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Select item 113490911.

Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target

Lu Lin, Shulin Huang, Xin Lin, Xiaoling Liu, Xiangjin Xu, Chunmei Li, Pin Chen

PLoS One. 2024; 19(8): e0309338. Published online 2024 Aug 27. doi: 10.1371/journal.pone.0309338

PMCID:: PMC11349091

Abstract Article PDF–4.3M

Select item 110913442.

Metrnl inhibits choroidal neovascularization by attenuating the choroidal inflammation via inactivating the UCHL-1/NF-κB signaling pathway

Lanyue Zhang, Youjian Li, Zhengyu Wu, Qiang Shen, Chunqin Zeng, Han Liu, Xuedong Zhang, Jiaxing Yang, Qiaoling Liu, Dianyong Tang, Kepeng Ou, Yanhong Fang

Front Immunol. 2024; 15: 1379586. Published online 2024 Apr 30. doi: 10.3389/fimmu.2024.1379586

PMCID:: PMC11091344

Abstract Article PDF–2.6M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106011604.

Meteorin-like/Meteorin-β protects LPS-induced acute lung injury by activating SIRT1-P53-SLC7A11 mediated ferroptosis pathway

Zhen Chen, Jun Li, Huan Peng, Mengli Zhang, Xian Wu, Feng Gui, Wei Li, Fen Ai, Bo Yu, Yijue Liu

Mol Med. 2023; 29: 144. Published online 2023 Oct 25. doi: 10.1186/s10020-023-00714-6

PMCID:: PMC10601160

Abstract Article PDF–3.0M

Select item 104919695.

Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy

Qing-Bo Lu, Yi Ding, Yao Liu, Zi-Chao Wang, Yu-Jie Wu, Kai-Ming Niu, Ke-Xue Li, Ji-Ru Zhang, Hai-Jian Sun

J Adv Res. 2023 Sep; 51: 161–179. Published online 2022 Nov 9. doi: 10.1016/j.jare.2022.10.014

PMCID:: PMC10491969

Abstract Article PDF–7.1M

Select item 101304896.

Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy

Yuxia Zhou, Lu Liu, Bangming Jin, Yixuan Wu, Lifen Xu, Xuebing Chang, Laying Hu, Guifang Wang, Yali Huang, Lingyu Song, Tian Zhang, Yuanyuan Wang, Ying Xiao, Fan Zhang, Mingjun Shi, Lingling Liu, Tuanlao Wang, Rui Yan, Bing Guo

Diabetes. 2023 May; 72(5): 611–626. Published online 2023 Feb 22. doi: 10.2337/db22-0680

PMCID:: PMC10130489

Abstract Article PDF–239M

Select item 100428437.

Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice

Chen Hong, Zhi Wang, Si-li Zheng, Wen-jun Hu, Shu-na Wang, Yan Zhao, Chao-yu Miao

Acta Pharmacol Sin. 2023 Apr; 44(4): 741–751. Published online 2022 Oct 13. doi: 10.1038/s41401-022-01009-y

PMCID:: PMC10042843

Abstract Article PDF–3.4M

Select item 98388788.

Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase

Marc R. Reboll, Stefanie Klede, Manuel H. Taft, Chen-Leng Cai, Loren J. Field, Kory J. Lavine, Andrew L. Koenig, Jenni Fleischauer, Johann Meyer, Axel Schambach, Hans W. Niessen, Maike Kosanke, Joop van den Heuvel, Andreas Pich, Johann Bauersachs, Xuekun Wu, Linqun Zheng, Yong Wang, Mortimer Korf-Klingebiel, Felix Polten, Kai C. Wollert

Science. Author manuscript; available in PMC 2023 Jun 17.

Published in final edited form as: Science. 2022 Jun 17; 376(6599): 1343–1347. Published online 2022 Jun 16. doi: 10.1126/science.abn3027

PMCID:: PMC9838878

Abstract Article PDF–1.3M

Select item 93091889.

The role of Meteorin‐like in skeletal development and bone fracture healing

Rong Huang, Abhinav R. Balu, Kristin H. Molitoris, James P. White, Alexander G. Robling, Ugur M. Ayturk, Gurpreet S. Baht

J Orthop Res. 2022 Nov; 40(11): 2510–2521. Published online 2022 Feb 8. doi: 10.1002/jor.25286

PMCID:: PMC9309188

Abstract Article PDF–3.6M

Select item 870072410.

Exercise Inhibits NLRP3 Inflammasome Activation in Obese Mice via the Anti-Inflammatory Effect of Meteorin-like

Hafiz Muhammad Ahmad Javaid, Namood E Sahar, De-Li ZhuGe, Joo Young Huh

Cells. 2021 Dec; 10(12): 3480. Published online 2021 Dec 9. doi: 10.3390/cells10123480

PMCID:: PMC8700724

Abstract Article PDF–35M

Select item 820361111.

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

Hélène Choquet, Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, 23andMe Research Team, Thomas J. Hoffmann, K. Saidas Nair, Pirro G. Hysi, Salil A. Lachke, Eric Jorgenson

Nat Commun. 2021; 12: 3595. Published online 2021 Jun 14. doi: 10.1038/s41467-021-23873-8

PMCID:: PMC8203611

Abstract Article PDF–1.9M

Select item 792369112.

Meteorin-like/Meteorin-β protects heart against cardiac dysfunction

Celia Rupérez, Gemma Ferrer-Curriu, Aina Cervera-Barea, Laura Florit, Mariona Guitart-Mampel, Gloria Garrabou, Mònica Zamora, Fàtima Crispi, Joaquim Fernandez-Solà, Josep Lupón, Antoni Bayes-Genis, Francesc Villarroya, Anna Planavila

J Exp Med. 2021 May 3; 218(5): e20201206. Published online 2021 Feb 26. doi: 10.1084/jem.20201206

PMCID:: PMC7923691

Abstract Article PDF–4.9M

Select item 750454513.

Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism

Gurpreet S. Baht, Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, Corey R. Hart, Jason R. Gibson, Ian R. Lanza, Virginia B. Kraus, Simon G. Gregory, Bruce M. Spiegelman, James P. White

Nat Metab. Author manuscript; available in PMC 2020 Sep 21.

Published in final edited form as: Nat Metab. 2020 Mar; 2(3): 278–289. Published online 2020 Mar 16. doi: 10.1038/s42255-020-0184-y

Correction in:: Nat Metab. 2020 Jul 14

PMCID:: PMC7504545

Abstract Article PDF–4.1M

Select item 747139514.

Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells

Sai-long Zhang, Zhi-yong Li, Dong-sheng Wang, Tian-ying Xu, Mao-bing Fan, Ming-he Cheng, Chao-yu Miao

Acta Pharmacol Sin. 2020 Jun; 41(6): 763–770. Published online 2020 Jan 16. doi: 10.1038/s41401-019-0343-4

PMCID:: PMC7471395

Abstract Article PDF–2.8M

Select item 738381615.

The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2

Jung Ok Lee, Won Seok Byun, Min Ju Kang, Jeong Ah Han, Jiyoung Moon, Min‐Jeong Shin, Ho Jun Lee, Ji Hyung Chung, Jin‐Seok Lee, Chang‐Gue Son, Kwon‐Ho Song, Tae Woo Kim, Eun‐Soo Lee, Hong Min Kim, Choon Hee Chung, Kevin R. W. Ngoei, Naomi X. Y. Ling, Jonathan S. Oakhill, Sandra Galic, Lisa Murray‐Segal, Bruce E. Kemp, Kyoung Min Kim, Soo Lim, Hyeon Soo Kim

FEBS J. 2020 May; 287(10): 2087–2104. Published online 2020 Apr 19. doi: 10.1111/febs.15301

PMCID:: PMC7383816

Abstract Article PDF–1.3M

Select item 649299416.

Subfatin is a Novel Adipokine and Unlike Meteorin in Adipose and Brain Expression

Zhi‐Yong Li, Si‐Li Zheng, Pei Wang, Tian‐Ying Xu, Yun‐Feng Guan, Yi‐Jie Zhang, Chao‐Yu Miao

CNS Neurosci Ther. 2014 Apr; 20(4): 344–354. Published online 2014 Jan 7. doi: 10.1111/cns.12219

PMCID:: PMC6492994

Abstract Article PDF–1015K

Select item 645951017.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 639485818.

Meteorin-like/Meteorin-Beta is a novel immunoregulatory cytokine associated with inflammation

Irina Ushach, Gerardo Arrevillaga-Boni, Gina N. Heller, Egest Pone, Marcela Hernandez, Jovani Catalan-Dibene, Peter Hevezi, Albert Zlotnik

J Immunol. Author manuscript; available in PMC 2019 Dec 15.

Published in final edited form as: J Immunol. 2018 Dec 15; 201(12): 3669–3676. Published online 2018 Nov 21. doi: 10.4049/jimmunol.1800435

PMCID:: PMC6394858

Abstract Article PDF–1.8M

Select item 613718719.

METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice

Tae Woo Jung, Sung Hoon Lee, Hyoung-Chun Kim, Joon Seok Bang, A. M. Abd El-Aty, Ahmet Hacımüftüoğlu, Yong Kyoo Shin, Ji Hoon Jeong

Exp Mol Med. 2018 Sep; 50(9): 122. Published online 2018 Sep 13. doi: 10.1038/s12276-018-0147-5

PMCID:: PMC6137187

Abstract Article PDF–1.6M

Select item 595256420.

Aerobic Exercise Increases Meteorin-Like Protein in Muscle and Adipose Tissue of Chronic High-Fat Diet-Induced Obese Mice

Ju Yong Bae

Biomed Res Int. 2018; 2018: 6283932. Published online 2018 Apr 30. doi: 10.1155/2018/6283932

PMCID:: PMC5952564

Abstract Article PDF–1010K

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