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Items: 1 to 20 of 37

1.
C5aR2 Deficiency Lessens C5aR1 Distribution and Expression in Neutrophils and Macrophages
Ting Zhang, Ning Ma, Jiaxing Wang, Xiaoyun Min, Linlin Wei, Ke Li
J Immunol Res. 2024; 2024: 2899154. Published online 2024 Jul 10. doi: 10.1155/2024/2899154
PMCID:
PMC11254461
AbstractArticlePDF–1.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita
Daniel L. Seiler, Katja H. Kähler, Marie Kleingarn, Christian D. Sadik, Katja Bieber, Jörg Köhl, Ralf J. Ludwig, Christian M. Karsten
Front Immunol. 2023; 14: 1197709. Published online 2023 May 19. doi: 10.3389/fimmu.2023.1197709
PMCID:
PMC10235453
AbstractArticlePDF–4.8M
4.
The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets
Henry Nording, Lasse Baron, David Haberthür, Frederic Emschermann, Matthias Mezger, Manuela Sauter, Reinhard Sauter, Johannes Patzelt, Kai Knoepp, Anne Nording, Moritz Meusel, Roza Meyer-Saraei, Ruslan Hlushchuk, Daniel Sedding, Oliver Borst, Ingo Eitel, Christian M. Karsten, Robert Feil, Bernd Pichler, Jeanette Erdmann, Admar Verschoor, Emmanouil Chavakis, Triantafyllos Chavakis, Philipp von Hundelshausen, Jörg Köhl, Meinrad Gawaz, Harald F. Langer
Nat Commun. 2021; 12: 3352. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23499-w
PMCID:
PMC8185003
AbstractArticlePDF–4.8M
5.
C3 Drives Inflammatory Skin Carcinogenesis Independently of C5
William D. Jackson, Alessandro Gulino, Liliane Fossati-Jimack, Rocio Castro Seoane, Kunyuan Tian, Katie Best, Jörg Köhl, Beatrice Belmonte, Jessica Strid, Marina Botto
J Invest Dermatol. 2021 Feb; 141(2): 404–414.e6. doi: 10.1016/j.jid.2020.06.025
PMCID:
PMC8150327
AbstractArticlePDF–4.5M
6.
Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock
Shinjini Chakraborty, Veronika Eva Winkelmann, Sonja Braumüller, Annette Palmer, Anke Schultze, Bettina Klohs, Anita Ignatius, Axel Vater, Michael Fauler, Manfred Frick, Markus Huber-Lang
Sci Rep. 2021; 11: 2158. Published online 2021 Jan 25. doi: 10.1038/s41598-020-79607-1
PMCID:
PMC7835219
AbstractArticlePDF–8.6M
7.
The C5a/C5aR2 axis promotes renal inflammation and tissue damage
Ting Zhang, Kun-yi Wu, Ning Ma, Ling-lin Wei, Malgorzata Garstka, Wuding Zhou, Ke Li
JCI Insight. 2020 Apr 9; 5(7): e134081. Published online 2020 Apr 9. doi: 10.1172/jci.insight.134081
PMCID:
PMC7205289
AbstractArticlePDF–34M
8.
The Second Receptor for C5a, C5aR2, is Detrimental to Mice during Systemic Infection with Listeria monocytogenes
Stacey L. Mueller-Ortiz, Pooja Shivshankar, Rick A. Wetsel
J Immunol. Author manuscript; available in PMC 2020 Nov 15.
Published in final edited form as: J Immunol. 2019 Nov 15; 203(10): 2701–2711. Published online 2019 Oct 9. doi: 10.4049/jimmunol.1900314
PMCID:
PMC6861014
AbstractArticlePDF–2.2M
9.
Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections
Marcel Muenstermann, Lea Strobel, Andreas Klos, Rick A. Wetsel, Trent M. Woodruff, Jörg Köhl, Kay O. Johswich
Virulence. 2019; 10(1): 677–694. Published online 2019 Jul 16. doi: 10.1080/21505594.2019.1640035
PMCID:
PMC6650196
AbstractArticlePDF–2.2M
10.
Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling
Chao Hu, Long Li, Peipei Ding, Ling Li, Xiaowen Ge, Long Zheng, Xuanchuan Wang, Jina Wang, Weitao Zhang, Na Wang, Hongyu Gu, Fan Zhong, Ming Xu, Ruiming Rong, Tongyu Zhu, Weiguo Hu
J Immunol. 2018 Dec 15; 201(12): 3717–3730. Published online 2018 Nov 14. doi: 10.4049/jimmunol.1800987
PMCID:
PMC6287101
AbstractArticlePDF–3.6M
11.
T cell expression of C5a receptor 2 augments murine regulatory T cell generation and regulatory-T-cell-dependent cardiac allograft survival
Divya Verghese, Markus Demir, Nicholas Chun, Miguel Fribourg, Paolo Cravedi, Ines Llaudo, Trent M. Woodruff, Pragya Yadav, Sergio A. Lira, M. Edward Medof, Peter S. Heeger
J Immunol. Author manuscript; available in PMC 2019 Mar 15.
Published in final edited form as: J Immunol. 2018 Mar 15; 200(6): 2186–2198. Published online 2018 Feb 7. doi: 10.4049/jimmunol.1701638
PMCID:
PMC5894525
AbstractArticlePDF–3.1M
12.
Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2
Christian M. Karsten, Tina Beckmann, Maike M. Holtsche, Jenny Tillmann, Sabrina Tofern, Franziska S. Schulze, Eva Nina Heppe, Ralf J. Ludwig, Detlef Zillikens, Inke R. König, Jörg Köhl, Enno Schmidt
Front Immunol. 2018; 9: 488. Published online 2018 Mar 15. doi: 10.3389/fimmu.2018.00488
PMCID:
PMC5862877
AbstractArticlePDF–4.0M
13.
Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair
Anna Kovtun, Stephanie Bergdolt, Yvonne Hägele, Rebekka Matthes, John D. Lambris, Markus Huber-Lang, Anita Ignatius
Sci Rep. 2017; 7: 14061. Published online 2017 Oct 25. doi: 10.1038/s41598-017-14444-3
PMCID:
PMC5656620
AbstractArticlePDF–6.3M
14.
Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction
Fatemeh Fattahi, Miriam Kalbitz, Elizabeth A. Malan, Elizabeth Abe, Lawrence Jajou, Markus S. Huber-Lang, Markus Bosmann, Mark W. Russell, Firas S. Zetoune, Peter A. Ward
FASEB J. 2017 Sep; 31(9): 4129–4139. Published online 2017 Jun 1. doi: 10.1096/fj.201700140R
PMCID:
PMC5572692
AbstractArticle
15.
C5L2, the Second C5a Anaphylatoxin Receptor, Suppresses LPS-Induced Acute Lung Injury
Ruobing Wang, Bao Lu, Craig Gerard, Norma P. Gerard
Am J Respir Cell Mol Biol. 2016 Nov; 55(5): 657–666. doi: 10.1165/rcmb.2016-0067OC
PMCID:
PMC5105183
AbstractArticlePDF–1.2M
16.
Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis
Miriam Kalbitz, Fatemeh Fattahi, Jamison J. Grailer, Lawrence Jajou, Elizabeth A. Malan, Firas S. Zetoune, Markus Huber-Lang, Mark W. Russell, Peter A. Ward
FASEB J. 2016 Dec; 30(12): 3997–4006. Published online 2016 Aug 19. doi: 10.1096/fj.201600728R
PMCID:
PMC5102118
AbstractArticle
17.
Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis
Ruobing Wang, Bao Lu, Craig Gerard, Norma P. Gerard
J Immunol. Author manuscript; available in PMC 2015 Aug 27.
Published in final edited form as: J Immunol. 2013 Oct 15; 191(8): 4001–4009. Published online 2013 Sep 16. doi: 10.4049/jimmunol.1301626
PMCID:
PMC4551435
AbstractArticlePDF–640K
18.
Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia
Hiroko Nomaru, Kunihiko Sakumi, Atsuhisa Katogi, Yoshinori N Ohnishi, Kosuke Kajitani, Daisuke Tsuchimoto, Eric J. Nestler, Yusaku Nakabeppu
Glia. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Glia. 2014 Aug; 62(8): 1284–1298. Published online 2014 Apr 25. doi: 10.1002/glia.22680
PMCID:
PMC4090226
AbstractArticlePDF–954K
19.
Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria
Hani Kim, Laura K. Erdman, Ziyue Lu, Lena Serghides, Kathleen Zhong, Aggrey Dhabangi, Charles Musoke, Craig Gerard, Christine Cserti-Gazdewich, W. Conrad Liles, Kevin C. Kain
Infect Immun. 2014 Jan; 82(1): 371–379. doi: 10.1128/IAI.01246-13
PMCID:
PMC3911851
AbstractArticlePDF–818K
20.
C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN
Hong Xiao, Daniel J. Dairaghi, Jay P. Powers, Linda S. Ertl, Trageen Baumgart, Yu Wang, Lisa C. Seitz, Mark E.T. Penfold, Lin Gan, Peiqi Hu, Bao Lu, Norma P. Gerard, Craig Gerard, Thomas J. Schall, Juan C. Jaen, Ronald J. Falk, J. Charles Jennette
J Am Soc Nephrol. 2014 Feb; 25(2): 225–231. Published online 2013 Oct 31. doi: 10.1681/ASN.2013020143
PMCID:
PMC3904560
AbstractArticle

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