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Items: 1 to 20 of 32

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Myeloid SENP3 deficiency protects mice from diet and age-induced obesity via regulation of YAP1 SUMOylation
Yangjing Jiang, Min Liang, Long Chen, Jian Wang, Yijie Huang, Huanhuan Huo, Danrui Xiao, Yunwen Hu, Zi Wang, Qingqi Ji, Yanjie Li, Zhaohua Cai, Ben He
Cell Mol Life Sci. 2024 Dec; 81(1): 4. Published online 2023 Dec 9. doi: 10.1007/s00018-023-05050-w
PMCID:
PMC10710392
AbstractArticlePDF–9.0M
3.
SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury
Shuangjun He, Chenyu Fan, Yiming Ji, Qian Su, Feng Zhao, Cuiying Xie, Xuelian Chen, Yang Zhang, Yi Chen
Innate Immun. 2023 Jan; 29(1-2): 25–34. Published online 2023 Apr 5. doi: 10.1177/17534259231166212
PMCID:
PMC10164277
AbstractArticlePDF–3.6M
4.
Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage
Ximing Bao, Bin Liu, Yongquan Jiang, Tingting Feng, Wanxin Cao, Jiali Shi, Yiming Jiang, Xiaorui Chen, Jie Yang, Jiping Li, Zheng Zhou
Immun Inflamm Dis. 2023 Feb; 11(2): e781. Published online 2023 Feb 9. doi: 10.1002/iid3.781
PMCID:
PMC9910171
AbstractArticlePDF–2.2M
5.
Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity
Gaolei Hu, Yalan Chen, Xinyu Yang, Yang Wang, Jianli He, Tianshi Wang, Qiuju Fan, Liufu Deng, Jun Tu, Hongsheng Tan, Jinke Cheng
Cell Death Dis. 2022 Jul; 13(7): 640. Published online 2022 Jul 22. doi: 10.1038/s41419-022-05063-6
PMCID:
PMC9307842
AbstractArticlePDF–3.3M
6.
SENP3 loss promotes M2 macrophage polarization and breast cancer progression
Ming Xiao, Qi Bian, Yimin Lao, Jing Yi, Xueqing Sun, Xuxu Sun, Jie Yang
Mol Oncol. 2022 Feb; 16(4): 1026–1044. Published online 2021 May 29. doi: 10.1002/1878-0261.12967
PMCID:
PMC8847990
AbstractArticlePDF–10M
7.
Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development
Seiya Yamada, Ayaka Sato, Naotada Ishihara, Hiroki Akiyama, Shin-ichi Sakakibara
iScience. 2021 Dec 17; 24(12): 103484. Published online 2021 Dec 10. doi: 10.1016/j.isci.2021.103484
PMCID:
PMC8710555
AbstractArticlePDF–7.4M
8.
Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability
Zhaohua Cai, Zi Wang, Ruosen Yuan, Mingli Cui, Yimin Lao, Ying Wang, Peng Nie, Linghong Shen, Jing Yi, Ben He
EBioMedicine. 2021 May; 67: 103386. Published online 2021 May 14. doi: 10.1016/j.ebiom.2021.103386
PMCID:
PMC8138600
AbstractArticlePDF–4.0M
9.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
10.
Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression
Xiaoyu Zhang, Cuancuan Wang, Dan Zhao, Xuhong Chen, Chunyan Zhang, Jun Zheng, Xiaozhi Liu
PLoS One. 2020; 15(11): e0242606. Published online 2020 Nov 19. doi: 10.1371/journal.pone.0242606
PMCID:
PMC7676719
AbstractArticlePDF–2.6M
11.
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3
Kejia Liu, Chu Guo, Yimin Lao, Jie Yang, Fei Chen, Yuzheng Zhao, Yi Yang, Jie Yang, Jing Yi
Autophagy. 2020; 16(6): 975–990. Published online 2019 Aug 2. doi: 10.1080/15548627.2019.1647944
PMCID:
PMC7469448
AbstractArticlePDF–6.2M
12.
SENP3 in monocytes/macrophages up‐regulates tissue factor and mediates lipopolysaccharide‐induced acute lung injury by enhancing JNK phosphorylation
Xuelian Chen, Yimin Lao, Jing Yi, Jie Yang, Shuangjun He, Yi Chen
J Cell Mol Med. 2020 May; 24(10): 5454–5462. Published online 2020 Mar 31. doi: 10.1111/jcmm.15199
PMCID:
PMC7214145
AbstractArticlePDF–2.1M
13.
Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation
Cheng-Yi Yang, Ting-Hsuan Yu, Wan-Ling Wen, Pin Ling, Kuei-Sen Hsu
J Neurosci. 2019 Jun 19; 39(25): 4959–4975. doi: 10.1523/JNEUROSCI.2395-18.2019
PMCID:
PMC6670244
AbstractArticlePDF–3.4M
14.
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu, Lei Chen, Li-Ming Lu, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi, Qiang Zou
Nat Commun. 2018; 9: 3157. Published online 2018 Aug 8. doi: 10.1038/s41467-018-05676-6
PMCID:
PMC6082899
AbstractArticlePDF–2.6M
15.
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages
Yimin Lao, Kai Yang, Zhaojun Wang, Xueqing Sun, Qiang Zou, Xiaoyan Yu, Jinke Cheng, Xuemei Tong, Edward T. H. Yeh, Jie Yang, Jing Yi
J Biol Chem. 2018 Mar 16; 293(11): 3965–3980. Published online 2018 Jan 19. doi: 10.1074/jbc.M117.816769
PMCID:
PMC5857993
AbstractArticlePDF–2.9M
16.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
17.
Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks
Paulina A. Latos, Arnold R. Sienerth, Alexander Murray, Claire E. Senner, Masanaga Muto, Masahito Ikawa, David Oxley, Sarah Burge, Brian J. Cox, Myriam Hemberger
Genes Dev. 2015 Dec 1; 29(23): 2435–2448. doi: 10.1101/gad.268821.115
PMCID:
PMC4691948
AbstractArticlePDF–1.0M
18.
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger
Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776
PMCID:
PMC4525203
AbstractArticlePDF–1.9M
19.
SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
Chun Guo, Keri L Hildick, Jia Luo, Laura Dearden, Kevin A Wilkinson, Jeremy M Henley
EMBO J. 2013 May 29; 32(11): 1514–1528. Published online 2013 Mar 22. doi: 10.1038/emboj.2013.65
PMCID:
PMC3671254
AbstractArticlePDF–2.6M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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