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Select item 113720931.

Finely ordered intracellular domain harbors an allosteric site to modulate physiopathological function of P2X3 receptors

Yi-Yu Lin, Yan Lu, Chun-Yun Li, Xue-Fei Ma, Miao-Qing Shao, Yu-Hao Gao, Yu-Qing Zhang, Hai-Ning Jiang, Yan Liu, Yang Yang, Li-Dong Huang, Peng Cao, Heng-Shan Wang, Jin Wang, Ye Yu

Nat Commun. 2024; 15: 7652. Published online 2024 Sep 3. doi: 10.1038/s41467-024-51815-7

PMCID:: PMC11372093

Abstract Article PDF–3.2M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 95227963.

Spontaneous activity in whisker-innervating region of neonatal mouse trigeminal ganglion

Piu Banerjee, Fumi Kubo, Hirofumi Nakaoka, Rieko Ajima, Takuya Sato, Tatsumi Hirata, Takuji Iwasato

Sci Rep. 2022; 12: 16311. Published online 2022 Sep 29. doi: 10.1038/s41598-022-20068-z

PMCID:: PMC9522796

Abstract Article PDF–9.5M

Select item 81997924.

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30

Peter Illes, Christa E. Müller, Kenneth A. Jacobson, Thomas Grutter, Annette Nicke, Samuel J. Fountain, Charles Kennedy, Günther Schmalzing, Michael F. Jarvis, Stanko S. Stojilkovic, Brian F. King, Francesco Di Virgilio

Br J Pharmacol. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Br J Pharmacol. 2021 Feb; 178(3): 489–514. Published online 2020 Dec 21. doi: 10.1111/bph.15299

PMCID:: PMC8199792

Abstract Article PDF–1.7M

Select item 77952695.

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing

Ruirui Lu, Katharina Metzner, Fangyuan Zhou, Cathrin Flauaus, Annika Balzulat, Patrick Engel, Jonas Petersen, Rebekka Ehinger, Anne Bausch, Peter Ruth, Robert Lukowski, Achim Schmidtko

Int J Mol Sci. 2021 Jan; 22(1): 405. Published online 2021 Jan 2. doi: 10.3390/ijms22010405

PMCID:: PMC7795269

Abstract Article PDF–2.8M

Select item 77130766.

Bladder urothelium converts bacterial lipopolysaccharide information into neural signaling via an ATP-mediated pathway to enhance the micturition reflex for rapid defense

Norichika Ueda, Makoto Kondo, Kentaro Takezawa, Hiroshi Kiuchi, Yosuke Sekii, Yusuke Inagaki, Tetsuji Soda, Shinichiro Fukuhara, Kazutoshi Fujita, Motohide Uemura, Ryoichi Imamura, Yasushi Miyagawa, Norio Nonomura, Shoichi Shimada

Sci Rep. 2020; 10: 21167. Published online 2020 Dec 3. doi: 10.1038/s41598-020-78398-9

PMCID:: PMC7713076

Abstract Article PDF–13M

Select item 74739117.

Sugar causes obesity and metabolic syndrome in mice independently of sweet taste

Ana Andres-Hernando, Masanari Kuwabara, David J. Orlicky, Aurelie Vandenbeuch, Christina Cicerchi, Sue C. Kinnamon, Thomas E. Finger, Richard J. Johnson, Miguel A. Lanaspa

Am J Physiol Endocrinol Metab. 2020 Aug 1; 319(2): E276–E290. Published online 2020 Jun 23. doi: 10.1152/ajpendo.00529.2019

PMCID:: PMC7473911

Abstract Article

Select item 74185338.

The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development

Zhirong Wang, Johnny S. Jung, Talya C. Inbar, Katherine M. Rangoussis, Christian Faaborg-Andersen, Thomas M. Coate

eNeuro. 2020 Jul-Aug; 7(4): ENEURO.0179-20.2020. Prepublished online 2020 Jul 16. Published online 2020 Aug 7. doi: 10.1523/ENEURO.0179-20.2020

PMCID:: PMC7418533

Abstract Article PDF–9.2M

Select item 67626539.

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP

Mila Vlaskovska, Lubomir Kasakov, Weifang Rong, Philippe Bodin, Michelle Bardini, Debra A. Cockayne, Anthony P. D. W. Ford, Geoffrey Burnstock

J Neurosci. 2001 Aug 1; 21(15): 5670–5677. doi: 10.1523/JNEUROSCI.21-15-05670.2001

PMCID:: PMC6762653

Abstract Article PDF–754K

Select item 674051410.

Pivotal Role of Nucleotide P2X₂ Receptor Subunit of the ATP-Gated Ion Channel Mediating Ventilatory Responses to Hypoxia

Weifang Rong, Alexander V. Gourine, Debra A. Cockayne, Zhenghua Xiang, Anthony P. D. W. Ford, K. Michael Spyer, Geoffrey Burnstock

J Neurosci. 2003 Dec 10; 23(36): 11315–11321. doi: 10.1523/JNEUROSCI.23-36-11315.2003

PMCID:: PMC6740514

Abstract Article PDF–456K

Select item 673041311.

Essential Function of Oncostatin M in Nociceptive Neurons of Dorsal Root Ganglia

Yoshihiro Morikawa, Shinobu Tamura, Ken-ichi Minehata, Peter J. Donovan, Atsushi Miyajima, Emiko Senba

J Neurosci. 2004 Feb 25; 24(8): 1941–1947. doi: 10.1523/JNEUROSCI.4975-03.2004

PMCID:: PMC6730413

Abstract Article PDF–534K

Select item 668750612.

ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons

An-Jing Ren, Kai Wang, Huan Zhang, Anjun Liu, Xianhua Ma, Qing Liang, Dongmei Cao, John N. Wood, David Z. He, Yu-Qiang Ding, Wen-Jun Yuan, Zhifang Xie, Weiping J. Zhang

Nat Commun. Author manuscript; available in PMC 2019 Aug 8.

Published in final edited form as: Nat Commun. 2014 Nov 5; 5: 4984. Published online 2014 Nov 5. doi: 10.1038/ncomms5984

PMCID:: PMC6687506

Abstract Article PDF–3.4M

Select item 607721113.

Fast Ca²⁺ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca²⁺ Waves of Inner Supporting Cells in the Developing Mouse Cochlea

Tobias Eckrich, Kerstin Blum, Ivan Milenkovic, Jutta Engel

Front Mol Neurosci. 2018; 11: 264. Published online 2018 Jul 30. doi: 10.3389/fnmol.2018.00264

PMCID:: PMC6077211

Abstract Article PDF–7.4M

Select item 577696314.

Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification

Christopher R. Donnelly, Amol A. Shah, Charlotte M. Mistretta, Robert M. Bradley, Brian A. Pierchala

Proc Natl Acad Sci U S A. 2018 Jan 16; 115(3): E516–E525. Published online 2017 Dec 27. doi: 10.1073/pnas.1708838115

PMCID:: PMC5776963

Abstract Article PDF–2.4M

Select item 540707615.

Glucose elicits cephalic-phase insulin release in mice by activating K_ATP channels in taste cells

John I. Glendinning, Yonina G. Frim, Ayelet Hochman, Gabrielle S. Lubitz, Anthony J. Basile, Anthony Sclafani

Am J Physiol Regul Integr Comp Physiol. 2017 Apr 1; 312(4): R597–R610. Published online 2017 Jan 27. doi: 10.1152/ajpregu.00433.2016

PMCID:: PMC5407076

Abstract Article

Select item 513814916.

Immunocytochemical Organization and Sour Taste Activation in the Rostral Nuc. Solitary Tract of Mice

Jennifer M. Stratford, John A. Thompson, Thomas E. Finger

J Comp Neurol. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: J Comp Neurol. 2017 Feb 1; 525(2): 271–290. Published online 2016 Aug 11. doi: 10.1002/cne.24059

PMCID:: PMC5138149

Abstract Article PDF–4.9M

Select item 495599917.

Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine

Anna Marchenkova, Sandra Vilotti, Niels Ntamati, Arn MJM van den Maagdenberg, Andrea Nistri

Mol Pain. 2016; 12: 1744806916646110. Published online 2016 May 12. doi: 10.1177/1744806916646110

PMCID:: PMC4955999

Abstract Article PDF–978K

Select item 482002118.

Altered expression of P2X₃ in vagal and spinal afferents following esophagitis in rats

Banani Banerjee, Bidyut K. Medda, Jamie Schmidt, Yue Zheng, Zhihong Zhang, Reza Shaker, Jyoti N. Sengupta

Histochem Cell Biol. Author manuscript; available in PMC 2016 Apr 4.

Published in final edited form as: Histochem Cell Biol. 2009 Dec; 132(6): 585–597. Published online 2009 Sep 26. doi: 10.1007/s00418-009-0639-4

PMCID:: PMC4820021

Abstract Article PDF–3.1M

Select item 465094319.

Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization

Anna Marchenkova, Sandra Vilotti, Elsa Fabbretti, Andrea Nistri

Mol Pain. 2015; 11: 71. Published online 2015 Nov 14. doi: 10.1186/s12990-015-0074-6

PMCID:: PMC4650943

Abstract Article PDF–3.1M

Select item 438100320.

Incoherent Feed-Forward Regulatory Loops Control Segregation of C-Mechanoreceptors, Nociceptors, and Pruriceptors

Shan Lou, Xiaoxin Pan, Tianwen Huang, Bo Duan, Fu-Chia Yang, Juan Yang, Mulin Xiong, Yang Liu, Qiufu Ma

J Neurosci. 2015 Apr 1; 35(13): 5317–5329. doi: 10.1523/JNEUROSCI.0122-15.2015

PMCID:: PMC4381003

Abstract Article PDF–4.4M

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