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Select item 114236781.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 113624592.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 111057503.

Folding and assembly defects of pyruvate dehydrogenase deficiency-related variants in the E1α subunit of the pyruvate dehydrogenase complex

Srdja Drakulic, Jay Rai, Steen Vang Petersen, Monika M. Golas, Bjoern Sander

Cell Mol Life Sci. 2018 Aug; 75(16): 3009–3026. Published online 2018 Feb 14. doi: 10.1007/s00018-018-2775-2

PMCID:: PMC11105750

Abstract Article PDF–4.6M

Select item 110241854.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724775.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687276.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988587.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107700428.

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence

Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L. Höög, Martin Ott, Claes Andréasson, Sabrina Büttner

Nat Commun. 2024; 15: 315. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44538-8

PMCID:: PMC10770042

Abstract Article PDF–5.1M

Select item 107001389.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 1051470010.

Xrn1 biochemically associates with eisosome proteins after the post diauxic shift in yeast

Baptiste Courtin, Abdelkader Namane, Maite Gomard, Laura Meyer, Alain Jacquier, Micheline Fromont-Racine

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000926. Published online 2023 Sep 7. doi: 10.17912/micropub.biology.000926

PMCID:: PMC10514700

Abstract Article PDF–1.7M

Select item 1029770011.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 1023336812.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 1006833613.

MitoStores: chaperone‐controlled protein granules store mitochondrial precursors in the cytosol

Lena Krämer, Niko Dalheimer, Markus Räschle, Zuzana Storchová, Jan Pielage, Felix Boos, Johannes M Herrmann

EMBO J. 2023 Apr; 42(7): e112309. Published online 2023 Jan 27. doi: 10.15252/embj.2022112309

PMCID:: PMC10068336

Abstract Article PDF–3.9M

Select item 963802814.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 957451415.

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

Witold Jaworek, Marc Sylvester, Giovanna Cenini, Wolfgang Voos

J Biol Chem. 2022 Oct; 298(10): 102494. Published online 2022 Sep 15. doi: 10.1016/j.jbc.2022.102494

PMCID:: PMC9574514

Abstract Article PDF–1.9M

Select item 937443616.

Ubiquitination drives COPI priming and Golgi SNARE localization

Swapneeta S Date, Peng Xu, Nathaniel L Hepowit, Nicholas S Diab, Jordan Best, Boyang Xie, Jiale Du, Eric R Strieter, Lauren P Jackson, Jason A MacGurn, Todd R Graham

eLife. 2022; 11: e80911. Published online 2022 Jul 29. doi: 10.7554/eLife.80911

PMCID:: PMC9374436

Abstract Article PDF–4.3M

Select item 935556417.

A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins

Layla Drwesh, Benjamin Heim, Max Graf, Linda Kehr, Lea Hansen-Palmus, Mirita Franz-Wachtel, Boris Macek, Hubert Kalbacher, Johannes Buchner, Doron Rapaport

eLife. 2022; 11: e77706. Published online 2022 Jul 25. doi: 10.7554/eLife.77706

PMCID:: PMC9355564

Abstract Article PDF–8.6M

Select item 920981118.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224