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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102139732.

Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice

Fabian Baalmann, Jana Brendler, Anne Butthof, Yulia Popkova, Kathrin M. Engel, Jürgen Schiller, Karsten Winter, Vera Lede, Albert Ricken, Torsten Schöneberg, Angela Schulz

Front Cell Dev Biol. 2023; 11: 1128456. Published online 2023 May 11. doi: 10.3389/fcell.2023.1128456

PMCID:: PMC10213973

Abstract Article PDF–5.3M

Select item 95781403.

Effects of Purinergic Receptor Deletion or Pharmacologic Modulation on Pulmonary Inflammation in Mice

Gregory S. Whitehead, Tadeusz P. Karcz, Dilip K. Tosh, Young-Hwan Jung, Zhiwei Wen, Ryan G. Campbell, Varun Gopinatth, Zhan-Guo Gao, Kenneth A. Jacobson, Donald N. Cook

ACS Pharmacol Transl Sci. 2022 Oct 14; 5(10): 973–984. Published online 2022 Oct 5. doi: 10.1021/acsptsci.2c00128

PMCID:: PMC9578140

Abstract Article PDF–2.3M

Select item 94360064.

The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver

Ingmar Mederacke, Aveline Filliol, Silvia Affo, Ajay Nair, Celine Hernandez, Qiuyan Sun, Florian Hamberger, Francesco Brundu, Yu Chen, Aashreya Ravichandra, Peter Huebener, Helena Anke, Hongxue Shi, Raquel A. Martínez García de la Torre, James R. Smith, Neil C. Henderson, Florian W. R. Vondran, Carla V. Rothlin, Heike Baehre, Ira Tabas, Pau Sancho-Bru, Robert F. Schwabe

Sci Transl Med. Author manuscript; available in PMC 2022 Oct 6.

Published in final edited form as: Sci Transl Med. 2022 Apr 6; 14(639): eabe5795. Published online 2022 Apr 6. doi: 10.1126/scitranslmed.abe5795

PMCID:: PMC9436006

Abstract Article PDF–2.7M

Select item 90058045.

GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils

Chunxiao Liu, Mengze Zhou, Wenjiao Jiang, Shumin Ye, Sheng Tian, Cheng Jiang, Kun Hao, Huanqiu Li, Qinghua Hu

Front Immunol. 2022; 13: 870183. Published online 2022 Mar 30. doi: 10.3389/fimmu.2022.870183

PMCID:: PMC9005804

Abstract Article PDF–23M

Select item 89596016.

P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis

Jennifer Patritti Cram, Jianqiang Wu, Robert A Coover, Tilat A Rizvi, Katherine E Chaney, Ramya Ravindran, Jose A Cancelas, Robert J Spinner, Nancy Ratner

eLife. 2022; 11: e73511. Published online 2022 Mar 21. doi: 10.7554/eLife.73511

PMCID:: PMC8959601

Abstract Article PDF–14M

Select item 80118877.

UDP-glucose and P2Y₁₄ receptor amplify allergen-induced airway eosinophilia

Tadeusz P. Karcz, Gregory S. Whitehead, Keiko Nakano, Hideki Nakano, Sara A. Grimm, Jason G. Williams, Leesa J. Deterding, Kenneth A. Jacobson, Donald N. Cook

J Clin Invest. 2021 Apr 1; 131(7): e140709. Published online 2021 Apr 1. doi: 10.1172/JCI140709

PMCID:: PMC8011887

Abstract Article PDF–4.0M

Select item 73241868.

Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice

Maria Agustina Battistone, Alexandra C. Mendelsohn, Raul German Spallanzani, Andrew S. Allegretti, Rachel N. Liberman, Juliana Sesma, Sahir Kalim, Susan M. Wall, Joseph V. Bonventre, Eduardo R. Lazarowski, Dennis Brown, Sylvie Breton

J Clin Invest. 2020 Jul 1; 130(7): 3734–3749. Published online 2020 Jun 8. doi: 10.1172/JCI134791

PMCID:: PMC7324186

Abstract Article PDF–19M

Select item 72160669.

Role of UDP-Sugar Receptor P2Y₁₄ in Murine Osteoblasts

Nicholas Mikolajewicz, Svetlana V. Komarova

Int J Mol Sci. 2020 Apr; 21(8): 2747. Published online 2020 Apr 15. doi: 10.3390/ijms21082747

PMCID:: PMC7216066

Abstract Article PDF–2.9M

Select item 715645110.

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

Jingwei Ma, Keke Wei, Junwei Liu, Ke Tang, Huafeng Zhang, Liyan Zhu, Jie Chen, Fei Li, Pingwei Xu, Jie Chen, Jincheng Liu, Haiqing Fang, Liang Tang, Dianheng Wang, Liping Zeng, Weiwei Sun, Jing Xie, Yuying Liu, Bo Huang

Nat Commun. 2020; 11: 1769. Published online 2020 Apr 14. doi: 10.1038/s41467-020-15636-8

PMCID:: PMC7156451

Abstract Article PDF–2.1M

Select item 632983111.

Single-cell transcriptomic analysis of mouse neocortical development

Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka

Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9

PMCID:: PMC6329831

Abstract Article PDF–3.6M

Select item 598608012.

Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance

Justin S. A. Perry, Emilie V. Russler-Germain, You W. Zhou, Whitney Purtha, Matthew L. Cooper, Jaebok Choi, Mark A. Schroeder, Vanessa Salazar, Takeshi Egawa, Byeong-Chel Lee, Nada A. Abumrad, Brian S. Kim, Mark S. Anderson, John F. DiPersio, Chyi-Song Hsieh

Immunity. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: Immunity. 2018 May 15; 48(5): 923–936.e4. Published online 2018 May 8. doi: 10.1016/j.immuni.2018.04.007

Correction in:: Immunity. 2018 Jun 19; 48(6): 1271.

PMCID:: PMC5986080

Abstract Article PDF–3.8M

Select item 582374213.

P2Y14 Receptor Activation Decreases Interleukin-6 Production and Glioma GL261 Cell Proliferation in Microglial Transwell Cultures

Marjorie A. Curet, Jyoti J. Watters

J Neurooncol. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: J Neurooncol. 2018 Mar; 137(1): 23–31. Published online 2017 Nov 30. doi: 10.1007/s11060-017-2700-9

PMCID:: PMC5823742

Abstract Article PDF–921K

Select item 481366814.

Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Per Holmfeldt, Miguel Ganuza, Himangi Marathe, Bing He, Trent Hall, Guolian Kang, Joseph Moen, Jennifer Pardieck, Angelica C. Saulsberry, Alba Cico, Ludovic Gaut, Daniel McGoldrick, David Finkelstein, Kai Tan, Shannon McKinney-Freeman

J Exp Med. 2016 Mar 7; 213(3): 433–449. doi: 10.1084/jem.20150806

Correction in:: J Exp Med. 2016 Oct 17; 213(11): 2525.

PMCID:: PMC4813668

Abstract Article PDF–3.0M

Select item 415608915.

The G Protein-coupled Receptor P2Y₁₄ Influences Insulin Release and Smooth Muscle Function in Mice

Jaroslawna Meister, Diana Le Duc, Albert Ricken, Ralph Burkhardt, Joachim Thiery, Helga Pfannkuche, Tobias Polte, Johannes Grosse, Torsten Schöneberg, Angela Schulz

J Biol Chem. 2014 Aug 22; 289(34): 23353–23366. Published online 2014 Jul 3. doi: 10.1074/jbc.M114.580803