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Items: 1 to 20 of 78

1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
2.
The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage
Chao Jin, Elias Einig, Wenshan Xu, Ravi Babu Kollampally, Andreas Schlosser, Michael Flentje, Nikita Popov
Nucleic Acids Res. 2024 Apr 12; 52(6): 3011–3030. Published online 2024 Jan 16. doi: 10.1093/nar/gkae004
PMCID:
PMC11024517
AbstractArticlePDF–2.8M
3.
USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells
Janardhan Keshav Karapurkar, Jencia Carminha Colaco, Bharathi Suresh, Apoorvi Tyagi, Sang Hyeon Woo, Won-Jun Jo, Nare Ko, Vijai Singh, Seok-Ho Hong, Seung Jun Oh, Kye-Seong Kim, Suresh Ramakrishna
Cell Mol Life Sci. 2024 Dec; 81(1): 145. Published online 2024 Mar 18. doi: 10.1007/s00018-024-05187-2
PMCID:
PMC10948558
AbstractArticlePDF–10M
4.
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells
Junjun Li, Jin Peng, Lingzhi Wu, Xiang Shen, Xinghua Zhen, Yimao Zhang, Huailu Ma, Yongfeng Xu, Qunli Xiong, Qing Zhu, Pumin Zhang
J Biol Chem. 2023 Jul; 299(7): 104856. Published online 2023 May 23. doi: 10.1016/j.jbc.2023.104856
PMCID:
PMC10404617
AbstractArticlePDF–2.9M
5.
Comprehensive prognostic and immunological analysis of Ubiquitin Specific Peptidase 28 in pan-cancers and identification of its role in hepatocellular carcinoma cell lines
Wuhan Zhou, Jiafei Chen, Jingui Wang
Aging (Albany NY) 2023 Jul 15; 15(13): 6545–6576. Published online 2023 Jul 13. doi: 10.18632/aging.204869
PMCID:
PMC10373984
AbstractArticlePDF–10M
6.
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer
Carina R. Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami, Lisa Schlicker, Felix C. E. Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A. Calzado, Martin Eilers, Nikita Popov, Mathias T. Rosenfeldt, Markus E. Diefenbacher, Almut Schulze
Cell Death Differ. 2023 Jul; 30(7): 1710–1725. Published online 2023 May 18. doi: 10.1038/s41418-023-01173-6
PMCID:
PMC10307777
AbstractArticlePDF–6.3M
7.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
8.
METTL5 stabilizes c‐Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression
Peng Xia, Hao Zhang, Haofeng Lu, Kequan Xu, Xiang Jiang, Yuke Jiang, Xiangdong Gongye, Zhang Chen, Jie Liu, Xi Chen, Weijie Ma, Zhonglin Zhang, Yufeng Yuan
Cancer Commun (Lond) 2023 Mar; 43(3): 338–364. Published online 2023 Jan 5. doi: 10.1002/cac2.12403
PMCID:
PMC10009668
AbstractArticlePDF–14M
9.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
10.
Ubiquitin‐specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma
Xiao Sun, Mengjiao Cai, Lingzhi Wu, Xinghua Zhen, Yuetong Chen, Jin Peng, Suxia Han, Pumin Zhang
Cancer Sci. 2022 Oct; 113(10): 3463–3475. Published online 2022 Aug 11. doi: 10.1111/cas.15509
PMCID:
PMC9530868
AbstractArticlePDF–26M
11.
Identification and validation of Selective Deubiquitinase Inhibitors
Anthony C. Varca, Dominick Casalena, Wai Cheung Chan, Bin Hu, Robert S. Magin, Rebekka M. Roberts, Xiaoxi Liu, He Zhu, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jarrod A. Marto, Douglas Auld, Sara J. Buhrlage
Cell Chem Biol. Author manuscript; available in PMC 2022 Dec 16.
Published in final edited form as: Cell Chem Biol. 2021 Dec 16; 28(12): 1758–1771.e13. Published online 2021 Jun 14. doi: 10.1016/j.chembiol.2021.05.012
PMCID:
PMC9473745
AbstractArticlePDF–2.3M
12.
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K
Cristian Prieto‐Garcia, Oliver Hartmann, Michaela Reissland, Fabian Braun, Süleyman Bozkurt, Nikolett Pahor, Carmina Fuss, Andreas Schirbel, Christina Schülein‐Völk, Alexander Buchberger, Marco A. Calzado Canale, Mathias Rosenfeldt, Ivan Dikic, Christian Münch, Markus E. Diefenbacher
Mol Oncol. 2022 Sep; 16(17): 3082–3106. Published online 2022 Apr 30. doi: 10.1002/1878-0261.13217
PMCID:
PMC9441007
AbstractArticlePDF–13M
13.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
14.
USP37 Deubiquitinates CDC73 in HPT-JT Syndrome
Su Yeon Kim, Ji-young Lee, Yun-jung Cho, Kwan Hoon Jo, Eun Sook Kim, Je Ho Han, Kwang-Hyun Baek, Sung-dae Moon
Int J Mol Sci. 2022 Jun; 23(12): 6364. Published online 2022 Jun 7. doi: 10.3390/ijms23126364
PMCID:
PMC9224168
AbstractArticlePDF–4.8M
15.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
16.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
17.
Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
Rachel K. Toth, Regina Solomon, Noel A. Warfel
Cells. 2022 Mar; 11(6): 1006. Published online 2022 Mar 16. doi: 10.3390/cells11061006
PMCID:
PMC8947361
AbstractArticlePDF–2.4M
18.
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling
Sara Vanessa Bernhard, Katarzyna Seget-Trzensiok, Christian Kuffer, Dragomir B. Krastev, Lisa-Marie Stautmeister, Mirko Theis, Kristina Keuper, Jan-Eric Boekenkamp, Maik Kschischo, Frank Buchholz, Zuzana Storchova
Cell Oncol (Dordr) 2022; 45(1): 103–119. Published online 2021 Dec 28. doi: 10.1007/s13402-021-00654-5
PMCID:
PMC8881269
AbstractArticlePDF–3.4M
19.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
20.
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells
Jiewei Wang, Yiping Dong, Huailu Ma, Lingzhi Wu, Xinghua Zhen, Lichun Tang, Jianping Jin, Suxia Han, Pumin Zhang, Jin Peng
J Biol Chem. 2022 Jan; 298(1): 101443. Published online 2021 Nov 22. doi: 10.1016/j.jbc.2021.101443
PMCID:
PMC8733264
AbstractArticlePDF–2.8M

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