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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108911542.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 96436613.

Neutrophil and macrophage NADPH oxidase 2 (NOX2) differentially control responses to inflammation and to Aspergillus fumigatus in mice

Rachel A. Idol, Sourav Bhattacharya, Guangming Huang, Zhimin Song, Anna Huttenlocher, Nancy P. Keller, Mary C. Dinauer

J Immunol. Author manuscript; available in PMC 2023 Nov 15.

Published in final edited form as: J Immunol. 2022 Nov 15; 209(10): 1960–1972. doi: 10.4049/jimmunol.2200543

PMCID:: PMC9643661

Abstract Article PDF–3.3M

Select item 91012494.

Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice

Sourav Bhattacharya, Rachel A. Idol, Wei Yang, Jorge David Rojas Márquez, Yanan Li, Guangming Huang, Wandy L. Beatty, Jeffrey J. Atkinson, John H. Brumell, Juhi Bagaitkar, Jeffrey A. Magee, Mary C. Dinauer

Blood. 2022 May 12; 139(19): 2855–2870. doi: 10.1182/blood.2021015365

PMCID:: PMC9101249

Abstract Article

Select item 81635035.

A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

Tania Lebratti, Ying Shiang Lim, Adjoa Cofie, Prabhakar Andhey, Xiaoping Jiang, Jason Scott, Maria Rita Fabbrizi, Ayşe Naz Ozantürk, Christine Pham, Regina Clemens, Maxim Artyomov, Mary Dinauer, Haina Shin

eLife. 2021; 10: e65762. Published online 2021 May 28. doi: 10.7554/eLife.65762

PMCID:: PMC8163503

Abstract Article PDF–2.9M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 72636718.

A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation

Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams

G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128

PMCID:: PMC7263671

Abstract Article PDF–1.0M

Select item 68318359.

Serum response factor (SRF) promotes ROS generation and hepatic stellate cell activation by epigenetically stimulating NCF1/2 transcription

Ming Kong, Xuyang Chen, Fangqiao Lv, Haozhen Ren, Zhiwen Fan, Hao Qin, Liming Yu, Xiaolei Shi, Yong Xu

Redox Biol. 2019 Sep; 26: 101302. Published online 2019 Aug 15. doi: 10.1016/j.redox.2019.101302

PMCID:: PMC6831835

Abstract Article PDF–3.6M

Select item 662225510.

NADPH Oxidase Mediates Depressive Behavior Induced by Chronic Stress in Mice

Ji-Seon Seo, Jin-Young Park, Juli Choi, Tae-Kyung Kim, Joo-Hyun Shin, Ja-Kyeong Lee, Pyung-Lim Han

J Neurosci. 2012 Jul 11; 32(28): 9690–9699. doi: 10.1523/JNEUROSCI.0794-12.2012

PMCID:: PMC6622255

Abstract Article PDF–2.1M

Select item 645951011.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 622103312.

Pulmonary metastatic colonisation and granulomas in NOX2‐deficient mice

Louise van der Weyden, Anneliese O Speak, Agnieszka Swiatkowska, Simon Clare, Andrea Schejtman, Giorgia Santilli, Mark J Arends, David J Adams

J Pathol. 2018 Nov; 246(3): 300–310. Published online 2018 Sep 19. doi: 10.1002/path.5140

PMCID:: PMC6221033

Abstract Article PDF–1.8M

Select item 595322013.

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Shao-Ming Wang, Sher-Wei Lim, Ya-Han Wang, Hong-Yi Lin, Ming-Derg Lai, Chiung-Yuan Ko, Ju-Ming Wang

Redox Biol. 2018 Jun; 16: 104–112. Published online 2018 Feb 16. doi: 10.1016/j.redox.2018.02.011

PMCID:: PMC5953220

Abstract Article PDF–1.1M

Select item 538122614.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 504520015.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 363381116.

p67^phox terminates the phospholipase A₂-derived signal for activation of NADPH oxidase (NOX2)

Saikumari Y. Krishnaiah, Chandra Dodia, Sheldon I. Feinstein, Aron B. Fisher

FASEB J. 2013 May; 27(5): 2066–2073. doi: 10.1096/fj.12-222133

PMCID:: PMC3633811

Abstract Article

Select item 357241017.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 326700018.

Cytosolic, but not mitochondrial, oxidative stress likely contributes to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice

Yan Li, Adam R. Wende, Orathai Nunthakungwan, Yujia Huang, Eric Hu, Huifeng Jin, Sihem Boudina, E. Dale Abel, Thunder Jalili

FEBS J. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: FEBS J. 2012 Feb; 279(4): 599–611. Published online 2012 Jan 9. doi: 10.1111/j.1742-4658.2011.08450.x

PMCID:: PMC3267000

Abstract Article PDF–792K

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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