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Items: 1 to 20 of 22

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice
Gaozan Tong, Yiming Chen, Xixi Chen, Junfu Fan, Kunxuan Zhu, ZiJing Hu, Santie Li, Junjie Zhu, Jianjun Feng, Zhaohang Wu, Zhenyu Hu, Bin Zhou, Litai Jin, Hui Chen, Jingling Shen, Weitao Cong, XiaoKun Li
Nat Commun. 2023; 14: 6107. Published online 2023 Sep 30. doi: 10.1038/s41467-023-41800-x
PMCID:
PMC10542385
AbstractArticlePDF–8.4M
3.
Deubiquitinase USP16 induces gouty arthritis via Drp1-dependent mitochondrial fission and NLRP3 inflammasome activation
Qingdong Wang, Hongbin Qiu
Arthritis Res Ther. 2023; 25: 126. Published online 2023 Jul 24. doi: 10.1186/s13075-023-03095-7
PMCID:
PMC10367261
AbstractArticlePDF–13M
4.
USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation
Yan Rong, Ye-Zhang Zhu, Jia-li Yu, Yun-Wen Wu, Shu-Yan Ji, Yong Zhou, Yu Jiang, Jin Jin, Heng-Yu Fan, Li Shen, Qian-Qian Sha
Nucleic Acids Res. 2022 Jun 10; 50(10): 5599–5616. Published online 2022 May 30. doi: 10.1093/nar/gkac468
PMCID:
PMC9178006
AbstractArticlePDF–6.6M
5.
Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model
Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
eLife. 2022; 11: e66037. Published online 2022 Mar 21. doi: 10.7554/eLife.66037
PMCID:
PMC9122497
AbstractArticlePDF–6.4M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance
Yu Zhang, Rong-bei Liu, Qian Cao, Ke-qi Fan, Ling-jie Huang, Jian-shuai Yu, Zheng-jun Gao, Tao Huang, Jiang-yan Zhong, Xin-tao Mao, Fei Wang, Peng Xiao, Yuan Zhao, Xin-hua Feng, Yi-yuan Li, Jin Jin
J Clin Invest. 2019 Jul 1; 129(7): 2856–2871. Published online 2019 May 28. doi: 10.1172/JCI123801
PMCID:
PMC6597231
AbstractArticlePDF–11M
8.
Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation
Maddalena Adorno, Benedetta Nicolis di Robilant, Shaheen Shabbir Sikandar, Veronica Haro Acosta, Jane Antony, Craig H. Heller, Michael F. Clarke
Sci Rep. 2018; 8: 17506. Published online 2018 Nov 30. doi: 10.1038/s41598-018-34562-w
PMCID:
PMC6269430
AbstractArticlePDF–1.7M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome
Faycal Guedj, Jeroen LA Pennings, Lauren J. Massingham, Heather C. Wick, Ashley E. Siegel, Umadevi Tantravahi, Diana W. Bianchi
Sci Rep. 2016; 6: 32353. Published online 2016 Sep 2. doi: 10.1038/srep32353
PMCID:
PMC5009456
AbstractArticlePDF–1.2M
11.
Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression
Lori Borgal, Markus M. Rinschen, Claudia Dafinger, Valérie I. Liebrecht, Hinrich Abken, Thomas Benzing, Bernhard Schermer
Cell Cycle. 2016; 15(8): 1034–1045. Published online 2016 Feb 26. doi: 10.1080/15384101.2016.1152429
PMCID:
PMC4889251
AbstractArticlePDF–1.1M
12.
The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function
Yue Gu, Amanda E. Jones, Wei Yang, Shanrun Liu, Qian Dai, Yudong Liu, C. Scott Swindle, Dewang Zhou, Zhuo Zhang, Thomas M. Ryan, Tim M. Townes, Christopher A. Klug, Dongquan Chen, Hengbin Wang
Proc Natl Acad Sci U S A. 2016 Jan 5; 113(1): E51–E60. Published online 2015 Dec 22. doi: 10.1073/pnas.1517041113
PMCID:
PMC4711844
AbstractArticlePDF–1.7M
13.
The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment
Wei Yang, Yun-Hwa Lee, Amanda E. Jones, Jessica L. Woolnough, Dewang Zhou, Qian Dai, Qiang Wu, Keith E. Giles, Tim M. Townes, Hengbin Wang
Nat Commun. Author manuscript; available in PMC 2014 Nov 2.
Published in final edited form as: Nat Commun. 2014; 5: 3818. Published online 2014 May 2. doi: 10.1038/ncomms4818
PMCID:
PMC4060806
AbstractArticlePDF–1.0M
14.
Novel Protein Interactions with Endoglin and Activin Receptor-like Kinase 1: Potential Role in Vascular Networks
Guoxiong Xu, Miriam Barrios-Rodiles, Mirjana Jerkic, Andrei L. Turinsky, Robert Nadon, Sonia Vera, Despina Voulgaraki, Jeffrey L. Wrana, Mourad Toporsian, Michelle Letarte
Mol Cell Proteomics. 2014 Feb; 13(2): 489–502. Published online 2013 Dec 7. doi: 10.1074/mcp.M113.033464
PMCID:
PMC3916649
AbstractArticlePDF–4.1M
15.
Usp16 contributes to somatic stem cell defects in Down syndrome
Maddalena Adorno, Shaheen Sikandar, Siddhartha S. Mitra, Angera Kuo, Benedetta Nicolis Di Robilant, Veronica Haro-Acosta, Youcef Ouadah, Marco Quarta, Jacqueline Rodriguez, Dalong Qian, Vadiyala M. Reddy, Samuel Cheshier, Craig C. Garner, Michael F. Clarke
Nature. Author manuscript; available in PMC 2014 Mar 19.
Published in final edited form as: Nature. 2013 Sep 19; 501(7467): 380–384. Published online 2013 Sep 11. doi: 10.1038/nature12530
PMCID:
PMC3816928
AbstractArticlePDF–1.1M
16.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
17.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
18.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K
19.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K
20.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K

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