenbauer, Marie Liebmann, Luisa Klotz, Wendan Xu, Jan Vorwerk, Felix Neumann, Jana Hüve, Andreas Unger, Jürgen Günther Okun, Bertram Opalka, Cyrus Khandanpour
Leukemia. 2022; 36(9): 2196–2207. Published online 2022 Jul 8. doi: 10.1038/s41375-022-01635-9
PMCID:
PMC9417998
AbstractArticlePDF–4.6M
3.
Dysregulation of oncogenic factors by GFI1B p32: investigation of a novel GFI1B germline mutation
Michela Faleschini, Nicole Papa, Marie-Christine Morel-Kopp, Caterina Marconi, Tania Giangregorio, Federica Melazzini, Valeria Bozzi, Marco Seri, Patrizia Noris, Alessandro Pecci, Anna Savoia, Roberta Bottega
Haematologica. 2022 Jan 1; 107(1): 260–267. Published online 2021 Jan 21. doi: 10.3324/haematol.2020.267328
PMCID:
PMC8719102
AbstractArticlePDF–6.0M
4.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
5.
Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium
Freya F. Bruveris, Elizabeth S. Ng, Ana Rita Leitoguinho, Ali Motazedian, Katerina Vlahos, Koula Sourris, Robyn Mayberry, Penelope McDonald, Lisa Azzola, Nadia M. Davidson, Alicia Oshlack, Edouard G. Stanley, Andrew G. Elefanty
Development. 2020 Oct 15; 147(20): dev193037. Published online 2020 Oct 29. doi: 10.1242/dev.193037
PMCID:
PMC7648599
AbstractArticle
6.
Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice
Hugues Beauchemin, Peiman Shooshtharizadeh, Jordan Pinder, Graham Dellaire, Tarik Möröy
Haematologica. 2020 Oct 1; 105(10): 2457–2470. Published online 2019 Nov 21. doi: 10.3324/haematol.2019.222596
PMCID:
PMC7556681
AbstractArticlePDF–5.5M
7.
Loss of myeloid‐specific lamin A/C drives lung metastasis through Gfi‐1 and C/EBPε‐mediated granulocytic differentiation
Hiroki Ishii, Woo‐Yong Park, Jaeyoung So, Skyler Kuhn, Vishal N. Koparde, Yanli Pang, Tim F. Greten, M. Christine Hollander, Li Yang
Mol Carcinog. 2020 Jul; 59(7): 679–690. Published online 2020 Jan 7. doi: 10.1002/mc.23147
PMCID:
PMC7282947
AbstractArticlePDF–3.5M
8.
Macrothrombocytopenia associated with a rare GFI1B missense variant confounding the presentation of immune thrombocytopenia
Aaron N. Cheng, Erik L. Bao, Claudia Fiorini, Vijay G. Sankaran
Pediatr Blood Cancer. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Pediatr Blood Cancer. 2019 Sep; 66(9): e27874. Published online 2019 Jun 17. doi: 10.1002/pbc.27874
PMCID:
PMC6646087
AbstractArticlePDF–419K
9.
Growth Factor Independence 1B-Mediated Transcriptional Repression and Lineage Allocation Require Lysine-Specific Demethylase 1-Dependent Recruitment of the BHC Complex
David McClellan, Mattie J. Casey, Diana Bareyan, Helena Lucente, Christopher Ours, Matthew Velinder, Jason Singer, Mehraju Din Lone, Wenxiang Sun, Yunuen Coria, Clinton C. Mason, Michael E. Engel
Mol Cell Biol. 2019 Jul 1; 39(13): e00020-19. Prepublished online 2019 Apr 15. Published online 2019 Jun 13. doi: 10.1128/MCB.00020-19
PMCID:
PMC6580704
AbstractArticlePDF–1.6M
10.
Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses
Rinske van Oorschot, Anna E. Marneth, Saskia M. Bergevoet, Maaike G.J.M. van Bergen, Kathelijne Peerlinck, Claire E. Lentaigne, Carolyn M. Millar, Sarah K. Westbury, Remi Favier, Wendy N. Erber, Ernest Turro, Joop H. Jansen, Willem H. Ouwehand, Harriet L. McKinney, NIHR BioResource Collaborative Group, Kate Downes, Kathleen Freson, Bert A. van der Reijden
Haematologica. 2019 Jun; 104(6): e260–e264. doi: 10.3324/haematol.2018.207712
PMCID:
PMC6545829
ArticlePDF–880K
11.
Mapping the genetic landscape of human cells
Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert
Cell. Author manuscript; available in PMC 2019 Aug 9.
Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010
PMCID:
PMC6426455
AbstractArticlePDF–3.6M
12.
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression
Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel
Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118
PMCID:
PMC6295165
AbstractArticlePDF–3.5M
13.
Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
Aniththa Thivakaran, Lacramioara Botezatu, Judith M. Hönes, Judith Schütte, Lothar Vassen, Yahya S. Al-Matary, Pradeep Patnana, Amos Zeller, Michael Heuser, Felicitas Thol, Razif Gabdoulline, Nadine Olberding, Daria Frank, Marina Suslo, Renata Köster, Klaus Lennartz, Andre Görgens, Bernd Giebel, Bertram Opalka, Ulrich Dührsen, Cyrus Khandanpour
Haematologica. 2018 Apr; 103(4): 614–625. Prepublished online 2018 Jan 11. doi: 10.3324/haematol.2017.167288
PMCID:
PMC5865438
AbstractArticlePDF–2.6M
14.
Combined alpha-delta platelet storage pool deficiency is associated with mutations in GFI1B
Carlos R. Ferreira, Dong Chen, Shirley M. Abraham, David R. Adams, Karen L. Simon, May C. Malicdan, Thomas C. Markello, Meral Gunay-Aygun, William A. Gahl
Mol Genet Metab. Author manuscript; available in PMC 2018 Mar 1.
Published in final edited form as: Mol Genet Metab. 2017 Mar; 120(3): 288–294. Published online 2016 Dec 18. doi: 10.1016/j.ymgme.2016.12.006
PMCID:
PMC5346474
AbstractArticlePDF–1.0M
15.
Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3 and Talin1
Divya Singh, Ghanshyam Upadhyay, Ananya Sengupta, Mohammed A. Biplob, Shaleen Chakyayil, Tiji George, Shireen Saleque
PLoS One. 2016; 11(10): e0164506. Published online 2016 Oct 21. doi: 10.1371/journal.pone.0164506
PMCID:
PMC5074496
AbstractArticlePDF–2.1M
16.
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis
Linda M. Polfus, Rajiv K. Khajuria, Ursula M. Schick, Nathan Pankratz, Raha Pazoki, Jennifer A. Brody, Ming-Huei Chen, Paul L. Auer, James S. Floyd, Jie Huang, Leslie Lange, Frank J.A. van Rooij, Richard A. Gibbs, Ginger Metcalf, Donna Muzny, Narayanan Veeraraghavan, Klaudia Walter, Lu Chen, Lisa Yanek, Lewis C. Becker, Gina M. Peloso, Aoi Wakabayashi, Mart Kals, Andres Metspalu, Tõnu Esko, Keolu Fox, Robert Wallace, Nora Franceshini, Nena Matijevic, Kenneth M. Rice, Traci M. Bartz, Leo-Pekka Lyytikäinen, Mika Kähönen, Terho Lehtimäki, Olli T. Raitakari, Ruifang Li-Gao, Dennis O. Mook-Kanamori, Guillaume Lettre, Cornelia M. van Duijn, Oscar H. Franco, Stephen S. Rich, Fernando Rivadeneira, Albert Hofman, André G. Uitterlinden, James G. Wilson, Bruce M. Psaty, Nicole Soranzo, Abbas Dehghan, Eric Boerwinkle, Xiaoling Zhang, Andrew D. Johnson, Christopher J. O’Donnell, Jill M. Johnsen, Alexander P. Reiner, Santhi K. Ganesh, Vijay G. Sankaran
Am J Hum Genet. 2016 Aug 4; 99(2): 481–488. Published online 2016 Aug 2. doi: 10.1016/j.ajhg.2016.06.016
Correction in:
Am J Hum Genet. 2016 Sep 1; 99(3): 785.
PMCID:
PMC4974169
AbstractArticlePDF–986K
17.
Control of developmentally primed erythroid genes by combinatorial co-repressor actions
Ralph Stadhouders, Alba Cico, Tharshana Stephen, Supat Thongjuea, Petros Kolovos, H. Irem Baymaz, Xiao Yu, Jeroen Demmers, Karel Bezstarosti, Alex Maas, Vilma Barroca, Christel Kockx, Zeliha Ozgur, Wilfred van Ijcken, Marie-Laure Arcangeli, Charlotte Andrieu-Soler, Boris Lenhard, Frank Grosveld, Eric Soler
Nat Commun. 2015; 6: 8893. Published online 2015 Nov 23. doi: 10.1038/ncomms9893
PMCID:
PMC4673834
AbstractArticlePDF–2.7M
18.
From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation
Tarik Möröy, Lothar Vassen, Brian Wilkes, Cyrus Khandanpour
Blood. 2015 Dec 10; 126(24): 2561–2569. Prepublished online 2015 Oct 7. doi: 10.1182/blood-2015-06-655043
PMCID:
PMC4671106
AbstractArticle
19.
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Paul A Northcott, Catherine Lee, Thomas Zichner, Adrian M Stütz, Serap Erkek, Daisuke Kawauchi, David JH Shih, Volker Hovestadt, Marc Zapatka, Dominik Sturm, David TW Jones, Marcel Kool, Marc Remke, Florence Cavalli, Scott Zuyderduyn, Gary Bader, Scott VandenBerg, Lourdes Adriana Esparza, Marina Ryzhova, Wei Wang, Andrea Wittmann, Sebastian Stark, Laura Sieber, Huriye Seker-Cin, Linda Linke, Fabian Kratochwil, Natalie Jäger, Ivo Buchhalter, Charles D Imbusch, Gideon Zipprich, Benjamin Raeder, Sabine Schmidt, Nicolle Diessl, Stephan Wolf, Stefan Wiemann, Benedikt Brors, Chris Lawerenz, Jürgen Eils, Hans-Jörg Warnatz, Thomas Risch, Marie-Laure Yaspo, Ursula D Weber, Cynthia C Bartholomae, Christof von Kalle, Eszter Turányi, Peter Hauser, Emma Sanden, Anna Darabi, Peter Siesjö, Jaroslav Sterba, Karel Zitterbart, David Sumerauer, Peter van Sluis, Rogier Versteeg, Richard Volckmann, Jan Koster, Martin U Schuhmann, Martin Ebinger, H. Leighton Grimes, Giles W Robinson, Amar Gajjar, Martin Mynarek, Katja von Hoff, Stefan Rutkowski, Torsten Pietsch, Wolfram Scheurlen, Jörg Felsberg, Guido Reifenberger, Andreas E Kulozik, Andreas von Deimlmg, Olaf Witt, Roland Eils, Richard J Gilbertson, Andrey Korshunov, Michael D Taylor, Peter Lichter, Jan O Korbel, Robert J Wechsler-Reya, Stefan M Pfister
Nature. Author manuscript; available in PMC 2015 Jul 24.
Published in final edited form as: Nature. 2014 Jul 24; 511(7510): 428–434. Published online 2014 Jun 22. doi: 10.1038/nature13379
PMCID:
PMC4201514
AbstractArticlePDF–6.7M
20.
Analysis of chromatin-state plasticity identifies cell-type–specific regulators of H3K27me3 patterns
Luca Pinello, Jian Xu, Stuart H. Orkin, Guo-Cheng Yuan
Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3): E344–E353. Published online 2014 Jan 6. doi: 10.1073/pnas.1322570111
PMCID:
PMC3903219
AbstractArticlePDF–1.9M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center