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Select item 111905791.

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation

Robin E. Kruger, Tristan Frum, A. Sophie Brumm, Stephanie L. Hickey, Kathy K. Niakan, Farina Aziz, Marcelio A. Shammami, Jada G. Roberts, Amy Ralston

Development. 2024 Jun 1; 151(11): dev202377. Published online 2024 Jun 5. doi: 10.1242/dev.202377

PMCID:: PMC11190579

Abstract Article

Select item 110743122.

The transcription factor OCT6 promotes the dissolution of the naïve pluripotent state by repressing Nanog and activating a formative state gene regulatory network

Ariel Waisman, Federico Sevlever, Denisse Saulnier, Marcos Francia, Renata Blanco, Guadalupe Amín, Antonella Lombardi, Celeste Biani, María Belén Palma, Agustina Scarafía, Joaquín Smucler, Alejandro La Greca, Lucía Moro, Gustavo Sevlever, Alejandra Guberman, Santiago Miriuka

Sci Rep. 2024; 14: 10420. Published online 2024 May 7. doi: 10.1038/s41598-024-59247-5

PMCID:: PMC11074312

Abstract Article PDF–5.8M

Select item 108078153.

Endogenous retroviruses shape pluripotency specification in mouse embryos

Sergio de la Rosa, María del Mar Rigual, Pierfrancesco Vargiu, Sagrario Ortega, Nabil Djouder

Sci Adv. 2024 Jan 26; 10(4): eadk9394. Published online 2024 Jan 24. doi: 10.1126/sciadv.adk9394

PMCID:: PMC10807815

Abstract Article PDF–23M

Select item 107582924.

Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness

Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C. Tobias, Sakthi D. Moorthy, Ryan K. Dale, Jennifer A. Mitchell, Timothy J. Petros, Pedro P. Rocha

Nat Genet. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Nat Genet. 2023 Feb; 55(2): 280–290. Published online 2023 Jan 30. doi: 10.1038/s41588-022-01295-6

PMCID:: PMC10758292

Abstract Article PDF–4.9M

Select item 106541015.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 106003416.

STRA8–RB interaction is required for timely entry of meiosis in mouse female germ cells

Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro

Nat Commun. 2023; 14: 6443. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42259-6

PMCID:: PMC10600341

Abstract Article PDF–12M

Select item 103871297.

RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation

Di Wu, Jurrien Dean

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112047. Published online 2023 Jan 30. doi: 10.1016/j.celrep.2023.112047

PMCID:: PMC10387129

Abstract Article PDF–2.2M

Select item 103589678.

Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo

Marcelo D. Goissis, Brian Bradshaw, Eszter Posfai, Janet Rossant

PLoS One. 2023; 18(7): e0279515. Published online 2023 Jul 20. doi: 10.1371/journal.pone.0279515

PMCID:: PMC10358967

Abstract Article PDF–1.5M

Select item 102778249.

Embryonic stem cell ERK, AKT, plus STAT3 response dynamics combinatorics are heterogeneous but NANOG state independent

Andreas Reimann, Tobias Kull, Weijia Wang, Philip Dettinger, Dirk Loeffler, Timm Schroeder

Stem Cell Reports. 2023 Jun 13; 18(6): 1295–1307. Published online 2023 May 18. doi: 10.1016/j.stemcr.2023.04.008

PMCID:: PMC10277824

Abstract Article PDF–4.7M

Select item 1026758810.

Involvement of linker histone variant H1a in the regulation of early preimplantation development in mice

Satoshi FUNAYA, Yuan WANG, Masataka G. SUZUKI, Masahito IKAWA, Fugaku AOKI

J Reprod Dev. 2023 Jun; 69(3): 178–182. Published online 2023 Apr 17. doi: 10.1262/jrd.2023-013

PMCID:: PMC10267588

Abstract Article PDF–1.5M

Select item 1024437711.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

Aditya Kshirsagar, Svetlana Maslov Doroshev, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob H. Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner

Nat Commun. 2023; 14: 3293. Published online 2023 Jun 6. doi: 10.1038/s41467-023-38797-8

PMCID:: PMC10244377

Abstract Article PDF–8.5M

Select item 998453412.

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero, Annekatrien Boel, Sofia Papanikolaou, Bernard K. van der Veer, Adrian Janiszewski, Tijs Vanhessche, Annick Francis, Youssef El Laithy, Antonio Lo Nigro, Francesco Aulicino, Kian Peng Koh, Vincent Pasque, Maria Pia Cosma, Catherine Verfaillie, An Zwijsen, Björn Heindryckx, Christoforos Nikolaou, Frederic Lluis

Nat Commun. 2023; 14: 1210. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36914-1

PMCID:: PMC9984534

Abstract Article PDF–3.7M

Select item 988411913.

Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro

Sophie Kraunsoe, Takuya Azami, Yihan Pei, Graziano Martello, Kenneth Jones, Thorsten Boroviak, Jennifer Nichols

Biol Open. 2023 Jan 1; 12(1): bio059650. Published online 2023 Jan 17. doi: 10.1242/bio.059650

PMCID:: PMC9884119

Abstract Article PDF–3.5M

Select item 968706514.

Progression of the pluripotent epiblast depends upon the NMD factor UPF2

Jennifer N. Chousal, Abhishek Sohni, Kristoffer Vitting-Seerup, Kyucheol Cho, Matthew Kim, Kun Tan, Bo Porse, Miles F. Wilkinson, Heidi Cook-Andersen

Development. 2022 Nov 1; 149(21): dev200764. Published online 2022 Nov 7. doi: 10.1242/dev.200764

Correction in:: Development. 2024 Jun 15; 151(12): dev203145.

PMCID:: PMC9687065

Abstract Article

Select item 953477215.

Embryo model completes gastrulation to neurulation and organogenesis

Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz

Nature. 2022; 610(7930): 143–153. Published online 2022 Aug 25. doi: 10.1038/s41586-022-05246-3

PMCID:: PMC9534772

Abstract Article PDF–29M

Select item 953441316.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 951514417.

Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos

Marta Czernik, Dawid Winiarczyk, Silvestre Sampino, Paweł Gręda, Salvatore Parillo, Jacek Andrzej Modliński, Pasqualino Loi

Sci Rep. 2022; 12: 16152. Published online 2022 Sep 27. doi: 10.1038/s41598-022-20374-6

Correction in:: Sci Rep. 2022; 12: 21276.

PMCID:: PMC9515144

Abstract Article PDF–1.6M

Select item 948233318.

H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate

Agnès Dubois, Loris Vincenti, Almira Chervova, Maxim V. C. Greenberg, Sandrine Vandormael-Pournin, Déborah Bourc'his, Michel Cohen-Tannoudji, Pablo Navarro

Development. 2022 Sep 1; 149(17): dev201074. Published online 2022 Sep 9. doi: 10.1242/dev.201074

PMCID:: PMC9482333

Abstract Article

Select item 948085619.

RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription

Abderhman Abuhashem, Alexandra G. Chivu, Yixin Zhao, Edward J. Rice, Adam Siepel, Charles G. Danko, Anna-Katerina Hadjantonakis

Genes Dev. 2022 Jul 1; 36(13-14): 770–789. doi: 10.1101/gad.349565.122

PMCID:: PMC9480856

Abstract Article PDF–11M

Select item 938175720.

H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst

Mélanie Pailles, Mélanie Hirlemann, Vincent Brochard, Martine Chebrout, Jean-François Oudin, Hendrik Marks, Alice Jouneau, Amélie Bonnet-Garnier

Sci Rep. 2022; 12: 13908. Published online 2022 Aug 16. doi: 10.1038/s41598-022-17730-x

PMCID:: PMC9381757

Abstract Article PDF–4.6M

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