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Items: 1 to 20 of 701

1.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S. Varghese, Pauline Chabosseau, Sayed M. Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J. Withers, Guy A. Rutter, Steven J. Millership
Diabetologia. 2024; 67(6): 1079–1094. Published online 2024 Mar 21. doi: 10.1007/s00125-024-06123-6
PMCID:
PMC11058053
AbstractArticlePDF–7.7M
2.
NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover
Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning
Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946
PMCID:
PMC10945349
AbstractArticlePDF–9.7M
3.
Complement Cascade Proteins Correlate with Fibrosis and Inflammation in Early-Stage Type 1 Diabetic Kidney Disease in the Ins2Akita Mouse Model
Aggeliki Tserga, Jean Sébastien Saulnier-Blache, Kostantinos Palamaris, Despoina Pouloudi, Harikleia Gakiopoulou, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos Makridakis
Int J Mol Sci. 2024 Feb; 25(3): 1387. Published online 2024 Jan 23. doi: 10.3390/ijms25031387
PMCID:
PMC10855735
AbstractArticlePDF–5.0M
4.
Gestational diabetes in mice induces hematopoietic memory that affects the long-term health of the offspring
Vinothini Govindarajah, Masahide Sakabe, Samantha Good, Michael Solomon, Ashok Arasu, Nong Chen, Xuan Zhang, H. Leighton Grimes, Ady Kendler, Mei Xin, Damien Reynaud
J Clin Invest. 2024 Jan 16; 134(2): e169730. Published online 2024 Jan 16. doi: 10.1172/JCI169730
PMCID:
PMC10786695
AbstractArticlePDF–1.9M
5.
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
Samuel Philip Nobs, Aleksandra A. Kolodziejczyk, Lital Adler, Nir Horesh, Christine Botscharnikow, Ella Herzog, Gayatree Mohapatra, Sophia Hejndorf, Ryan-James Hodgetts, Igor Spivak, Lena Schorr, Leviel Fluhr, Denise Kviatcovsky, Anish Zacharia, Suzanne Njuki, Dinorah Barasch, Noa Stettner, Mally Dori-Bachash, Alon Harmelin, Alexander Brandis, Tevie Mehlman, Ayelet Erez, Yiming He, Sara Ferrini, Jens Puschhof, Hagit Shapiro, Manfred Kopf, Arieh Moussaieff, Suhaib K. Abdeen, Eran Elinav
Nature. 2023; 624(7992): 645–652. Published online 2023 Dec 13. doi: 10.1038/s41586-023-06803-0
PMCID:
PMC10733144
AbstractArticlePDF–13M
6.
Inhibition of neutrophil extracellular trap formation alleviates vascular dysfunction in type 1 diabetic mice
Chao Liu, Srilakshmi Yalavarthi, Ajay Tambralli, Lixia Zeng, Christine E. Rysenga, Nikoo Alizadeh, Lucas Hudgins, Wenying Liang, Somanathapura K. NaveenKumar, Hui Shi, Miriam A. Shelef, Kevin B. Atkins, Subramaniam Pennathur, Jason S. Knight
Sci Adv. 2023 Oct 27; 9(43): eadj1019. Published online 2023 Oct 25. doi: 10.1126/sciadv.adj1019
PMCID:
PMC10599623
AbstractArticlePDF–1.3M
7.
NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development
Romana Bohuslavova, Valeria Fabriciova, Ondrej Smolik, Laura Lebrón-Mora, Pavel Abaffy, Sarka Benesova, Daniel Zucha, Lukas Valihrach, Zuzana Berkova, Frantisek Saudek, Gabriela Pavlinkova
Nat Commun. 2023; 14: 5554. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41306-6
PMCID:
PMC10492842
AbstractArticlePDF–15M
8.
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih
eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006
PMCID:
PMC10482429
AbstractArticlePDF–26M
9.
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy
Gianpaolo Zerbini, Silvia Maestroni, Ilaria Viganò, Andrea Mosca, Renata Paleari, Daniela Gabellini, Silvia Galbiati, Paolo Rama
Int J Mol Sci. 2023 Aug; 24(16): 12672. Published online 2023 Aug 11. doi: 10.3390/ijms241612672
PMCID:
PMC10454227
AbstractArticlePDF–4.1M
10.
The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity
Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter
Mol Metab. 2023 Oct; 76: 101785. Published online 2023 Aug 1. doi: 10.1016/j.molmet.2023.101785
PMCID:
PMC10448474
AbstractArticlePDF–4.8M
11.
Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain
Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel
Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123
PMCID:
PMC10393193
AbstractArticlePDF–22M
12.
SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes
Lakshini Yasaswi Herat, Jennifer Rose Matthews, Moira Hibbs, Elizabeth Piroska Rakoczy, Markus Peter Schlaich, Vance Bruce Matthews
iScience. 2023 Aug 18; 26(8): 107260. Published online 2023 Jul 3. doi: 10.1016/j.isci.2023.107260
PMCID:
PMC10384225
AbstractArticlePDF–4.5M
13.
Influence of Age on Hyperoxia-Induced Cardiac Pathophysiology in Type 1 Diabetes Mellitus (T1DM) Mouse Model
Faizan Saleem, Hussein Mansour, Riddhi Vichare, Yashwant Ayalasomayajula, Jenna Yassine, Anagha Hesaraghatta, Siva Kumar Panguluri
Cells. 2023 Jun; 12(11): 1457. Published online 2023 May 24. doi: 10.3390/cells12111457
PMCID:
PMC10252211
AbstractArticlePDF–3.7M
14.
Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy
Valentina Dallacasagrande, Wei Liu, Dena Almeida, Min Luo, Katherine A. Hajjar
Invest Ophthalmol Vis Sci. 2023 Apr; 64(4): 33. Published online 2023 Apr 27. doi: 10.1167/iovs.64.4.33
PMCID:
PMC10150831
AbstractArticlePDF–9.3M
15.
USP7 controls NGN3 stability and pancreatic endocrine lineage development
Teodora Manea, Jessica Kristine Nelson, Cristina Maria Garrone, Karin Hansson, Ian Evans, Axel Behrens, Rocio Sancho
Nat Commun. 2023; 14: 2457. Published online 2023 Apr 28. doi: 10.1038/s41467-023-38146-9
PMCID:
PMC10147604
AbstractArticlePDF–9.0M
16.
Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition
Aviram Kogot-Levin, Yael Riahi, Ifat Abramovich, Ofri Mosenzon, Bella Agranovich, Liat Kadosh, Rachel Ben-Haroush Schyr, Doron Kleiman, Liad Hinden, Erol Cerasi, Danny Ben-Zvi, Ernesto Bernal-Mizrachi, Joseph Tam, Eyal Gottlieb, Gil Leibowitz
JCI Insight. 2023 Apr 10; 8(7): e164296. Published online 2023 Apr 10. doi: 10.1172/jci.insight.164296
PMCID:
PMC10132155
AbstractArticlePDF–9.1M
17.
DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity
Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan
Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506
Correction in:
Diabetes. 2023 Dec; 72(12): 1882.
PMCID:
PMC10130487
AbstractArticlePDF–1.8M
18.
Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia
Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon
iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500
PMCID:
PMC10121468
AbstractArticlePDF–12M
19.
MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas
Sara Bsharat, Emanuela Monni, Tania Singh, Jenny K. Johansson, Kavya Achanta, Ludivine Bertonnier-Brouty, Anja Schmidt-Christensen, Dan Holmberg, Zaal Kokaia, Rashmi B. Prasad, Isabella Artner
Development. 2023 Mar 15; 150(6): dev201009. Published online 2023 Mar 27. doi: 10.1242/dev.201009
PMCID:
PMC10112931
AbstractArticle
20.
Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling
Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister
Development. 2023 Jan 15; 150(2): dev201097. Published online 2023 Jan 16. doi: 10.1242/dev.201097
PMCID:
PMC10110501
AbstractArticle

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