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Items: 1 to 20 of 51

1.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation
Coraline Mlynarczyk, Matt Teater, Juhee Pae, Christopher R. Chin, Ling Wang, Theinmozhi Arulraj, Darko Barisic, Antonin Papin, Kenneth B. Hoehn, Ekaterina Kots, Jonatan Ersching, Arnab Bandyopadhyay, Ersilia Barin, Hui Xian Poh, Chiara M. Evans, Amy Chadburn, Zhengming Chen, Hao Shen, Hannah M. Isles, Benedikt Pelzer, Ioanna Tsialta, Ashley S. Doane, Huimin Geng, Muhammad Hassan Rehman, Jonah Melnick, Wyatt Morgan, Diu T. T. Nguyen, Olivier Elemento, Michael G. Kharas, Samie R. Jaffrey, David W. Scott, George Khelashvili, Michael Meyer-Hermann, Gabriel D. Victora, Ari Melnick
Science. Author manuscript; available in PMC 2023 Sep 22.
Published in final edited form as: Science. 2023 Jan 20; 379(6629): eabj7412. Published online 2023 Jan 20. doi: 10.1126/science.abj7412
PMCID:
PMC10515739
AbstractArticlePDF–3.1M
2.
B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection
Spencer T. Chen, Thiago Y. Oliveira, Anna Gazumyan, Melissa Cipolla, Michel C. Nussenzweig
Immunity. Author manuscript; available in PMC 2023 Aug 14.
Published in final edited form as: Immunity. 2023 Mar 14; 56(3): 547–561.e7. Published online 2023 Mar 6. doi: 10.1016/j.immuni.2023.02.003
PMCID:
PMC10424567
AbstractArticlePDF–3.0M
3.
Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis
Sharon L. Ford, Kim M. O’Sullivan, A. Richard Kitching, Stephen R. Holdsworth, Poh Yi Gan, Shaun A. Summers
Int J Mol Sci. 2023 Jan; 24(2): 1339. Published online 2023 Jan 10. doi: 10.3390/ijms24021339
PMCID:
PMC9864438
AbstractArticlePDF–2.8M
4.
Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength
Zhixin Jing, Mark J. McCarron, Michael L. Dustin, David R. Fooksman
Cell Rep. Author manuscript; available in PMC 2022 Jun 9.
Published in final edited form as: Cell Rep. 2022 May 3; 39(5): 110763. doi: 10.1016/j.celrep.2022.110763
PMCID:
PMC9178878
AbstractArticlePDF–2.7M
5.
Coordinated changes in glycosylation regulate the germinal center through CD22
Jhon R. Enterina, Susmita Sarkar, Laura Streith, Jaesoo Jung, Britni M. Arlian, Sarah J. Meyer, Hiromu Takematsu, Changchun Xiao, Troy A. Baldwin, Lars Nitschke, Mark J. Shlomchick, James C. Paulson, Matthew S. Macauley
Cell Rep. Author manuscript; available in PMC 2022 Apr 19.
Published in final edited form as: Cell Rep. 2022 Mar 15; 38(11): 110512. doi: 10.1016/j.celrep.2022.110512
PMCID:
PMC9018098
AbstractArticlePDF–2.9M
6.
Dynamic Regulation of Tfh Selection During the Germinal Center Reaction
Julia Merkenschlager, Shlomo Finkin, Victor Ramos, Julian Kraft, Melissa Cipolla, Carla R. Nowosad, Harald Hartweger, Wenzhu Zhang, Paul Dominic B. Olinares, Anna Gazumyan, Thiago Y. Oliveira, Brian T. Chait, Michel C. Nussenzweig
Nature. Author manuscript; available in PMC 2021 Aug 3.
Published in final edited form as: Nature. 2021 Mar; 591(7850): 458–463. Published online 2021 Feb 3. doi: 10.1038/s41586-021-03187-x
PMCID:
PMC7979475
AbstractArticlePDF–2.3M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model
Sadia Mehdi, Elizabeth Macdonald, Kristianne Galpin, David A. Landry, Galaxia Rodriguez, Barbara Vanderhyden, Dimcho Bachvarov
Int J Mol Sci. 2020 Jul; 21(14): 4992. Published online 2020 Jul 15. doi: 10.3390/ijms21144992
PMCID:
PMC7404269
AbstractArticlePDF–3.2M
9.
Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development
Dong Liu, Anastasia I. Kousa, Kathy E. O'Neill, Paul Rouse, Martyna Popis, Alison M. Farley, Simon R. Tomlinson, Svetlana Ulyanchenko, Francois Guillemot, Philip A. Seymour, Mette C. Jørgensen, Palle Serup, Ute Koch, Freddy Radtke, C. Clare Blackburn
Development. 2020 Jun 15; 147(12): dev178582. Published online 2020 Jun 22. doi: 10.1242/dev.178582
PMCID:
PMC7328009
AbstractArticle
10.
NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development
Jie Li, Julie Gordon, Edward L. Y. Chen, Shiyun Xiao, Luying Wu, Juan Carlos Zúñiga-Pflücker, Nancy R. Manley
Development. 2020 Jun 15; 147(12): dev178988. Published online 2020 Jun 22. doi: 10.1242/dev.178988
PMCID:
PMC7328004
AbstractArticle
11.
Protein amounts of the MYC transcription factor determine germinal center B cell division capacity
Shlomo Finkin, Harald Hartweger, Thiago Y. Oliveira, Ervin E. Kara, Michel C. Nussenzweig
Immunity. Author manuscript; available in PMC 2020 Aug 20.
Published in final edited form as: Immunity. 2019 Aug 20; 51(2): 324–336.e5. Published online 2019 Jul 23. doi: 10.1016/j.immuni.2019.06.013
PMCID:
PMC6703930
AbstractArticlePDF–2.3M
12.
Genetic identification of Ly75 as a novel quantitative trait gene for resistance to obesity in mice
Keita Makino, Akira Ishikawa
Sci Rep. 2018; 8: 17658. Published online 2018 Dec 5. doi: 10.1038/s41598-018-36073-0
PMCID:
PMC6281609
AbstractArticlePDF–2.2M
13.
ICAMs support B cell interactions with T follicular helper cells and promote clonal selection
Irina Zaretsky, Ofir Atrakchi, Roei D. Mazor, Liat Stoler-Barak, Adi Biram, Sara W. Feigelson, Alexander D. Gitlin, Britta Engelhardt, Ziv Shulman
J Exp Med. 2017 Nov 6; 214(11): 3435–3448. doi: 10.1084/jem.20171129
PMCID:
PMC5679169
AbstractArticlePDF–2.1M
14.
CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in HBsAg transgenic mice by promoting the interaction of NKT cells with Kupffer cells
Xin Hou, Xiaolei Hao, Meijuan Zheng, Congfei Xu, Jun Wang, Rongbin Zhou, Zhigang Tian
Cell Mol Immunol. 2017 Aug; 14(8): 675–684. Published online 2016 Apr 4. doi: 10.1038/cmi.2015.111
PMCID:
PMC5549602
AbstractArticlePDF–2.4M
15.
The cell cycle inhibitor Cdkn1a regulates Langerhans cell radiation resistance and promotes T regulatory cell generation upon exposure to ionizing irradiation
Jeremy G. Price, Juliana Idoyaga, Hélène Salmon, Brandon Hogstad, Carolina L. Bigarella, Saghi Ghaffari, Marylene Leboeuf, Miriam Merad
Nat Immunol. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Nat Immunol. 2015 Oct; 16(10): 1060–1068. Published online 2015 Sep 7. doi: 10.1038/ni.3270
PMCID:
PMC4620552
AbstractArticlePDF–802K
16.
Dynamic signaling by T follicular helper cells during germinal center B cell selection
Ziv Shulman, Alexander D. Gitlin, Jason S. Weinstein, Begoña Lainez, Enric Esplugues, Richard A. Flavell, Joseph E. Craft, Michel C. Nussenzweig
Science. Author manuscript; available in PMC 2015 Jul 29.
Published in final edited form as: Science. 2014 Aug 29; 345(6200): 1058–1062. doi: 10.1126/science.1257861
PMCID:
PMC4519234
AbstractArticlePDF–1.1M
17.
DNA vaccines encoding DEC205-targeted antigens: immunity or tolerance?
Thomas Niezold, Michael Storcksdieck genannt Bonsmann, André Maaske, Vladimir Temchura, Vanessa Heinecke, Drew Hannaman, Jan Buer, Christina Ehrhardt, Wiebke Hansen, Klaus Überla, Matthias Tenbusch
Immunology. 2015 Aug; 145(4): 519–533. Published online 2015 Apr 30. doi: 10.1111/imm.12467
PMCID:
PMC4515132
AbstractArticlePDF–793K
18.
The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells
Takeshi Nitta, Ryunosuke Muro, Yukiko Shimizu, Sachiko Nitta, Hiroyo Oda, Yuki Ohte, Motohito Goto, Rieko Yanobu-Takanashi, Tomoya Narita, Hiroshi Takayanagi, Hisataka Yasuda, Tadashi Okamura, Shigeo Murata, Harumi Suzuki
EMBO Rep. 2015 May; 16(5): 638–653. Published online 2015 Mar 13. doi: 10.15252/embr.201540096
PMCID:
PMC4428049
AbstractArticlePDF–3.2M
19.
Clonal selection in the germinal center by regulated proliferation and hypermutation
Alexander D. Gitlin, Ziv Shulman, Michel C. Nussenzweig
Nature. Author manuscript; available in PMC 2014 Dec 19.
Published in final edited form as: Nature. 2014 May 29; 509(7502): 637–640. Published online 2014 May 4. doi: 10.1038/nature13300
PMCID:
PMC4271732
AbstractArticlePDF–1.8M
20.
Fine Mapping and Candidate Gene Search of Quantitative Trait Loci for Growth and Obesity Using Mouse Intersubspecific Subcongenic Intercrosses and Exome Sequencing
Akira Ishikawa, Sin-ichiro Okuno
PLoS One. 2014; 9(11): e113233. Published online 2014 Nov 14. doi: 10.1371/journal.pone.0113233
PMCID:
PMC4232600
AbstractArticlePDF–693K

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