PMC Links for GEO Profiles (Select 121821987) - PMC

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 112198624.

A second hotspot for pathogenic exon-skipping variants in CDC45

Kelly Schoch, Mischa S. G. Ruegg, Bridget J. Fellows, Joseph Cao, Sabine Uhrig, Stephanie Einsele-Scholz, Saskia Biskup, Samuel R. A. Hawarden, Vincenzo Salpietro, Valeria Capra, Undiagnosed Diseases Network, Chris M. Brown, Andrea Accogli, Vandana Shashi, Louise S. Bicknell

Eur J Hum Genet. 2024 Jul; 32(7): 786–794. Published online 2024 Mar 11. doi: 10.1038/s41431-024-01583-1

PMCID:: PMC11219862

Abstract Article PDF–2.2M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 109565186.

Validation of CDC45 as a novel biomarker for diagnosis and prognosis of gastric cancer

Lihua Wu, Gan Gao, Hui Mi, Zhou Luo, Zheng Wang, Yongdong Liu, Liangyan Wu, Haihua Long, Yongqi Shen

PeerJ. 2024; 12: e17130. Published online 2024 Mar 18. doi: 10.7717/peerj.17130

PMCID:: PMC10956518

Abstract Article PDF–19M

Select item 107301437.

IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification

Tao Wu, Li Liao, Tao Wu, Shuai Chen, Qilin Yi, Min Xu

Cell Cycle. 2023; 22(20): 2245–2263. Published online 2023 Dec 15. doi: 10.1080/15384101.2023.2283328

PMCID:: PMC10730143

Abstract Article PDF–5.2M

Select item 104498958.

RNAPII-dependent ATM signaling at collisions with replication forks

Elias Einig, Chao Jin, Valentina Andrioletti, Boris Macek, Nikita Popov

Nat Commun. 2023; 14: 5147. Published online 2023 Aug 24. doi: 10.1038/s41467-023-40924-4

PMCID:: PMC10449895

Abstract Article PDF–2.2M

Select item 103986609.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 1027947210.

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

Cell Rep. Author manuscript; available in PMC 2023 Jun 19.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496

PMCID:: PMC10279472

Abstract Article PDF–2.9M

Select item 948193311.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 947898812.

Systematic pan-cancer analysis identifies CDC45 as having an oncogenic role in human cancers

Yalin Lu, Xingjie Chen, Fang Liu, Hao Yu, Yu Zhang, Kangjie Du, Yang Nan, Qiang Huang

Oncol Rep. 2022 Oct; 48(4): 185. Published online 2022 Sep 8. doi: 10.3892/or.2022.8400

PMCID:: PMC9478988

Abstract Article PDF–14M

Select item 910523513.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 889702214.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 889438015.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2

PMCID:: PMC8894380

Abstract Article PDF–5.6M

Select item 850171316.

CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis

Rongcai Liu, Weimin Dai, An Wu, Yunping Li

BMC Cancer. 2021; 21: 1090. Published online 2021 Oct 9. doi: 10.1186/s12885-021-08803-7

PMCID:: PMC8501713

Abstract Article PDF–4.3M

Select item 835296417.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 833109218.

Reconstitution of human CMG helicase ubiquitylation by CUL2^LRR1 and multiple E2 enzymes

Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P.M. Labib

Biochem J. 2021 Jul 30; 478(14): 2825–2842. Prepublished online 2021 Jun 29. Published online 2021 Jul 23. doi: 10.1042/BCJ20210315

PMCID:: PMC8331092

Abstract Article PDF–1.9M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 796055020.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

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