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Select item 110940291.

Mcph1, mutated in primary microcephaly, is also crucial for erythropoiesis

Yoann Vial, Jeannette Nardelli, Adeline A Bonnard, Justine Rousselot, Michèle Souyri, Pierre Gressens, Hélène Cavé, Séverine Drunat

EMBO Rep. 2024 May; 25(5): 2418–2440. Published online 2024 Apr 11. doi: 10.1038/s44319-024-00123-8

PMCID:: PMC11094029

Abstract Article PDF–10M

Select item 110833512.

Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence

Yi-Nan Jiang, Yizhen Gao, Xianxin Lai, Xinjie Li, Gen Liu, Mingmei Ding, Zhiyi Wang, Zixiang Guo, Yinying Qin, Xin Li, Litao Sun, Zhao-Qi Wang, Zhong-Wei Zhou

Int J Mol Sci. 2024 May; 25(9): 4597. Published online 2024 Apr 23. doi: 10.3390/ijms25094597

PMCID:: PMC11083351

Abstract Article PDF–7.4M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104535994.

Skin-Grafting and Dendritic Cell “Boosted” Humanized Mouse Models Allow the Pre-Clinical Evaluation of Therapeutic Cancer Vaccines

Bijun Zeng, Davide Moi, Lynn Tolley, Natalie Molotkov, Ian Hector Frazer, Christopher Perry, Riccardo Dolcetti, Roberta Mazzieri, Jazmina L. G. Cruz

Cells. 2023 Aug; 12(16): 2094. Published online 2023 Aug 18. doi: 10.3390/cells12162094

PMCID:: PMC10453599

Abstract Article PDF–3.4M

Select item 102858795.

KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection

Nicole Caduff, Donal McHugh, Lisa Rieble, Catherine S. Forconi, John M. Ong’echa, Peter O. Oluoch, Ana Raykova, Anita Murer, Michelle Böni, Lara Zuppiger, Thomas F. Schulz, David J. Blackbourn, Obinna Chijioke, Ann M. Moormann, Christian Münz

Cell Rep. Author manuscript; available in PMC 2023 Jun 22.

Published in final edited form as: Cell Rep. 2021 May 4; 35(5): 109056. doi: 10.1016/j.celrep.2021.109056

PMCID:: PMC10285879

Abstract Article PDF–1.1M

Select item 98374426.

Antigen-guided depletion of anti-HLA antibody–producing cells by HLA-Fc fusion proteins

Ashlee M. Webber, Tara R. Bradstreet, Xiaoli Wang, Hongjie Guo, Christopher A. Nelson, Daved H. Fremont, Brian T. Edelson, Chang Liu

Blood. 2022 Oct 20; 140(16): 1803–1815. Published online 2022 Aug 18. doi: 10.1182/blood.2022016376

PMCID:: PMC9837442

Abstract Article

Select item 94550547.

The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice

Yaru Wang, Wen Zong, Wenli Sun, Chengyan Chen, Zhao-Qi Wang, Tangliang Li

Cells. 2022 Sep; 11(17): 2715. Published online 2022 Aug 31. doi: 10.3390/cells11172715

PMCID:: PMC9455054

Abstract Article PDF–4.2M

Select item 91174688.

Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function

Paramita Chakraborty, Rasesh Y. Parikh, Seungho Choi, Danh Tran, Monika Gooz, Zachariah T. Hedley, Do-Sung Kim, Dariusz Pytel, Inhong Kang, Satish N. Nadig, Gyda C. Beeson, Lauren Ball, Meenal Mehrotra, Hongjun Wang, Stefano Berto, Viswanathan Palanisamy, Hong Li, Shilpak Chatterjee, Paulo C. Rodriguez, Eduardo N. Maldonado, J. Alan Diehl, Vamsi K. Gangaraju, Shikhar Mehrotra

Cancer Res. Author manuscript; available in PMC 2022 Nov 16.

Published in final edited form as: Cancer Res. 2022 May 16; 82(10): 1969–1990. doi: 10.1158/0008-5472.CAN-21-3155

PMCID:: PMC9117468

Abstract Article PDF–3.2M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 816710710.

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Uda Y. Ho, Chun-Wei Allen Feng, Yvonne Y. Yeap, Amanda L. Bain, Zhe Wei, Belal Shohayeb, Melissa E. Reichelt, Hayden Homer, Kum Kum Khanna, Josephine Bowles, Dominic C. H. Ng

Commun Biol. 2021; 4: 645. Published online 2021 May 31. doi: 10.1038/s42003-021-02171-5

PMCID:: PMC8167107

Abstract Article PDF–7.0M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 786265312.

The N-terminal BRCT domain determines MCPH1 function in brain development and fertility

Xiaoqian Liu, Nadine Schneble-Löhnert, Martina Kristofova, Xiaobing Qing, Jan Labisch, Susanne Hofmann, Sandra Ehrenberg, Mara Sannai, Tjard Jörß, Alessandro Ori, Maren Godmann, Zhao-Qi Wang

Cell Death Dis. 2021 Feb; 12(2): 143. Published online 2021 Feb 1. doi: 10.1038/s41419-021-03406-3

PMCID:: PMC7862653

Abstract Article PDF–3.9M

Select item 688982113.

Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

Paramita Chakraborty, Silvia G. Vaena, Krishnamurthy Thyagarajan, Shilpak Chatterjee, Amir Al-Khami, Shanmugam Panneer Selvam, Hung Nguyen, Inhong Kang, Megan W. Wyatt, Uday Baliga, Zachariah Hedley, Rose N. Ngang, Beichu Guo, Gyda C. Beeson, Shahid Husain, Chrystal M. Paulos, Craig C. Beeson, Michael J. Zilliox, Elizabeth G. Hill, Meenal Mehrotra, Xue-Zhong Yu, Besim Ogretmen, Shikhar Mehrotra

Cell Rep. Author manuscript; available in PMC 2019 Dec 3.

Published in final edited form as: Cell Rep. 2019 Aug 13; 28(7): 1879–1893.e7. doi: 10.1016/j.celrep.2019.07.044

PMCID:: PMC6889821

Abstract Article PDF–2.4M

Select item 646391514.

Naturally presented HLA class I–restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes

Cristina Calviño-Sampedro, Iria Gomez-Tourino, Oscar J. Cordero, Pedro A. Reche, Marta Gómez-Perosanz, Jose Luis Sánchez-Trincado, Miguel Ángel Rodríguez, Aurelio M. Sueiro, Juan E. Viñuela, Rubén Varela Calviño

FASEB J. 2019 May; 33(5): 6390–6401. Published online 2019 Feb 28. doi: 10.1096/fj.201802270R

PMCID:: PMC6463915

Abstract Article

Select item 645951015.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 641378616.

Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation

Natalia F. Smirnova, Thomas M. Conlon, Carmela Morrone, Peter Dorfmuller, Marc Humbert, Georgios T. Stathopoulos, Stephan Umkehrer, Franz Pfeiffer, Ali Ö. Yildirim, Oliver Eickelberg

JCI Insight. 2019 Feb 7; 4(3): e123971. Published online 2019 Feb 7. doi: 10.1172/jci.insight.123971

PMCID:: PMC6413786

Abstract Article PDF–46M

Select item 639641417.

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis

Leslie O. Goodwin, Erik Splinter, Tiffany L. Davis, Rachel Urban, Hao He, Robert E. Braun, Elissa J. Chesler, Vivek Kumar, Max van Min, Juliet Ndukum, Vivek M. Philip, Laura G. Reinholdt, Karen Svenson, Jacqueline K. White, Michael Sasner, Cathleen Lutz, Stephen A. Murray

Genome Res. 2019 Mar; 29(3): 494–505. doi: 10.1101/gr.233866.117

PMCID:: PMC6396414

Abstract Article PDF–4.8M

Select item 626200118.

Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

Florian Douam, Carly G. K. Ziegler, Gabriela Hrebikova, Bruno Fant, Robert Leach, Lance Parsons, Wei Wang, Jenna M. Gaska, Benjamin Y. Winer, Brigitte Heller, Alex K. Shalek, Alexander Ploss

Nat Commun. 2018; 9: 5031. Published online 2018 Nov 28. doi: 10.1038/s41467-018-07478-2

PMCID:: PMC6262001

Abstract Article PDF–2.9M

Select item 599176819.

Nuclear m⁶A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

Seth D. Kasowitz, Jun Ma, Stephen J. Anderson, N. Adrian Leu, Yang Xu, Brian D. Gregory, Richard M. Schultz, P. Jeremy Wang

PLoS Genet. 2018 May; 14(5): e1007412. Published online 2018 May 25. doi: 10.1371/journal.pgen.1007412

PMCID:: PMC5991768

Abstract Article PDF–19M

Select item 583704820.

CD38-NAD⁺Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

Shilpak Chatterjee, Anusara Daenthanasanmak, Paramita Chakraborty, Megan W. Wyatt, Payal Dhar, Shanmugam Panneer Selvam, Jianing Fu, Jinyu Zhang, Hung Nguyen, Inhong Kang, Kyle Toth, Mazen Al-Homrani, Mahvash Husain, Gyda Beeson, Lauren Ball, Kristi Helke, Shahid Husain, Elizabeth Garrett-Mayer, Gary Hardiman, Meenal Mehrotra, Michael I. Nishimura, Craig C. Beeson, Melanie Gubbels Bupp, Jennifer Wu, Besim Ogretmen, Chrystal M. Paulos, Jeffery Rathmell, Xue-Zhong Yu, Shikhar Mehrotra

Cell Metab. Author manuscript; available in PMC 2018 Mar 5.

Published in final edited form as: Cell Metab. 2018 Jan 9; 27(1): 85–100.e8. Published online 2017 Nov 9. doi: 10.1016/j.cmet.2017.10.006

PMCID:: PMC5837048

Abstract Article PDF–1.6M

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