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Select item 111433281.

Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum

Ting-Feng Lin, Silas E. Busch, Christian Hansel

Nat Commun. 2024; 15: 4645. Published online 2024 May 31. doi: 10.1038/s41467-024-48373-3

PMCID:: PMC11143328

Abstract Article PDF–5.0M

Select item 109381242.

ROS in diabetic atria regulate SK2 degradation by Atrogin-1 through the NF-κB signaling pathway

Jian Xu, Dong Zhang, Yibo Ma, Hui Du, Yi Wang, Wenping Luo, Ruxing Wang, Fu Yi

J Biol Chem. 2024 Mar; 300(3): 105735. Published online 2024 Feb 8. doi: 10.1016/j.jbc.2024.105735

PMCID:: PMC10938124

Abstract Article PDF–3.6M

Select item 108053973.

MPP2 interacts with SK2 to rescue the excitability of glutamatergic neurons in the BLA and facilitate the extinction of conditioned fear in mice

Xiaohan Peng, Panpan Chen, Yang Zhang, Ke Wu, Ningning Ji, Jinghua Gao, Hui Wang, Yong‐mei Zhang, Tie Xu, Rong Hua

CNS Neurosci Ther. 2024 Jan; 30(1): e14362. Published online 2023 Jul 19. doi: 10.1111/cns.14362

PMCID:: PMC10805397

Abstract Article PDF–16M

Select item 75281314.

Predisposition of Neonatal Maternal Separation to Visceral Hypersensitivity via Downregulation of Small-Conductance Calcium-Activated Potassium Channel Subtype 2 (SK2) in Mice

Ke Wu, Jing-hua Gao, Rong Hua, Xiao-han Peng, Hui Wang, Yong-mei Zhang

Neural Plast. 2020; 2020: 8876230. Published online 2020 Sep 22. doi: 10.1155/2020/8876230

PMCID:: PMC7528131

Abstract Article PDF–3.7M

Select item 72999665.

PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome

Jiandong Sun, Yan Liu, Guoqi Zhu, Caleb Cato, Xiaoning Hao, Li Qian, Weiju Lin, Rachana Adhikari, Yun Luo, Michel Baudry, Xiaoning Bi

Sci Rep. 2020; 10: 9824. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66790-4

PMCID:: PMC7299966

Abstract Article PDF–9.7M

Select item 72944546.

Muscarinic Modulation of SK2-Type K⁺ Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex

Daniel F. Gill, Christian Hansel

eNeuro. 2020 Mar-Apr; 7(2): ENEURO.0453-19.2020. Prepublished online 2020 Jan 30. Published online 2020 Mar 4. doi: 10.1523/ENEURO.0453-19.2020

PMCID:: PMC7294454

Abstract Article PDF–1.7M

Select item 69649167.

SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces

Giorgio Grasselli, Henk-Jan Boele, Heather K. Titley, Nora Bradford, Lisa van Beers, Lindsey Jay, Gerco C. Beekhof, Silas E. Busch, Chris I. De Zeeuw, Martijn Schonewille, Christian Hansel

PLoS Biol. 2020 Jan; 18(1): e3000596. Published online 2020 Jan 6. doi: 10.1371/journal.pbio.3000596

PMCID:: PMC6964916

Abstract Article PDF–3.4M

Select item 67936418.

Small-Conductance Ca²⁺-Activated K⁺ Channel Type 2 (SK2) Modulates Hippocampal Learning, Memory, and Synaptic Plasticity

Rebecca S. Hammond, Chris T. Bond, Timothy Strassmaier, Thu Jennifer Ngo-Anh, John P. Adelman, James Maylie, Robert W. Stackman

J Neurosci. 2006 Feb 8; 26(6): 1844–1853. doi: 10.1523/JNEUROSCI.4106-05.2006

Correction in:: J Neurosci. 2006 Apr 26; 26(17): 4714.

PMCID:: PMC6793641

Abstract Article PDF–683K

Select item 66084199.

Coassembly and Coupling of SK2 Channels and mGlu₅ Receptors

Gloria García-Negredo, David Soto, Javier Llorente, Xavier Morató, Koen M.O. Galenkamp, Maricel Gómez-Soler, Víctor Fernández-Dueñas, Masahiko Watanabe, John P. Adelman, Ryuichi Shigemoto, Yugo Fukazawa, Rafael Luján, Francisco Ciruela

J Neurosci. 2014 Oct 29; 34(44): 14793–14802. doi: 10.1523/JNEUROSCI.2038-14.2014

PMCID:: PMC6608419

Abstract Article PDF–2.6M

Select item 642207310.

F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria

Tian-You Ling, Fu Yi, Tong Lu, Xiao-Li Wang, Xiaojing Sun, Monte S. Willis, Li-Qun Wu, Win-Kuang Shen, John P. Adelman, Hon-Chi Lee

J Biol Chem. 2019 Mar 15; 294(11): 4160–4168. Published online 2019 Jan 11. doi: 10.1074/jbc.RA118.003837

PMCID:: PMC6422073

Abstract Article PDF–2.2M

Select item 625154111.

Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease

Jose F. Moruno-Manchon, Ndidi-Ese Uzor, Maria P. Blasco-Conesa, Sishira Mannuru, Nagireddy Putluri, Erin E. Furr-Stimming, Andrey S. Tsvetkov

Hum Mol Genet. 2017 Apr 1; 26(7): 1305–1317. Published online 2017 Feb 8. doi: 10.1093/hmg/ddx046

PMCID:: PMC6251541

Abstract Article PDF–752K

Select item 615637912.

SK2 Channels Associate With mGlu_1α Receptors and Ca_V2.1 Channels in Purkinje Cells

Rafael Luján, Carolina Aguado, Francisco Ciruela, Xavier Morató Arus, Alejandro Martín-Belmonte, Rocío Alfaro-Ruiz, Jesús Martínez-Gómez, Luis de la Ossa, Masahiko Watanabe, John P. Adelman, Ryuichi Shigemoto, Yugo Fukazawa

Front Cell Neurosci. 2018; 12: 311. Published online 2018 Sep 19. doi: 10.3389/fncel.2018.00311

PMCID:: PMC6156379

Abstract Article PDF–6.5M

Select item 608429513.

Functional interaction of Junctophilin 2 with small‐ conductance Ca²⁺‐activated potassium channel subtype 2(SK2) in mouse cardiac myocytes

H. K. Fan, T. X. Luo, W. D. Zhao, Y. H. Mu, Y. Yang, W. J. Guo, H. Y. Tu, Q. Zhang

Acta Physiol (Oxf) 2018 Mar; 222(3): e12986. Published online 2017 Dec 7. doi: 10.1111/apha.12986

PMCID:: PMC6084295

Abstract Article PDF–2.2M

Select item 542311114.

SK2 channels regulate mitochondrial respiration and mitochondrial Ca²⁺ uptake

Birgit Honrath, Lina Matschke, Tammo Meyer, Lena Magerhans, Fabiana Perocchi, Goutham K Ganjam, Hans Zischka, Cornelius Krasel, Albert Gerding, Barbara M Bakker, Moritz Bünemann, Stefan Strack, Niels Decher, Carsten Culmsee, Amalia M Dolga

Cell Death Differ. 2017 May; 24(5): 761–773. Published online 2017 Mar 10. doi: 10.1038/cdd.2017.2

PMCID:: PMC5423111

Abstract Article PDF–3.6M

Select item 511988515.

Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

Derya Sargin, David K Oliver, Evelyn K Lambe

eLife. 2016; 5: e21416. Published online 2016 Nov 22. doi: 10.7554/eLife.21416

PMCID:: PMC5119885

Abstract Article PDF–1.6M

Select item 480549716.

Activity-dependent plasticity of spike pauses in cerebellar Purkinje cells

Giorgio Grasselli, Qionger He, Vivian Wan, John P. Adelman, Gen Ohtsuki, Christian Hansel

Cell Rep. Author manuscript; available in PMC 2016 Mar 23.

Published in final edited form as: Cell Rep. 2016 Mar 22; 14(11): 2546–2553. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.054

PMCID:: PMC4805497

Abstract Article PDF–1.2M

Select item 476456417.

Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

Gukhan Kim, Rafael Luján, Jochen Schwenk, Melissa H Kelley, Carolina Aguado, Masahiko Watanabe, Bernd Fakler, James Maylie, John P Adelman

eLife. 2016; 5: e12637. Published online 2016 Feb 12. doi: 10.7554/eLife.12637

PMCID:: PMC4764564

Abstract Article PDF–2.8M

Select item 473729618.

Knockdown of the small conductance Ca²⁺‐activated K⁺ channels is potently cytotoxic in breast cancer cell lines

Zana Azeez Abdulkareem, Julia MW Gee, Charles D Cox, Kenneth T Wann

Br J Pharmacol. 2016 Jan; 173(1): 177–190. Published online 2015 Dec 5. doi: 10.1111/bph.13357

PMCID:: PMC4737296

Abstract Article PDF–1.8M

Select item 452070319.

UBE3A regulates synaptic plasticity and learning and memory by controlling SK2 channel endocytosis

Jiandong Sun, Guoqi Zhu, Yan Liu, Steve Standley, Angela Ji, Rashmi Tunuguntla, Yubin Wang, Chad Claus, Lyna Luo, Michel Baudry, Xiaoning Bi

Cell Rep. Author manuscript; available in PMC 2016 Jul 21.

Published in final edited form as: Cell Rep. 2015 Jul 21; 12(3): 449–461. Published online 2015 Jul 9. doi: 10.1016/j.celrep.2015.06.023

PMCID:: PMC4520703

Abstract Article PDF–2.2M

Select item 448439220.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Abstract Article PDF–604K

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